A systematic review of health promoting effects of consumption of whey-based fermented products on adults.

Introduction: Fermented whey-based products show significant potential as functional foods, owing to their rich nutritional profile and the generation of bioactive compounds during fermentation. This systematic narrative review evaluates the health effects of fermented-whey consumption based on evidence from human studies in adults.

Methods: A systematic literature search was conducted using electronic databases including, PubMed, Scopus, and Cochrane Library for studies published between 1.

Dimethyl Isosorbide: An Innovative Bio-Renewable Solvent for Sustainable Chromatographic Applications.

The increasing environmental concerns and regulatory restrictions on toxic conventional solvents have driven the search for sustainable alternatives. Dimethyl isosorbide (DMI), a bio-renewable solvent, has shown potential as a replacement for short-chain glycol ethers, although its use as solvent in liquid chromatography (LC) is underexplored. This study presents a physicochemical characterization of DMI with a particular focus on its application as an innovative solvent in LC analyses.

Nickel cobalt selenide as a nano-moss electrocatalyst for detection of gaseous hydrogen peroxide.

Nanoparticles composed specifically of transition metals have demonstrated significant potential not only in electrocatalysis but also in electroanalysis. In this context, this work presents a comprehensive investigation into the electrocatalytic properties of NiCoSe nanomaterials, specifically designed for hydrogen peroxide (HO) detection. The unique needle-like nano-moss morphology of NiCoSe, confirmed through scanning electron microscopy (SEM), scanning and transmission electron microscopy (STEM), and high-angle annular dark-field (HAADF) analysis, reveals a highly organized structure with a large surface area, critical for enhanced catalytic performance.

Bias in vital signs? Machine learning models can learn patients' race or ethnicity from the values of vital signs alone.

Objectives: To investigate whether machine learning (ML) algorithms can learn racial or ethnic information from the vital signs alone.

Methods: A retrospective cohort study of critically ill patients between 2014 and 2015 from the multicentre eICU-CRD critical care database involving 335 intensive care units in 208 US hospitals, containing 200 859 admissions. We extracted 10 763 critical care admissions of patients aged 18 and over, alive during the first 24 hours after admission, with recorded race or ethnicity as well as at least two measurements of heart rate, oxygen saturation, respiratory rate and blood pressure.

Prevalence of Hidradenitis Suppurativa in Skopje, North Macedonia.

Introduction: Hidradenitis suppurativa (HS) exhibits varying prevalence globally, markedly influenced by geographical and ethnic distinctions. This study, part of the Global Hidradenitis Suppurativa Atlas (GHiSA) initiative, aimed to assess the prevalence of HS in North Macedonia and contribute to the global epidemiology of this complex dermatological disorder.

Methods: Conducted at City General Hospital "8th September" in Skopje, North Macedonia, from March 23, 2023, to May 30, 2023, this single-center study enrolled 597 healthy adults using a validated screening questionnaire.

Air pollution data: A dataset gathered through a crowd sensing platform.

This paper introduces an extensive dataset on air pollution monitoring, collected through a crowd sensing IoT platform. The dataset contains real-time measurements of various pollutants, including PM, PM, NO, O, and CO, enriched with meteorological parameters such as temperature, humidity, and atmospheric pressure. Additionally, it includes noise level measurements, offering insights into urban noise pollution.

Synthesis, Biological Evaluation, and Molecular Docking Studies of Novel Coumarin-Triazole-Isatin Hybrids as Selective Butyrylcholinesterase Inhibitors.

A series of 21 novel coumarin-triazole-isatin hybrids was synthesized and evaluated for their potential as multitarget agents in Alzheimer's disease (AD). The compounds featured variations in alkyl linker length that connects coumarin and triazole and substitution at the 5-position of the isatin ring. Several derivatives showed potent butyrylcholinesterase (BChE) inhibition with selectivity over acetylcholinesterase (AChE).

Assessing the Distribution of Potentially Toxic Elements in Bryophytes in Relation to Surface Soil Contamination in the Veles Region, North Macedonia.

This study explores the relationship between bryophyte (mosses) diversity and environmental factors in the Veles region, North Macedonia, focusing on the spatial distribution of chemical elements in the moss and surface soil samples collected from the same locations. Eighteen moss samples were analyzed alongside surface soils. Advanced spectrometric techniques were used to identify potentially toxic elements (PTEs) and their links to anthropogenic and natural sources.

Methods to assess on-farm biosecurity in Europe and beyond.

The aim of this study was to identify which biosecurity assessment methods (BAMs) are currently used in practice in animal farms. To address this, a structured questionnaire was developed to gather information such as the animal species, main objectives, type of enforcement, output generated and feedback of the result. In the context of the BETTER Cost Action project, country representatives identified in each of their countries which BAMs were used and completed an online survey.

Models of care and associated targeted implementation strategies for cancer survivorship support in Europe: a scoping review protocol.

Introduction: Cancer and its treatments can lead to a wide range of side-effects that can persist long after treatments have ended. Across Europe, survivorship care is traditionally hospital-based specialist-led follow-up, leading to gaps in supportive care. Improved screening, diagnosis and treatment increase survival rates.

Spatial distribution and isotopic signatures of N and C in mosses across Europe.

The accumulation of nitrogen (N) in moss tissue has proven to be a reliable marker of increasing N deposition. However, this measurement does not offer additional data about the origin of pollution. In this respect, the analysis of the N isotopic ratios might be a helpful tool in providing supplementary information about the nature of the nitrogenous species in biomonitoring surveys.

Anatomy education and clinical practice: students' views.

Background And Objectives: This study aimed to evaluate students' perspectives on the relevance of anatomy education to clinical practice throughout their studies at the Faculty of Medicine in Skopje.

Materials And Methods: The study was designed as a cross-sectional, questionnaire-based investigation and took place at the Faculty of Medicine in Skopje at the University of "Ss Cyril and Methodius", R. North Macedonia.

Living with COPD and its psychological effects on participating in community-based physical activity in Brazil: a qualitative study. Findings from the Breathe Well group.

Physical activity (PA) improves dyspnoea, psychological wellbeing and quality of life (QoL) for people with COPD reducing their risk of exacerbation. However, engagement in PA is low especially amongst those with anxiety and depression, and PA programmes are limited in countries with limited resources such as Brazil. We explored perceptions of 21 people with COPD about the impact of their disease on taking part in community-based PA programmes in Sao Paulo, Brazil through semi-structured telephone interviews from October 2020 to April 2021.

Towards harmonized laboratory methodologies in veterinary clinical bacteriology: outcomes of a European survey.

Introduction: Veterinary clinical microbiology laboratories play a key role in antimicrobial stewardship, surveillance of antimicrobial resistance and prevention of healthcare associated-infections. However, there is a shortage of international harmonized guidelines covering all steps of veterinary bacterial culture from sample receipt to reporting.

Methods: In order to gain insights, the European Network for Optimization of Veterinary Antimicrobial Treatment (ENOVAT) designed an online survey focused on the practices and interpretive criteria used for bacterial culture and identification (C&ID), and antimicrobial susceptibility testing (AST) of animal bacterial pathogens.

Access to diagnostic imaging and radiotherapy technologies for patients with cancer in the Baltic countries, eastern Europe, central Asia, and the Caucasus: a comprehensive analysis.

Background: Only 10-40% of patients with cancer in low-income and middle-income countries were able to access curative or palliative radiotherapy in 2015. We aimed to assess the current status of diagnostic imaging and radiotherapy services in the Baltic countries, eastern Europe, central Asia, and the Caucasus by collecting and analysing local data.

Methods: This Access to Radiotherapy (ART) comprehensive analysis used data from 12 countries: the three Baltic countries (Estonia, Latvia, and Lithuania), two countries in eastern Europe (Moldova and Ukraine), four countries in central Asia (Kazakhstan, Kyrgyzstan, Tajikistan, and Uzbekistan), and three countries in the Caucasus (Armenia, Azerbaijan, and Georgia), referred to here as the ART countries.

Strengthening Clinician-Researchers' Communication and Knowledge Translation Skills: An Innovative Game Model From the Breathe Well Group.

Communication is a core component of a clinician's role; however, when clinicians conduct research, communicating the emerging findings and recommendations to different types of stakeholders can be unfamiliar territory. Communicating research to advocate for change can be even more challenging. Clinician researchers seeking to be agents for change need to conceive and craft specific, evidence-based messages and communicate these effectively to different stakeholders to negotiate action.

Genuine anodic and cathodic current components in cyclic voltammetry.

Implicit anodic and cathodic current components associated with the real net current at a given potential of a simple quasireversible electrode reaction can be accurately estimated using basic mathematical modeling within the framework of Butler-Volmer electrode kinetics. This methodology requires only prior knowledge of the formal potential of the dissolved redox couple, offering direct insight into the electrode kinetics. The proposed approach facilitates a unique transformation of a conventional cyclic voltammogram, allowing the replacement of the common, net current with authentic anodic and cathodic current components.

Genuine differential voltammetry.

A novel form of differential voltammetry is proposed, developed through the implicit anodic and cathodic current components of the experimentally accessible conventional net current measured in a voltammetric experiment. By employing basic mathematical modelling of an electrode reaction of a dissolved redox couple at a conventional, macroscopic electrode within the framework of the Butler-Volmer electrode kinetic model, the implicit anodic and cathodic current components of the net conventional current are clearly defined and can be estimated. Consequently, a novel form of differential current, calculated as the difference between anodic and cathodic implicit current components associated with a single potential of the voltammetric experiment, can be established.

Assessment of radiological hazards of soils from the city of Bitola (Macedonia) and its environs.

To establish the radioactivity level of soils and assess the associated radiological impact on residents, 58 samples from the town of Bitola and its environs were collected. After conducting gross alpha and gross beta measurements with a gas-flow proportional counter as a preliminary screening test, subsequent gamma-spectrometry measurements reveal the presence of K, Ra, Th, and Cs in the soil samples as radionuclides with the highest impact. The absorbed gamma dose rate, the annual effective dose, radium equivalent activity, external hazard index, gamma index, excess lifetime cancer risk, and annual gonadal dose were calculated using the obtained activity concentrations of the radionuclides.

High economic inequality is linked to greater moralization.

Throughout the 21st century, economic inequality is predicted to increase as we face new challenges, from changes in the technological landscape to the growing climate crisis. It is crucial we understand how these changes in inequality may affect how people think and behave. We propose that economic inequality threatens the social fabric of society, in turn increasing moralization-that is, the greater tendency to employ or emphasize morality in everyday life-as an attempt to restore order and control.

Distribution of some natural and artificial radionuclides in soil from the city of Bitola (Macedonia) and its environs.

The aim of the study is a thorough investigation of the radioactivity level in soils of the town of Bitola (Macedonia) and its environs. Topsoil samples collected from 58 locations within a 5 × 5 km grid were analysed. Serving as a screening, gross alpha and beta activity measurements were performed using gas-flow proportional counter.

Rapid quantification models for assessing melamine adulteration in sport nutrition supplements via benchtop and portable NIRS instruments.

Sport nutrition supplements (SNS) are vulnerable to adulteration with melamine, artificially augmenting their protein content as determined by conventional assay methodologies. Vibrational spectroscopy techniques are suitable for the detection of adulteration because they allow rapid analysis, require minimal sample preparation, and can perform numerous analyses in a short time. The aim of this study was to develop rapid quantification models for the determination of melamine adulteration in a variety of SNS matrices using NIRS (near-infrared spectroscopy) in combination with multivariate data processing.