3 results match your criteria: "University of Califo[Affiliation]"

Significance: Mid-infrared (IR) imaging based on the vibrational transition of biomolecules provides good chemical-specific contrast in label-free imaging of biology tissues, making it a popular tool in both biomedical studies and clinical applications. However, the current technology typically requires thin and dried or extremely flat samples, whose complicated processing limits this technology's broader translation.

Aim: To address this issue, we report mid-IR photoacoustic microscopy (PAM), which can readily work with fresh and thick tissue samples, even when they have rough surfaces.

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Real-Time Monitoring of Suprachoroidal Space (SCS) Following SCS Injection Using Ultra-High Resolution Optical Coherence Tomography in Guinea Pig Eyes.

Invest Ophthalmol Vis Sci

June 2015

Institute of Ocular Pharmacology, School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China 2Jacob's Retina Center at Shiley Eye Institute, Department of Ophthalmology, University of California San Diego, La Jolla, Califo.

Purpose: To monitor the change of suprachoroidal space (SCS) using ultra high resolution-optical coherence tomography (UHR-OCT) following SCS injection with different drug formulations.

Methods: An amount of 10 or 20 μL of saline or indocyanine green (ICG) or triamcinolone acetonide (TA) suspension (40 or 80 mg/mL) was injected suprachoroidally into the guinea pig eye with a 30-gauge needle. Immediately after injection, the eyes were imaged by UHR-OCT from 60 minutes up to 24 hours.

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