Papillary Tumors of the Pineal Region (PTPR) in Pediatric Population: A Case Report and Literature Review.

Papillary tumors of the pineal region (PTPR) are rare central nervous system neoplasms, with a limited number of pediatric cases reported in the literature. Their optimal management remains unclear due to their unpredictable biological behavior and high recurrence rates. This study presents the clinical course, treatment, and long-term follow-up of a 3-year-old child diagnosed with PTPR.

An Effect of Smelled Breast Milk During and After Venous Blood Drawing on Newborn Infants' Pain and Comfort Level.

This study was conducted as a randomized controlled trial to evaluate the effect of breast milk odor on pain and stress levels during venous blood sampling. Data were collected from 60 newborn infants consisting of a total of 30 infants in the experimental group and 30 in the control group who were hospitalized in the Intensive Care Unit between 7 December 2022 and 25 September 2023. The data were collected using the Newborn Infant Pain Scale and Premature Infant Comfort Scale forms.

Development, Validity and Reliability of the Avoidance of Sports Activities Photo Scale (ASAP-Shoulder-Scale) in Athletes With Shoulder Pain.

Background: Fear-avoidance beliefs and kinesiophobia can contribute to shoulder pain-related avoidance behavior. In athletes, symptoms may only become apparent during training and competition. To identify shoulder pain-related avoidance behaviors, a standardized screening tool is needed.

Evaluation of serum ischemia-modified albumin levels in high-normal blood pressure category.

Background: High-normal blood pressure (BP), situated inside the elevated normal range and indicative of potential hypertension, is widely acknowledged as a critical worldwide health issue. High-normal BP levels consist of a systolic measurement of 130-139 mmHg and a diastolic measurement of 85-89 mmHg. Ischemia-modified albumin (IMA) is a sign that tissues are not getting enough oxygen, which is also known as tissue hypoxia.

Evaluating Secukinumab as Treatment for Axial Spondyloarthritis and Psoriatic Arthritis in Patients with Comorbidities: Multicenter Real-Life Experience.

: Secukinumab is a fully human monoclonal antibody that targets interleukin (IL)-17A and is used to treat axial spondyloarthritis (axSpA) and psoriatic arthritis (PsA). Treating axSpA and PsA can be challenging in patients with comorbidities. In this multicenter retrospective study, we aimed to evaluate the efficacy and safety of secukinumab treatment in patients with axSpA and PsA who had a history of tuberculosis, multiple sclerosis (MS), or congestive heart failure (CHF).

Clinical and biological determinants of short and long term responses to somatostatin analogue therapy in acromegaly patients.

Purpose: This study investigated the impact of preoperative clinical/biochemical factors and postoperative adenoma granulation patterns on short and long term responses to somatostatin analogue (SSA) therapy in acromegaly patients.

Methods: Sixty patients who did not achieve remission after initial surgery were included. Thirty achieved biochemical control at 1 year, while 30 did not respond to first-line SSA therapy.

Cognitive dysfunction and depression in chemotherapy patients: a cross-sectional study from Turkey.

Objective: This study investigates the relationship between cognitive function and depression in cancer patients receiving chemotherapy.

Methods: A cross-sectional study design was employed, involving 80 cancer patients undergoing chemotherapy. Data were collected using the Socio-Demographic Information Form, the Functional Assessment of Cancer Therapy-Cognitive Function (FACT-Cog), and the Beck Depression Inventory (BDI).

Evaluation of fatigue levels of individuals with chronic diseases: from the perspective of student nurses and patients.

Background: The evaluation of fatigue experienced by individuals with chronic diseases by nursing students and patients is very important in terms of improving the quality of care.

Method: The study was conducted in a descriptive cross-sectional manner between November and December 2022 with students in the nursing department of the Faculty of Health Sciences of a state university located in a province, and patients receiving treatment in the clinic with a diagnosis of chronic disease to which these students cared during their clinical practice. The study population consisted of all nursing students at the specified faculty and individuals diagnosed with chronic diseases hospitalized in relevant clinics, and the sample consisted of 221 students and 442 patients, in line with the power analysis.

Self-Management and Affecting Factors in Dialysis Patients Experiencing the Earthquake in Türkiye.

Objectives: The present study was conducted to determine self-management and influencing factors in dialysis patients who experienced the earthquake.

Methods: The study was conducted descriptively with 125 patients receiving dialysis in a city affected by the earthquake in Türkiye. Data were collected with the "Personal Information Form" and the "Chronic Illness Self-Management Scale" (CISMS).

The joint ınvolvement pattern of granulomatous polangiitis changed? Multicenter study.

Objectives: Granulomatosis with polyangiitis (GPA) formerly Wegener's granulomatosis is a type of anti-neutrophil cytoplasm antibody (ANCA)-associated vasculitis (AAV) typically associated with necrotizing, granulomatous inflammation. Musculoskeletal manifestations have been described in 40-65% of patients. Arthritis usually occurs as large, single and asymmetric joint involvement, but rarely symmetrical small joint involvement may also occur.

Characterization of the mechanical changes of adductor muscles in the lower extremities for patients with multiple sclerosis.

Background: It is important to know how the mechanical properties of the muscles change in the management of adductor spasticity in patients with Multiple Sclerosis (pwMS).

Methods: This study was conducted by evaluating forty-two pwMS bilaterally. The Modified Ashworth Scale (MAS) was used to determine the hip adductor spasticity level, and pwMS were divided into four groups (MAS0, MAS1, MAS1+, MAS2) regarding the MAS grade.

Causes of diagnostic and treatment delays in locally advanced breast cancer: a nationwide multicenter survey and electronic health records analysis in Turkiye.

Delays in breast cancer (BC) diagnosis and treatment negatively impact survival outcomes. Understanding patient- and provider-related factors behind these delays is crucial. This study aimed to identify nationwide reasons for delayed diagnosis and treatment of locally advanced BC in Turkiye.

The Joint Role of Serum Markers of Congestion or Myocardial Necrosis And Speckle Tracking Echocardiography in The Detection of Early Subtle Chemotherapy-Induced Cardiotoxicity in Women With Breast Cancer.

Aim     To monitor the dynamics of biomarkers during chemotherapy, targeted chemotherapy and targeted monotherapy in patients with HER2-positive breast cancer (BC); to analyze the emergence timing of these changes; to compare early biochemical and echocardiographic criteria; and to determine the best time for assessing latent subclinical cardiac dysfunction.Material and methods            Patients with BC (229 women aged 57±11 years) treated sequentially with anthracyclines, a combination of docetaxel and trastuzumab, and trastuzumab monotherapy were examined during three blocks of BC therapy until the development of clinical cardiotoxicity. Time-related changes in high-sensitivity cardiac troponin I, N-terminal pro-brain natriuretic peptide (NT-proBNP), left ventricular (LV) global longitudinal strain (GLS) and LV ejection fraction (EF) (up to 12 speckle-tracking echocardiograms/up to 12 laboratory tests) were analyzed.

Safety and Efficacy of Cladribine in Patients Discontinuing Fingolimod Due to Elevated Transaminase Levels: The FinClad Study.

Background: Elevated liver enzymes pose a significant challenge for patients with multiple sclerosis (pwMS) undergoing treatment with fingolimod. Cladribine has demonstrated comparable efficacy with a more favorable safety profile in terms of hepatotoxicity risk. However, there is still limited data regarding the transition from fingolimod to cladribine for patients with elevated transaminase levels.

Assessment of testicular parenchyma in COVID-19 patients: a case-control study using ultrasound histogram analysis.

Objective: Uncontrolled activation of immune cells, such as lymphocytes and macrophages, can result in heightened inflammatory cytokine production, leading to oxidative stress and cell death in various organs, including the brain and testes. The systemic effects of COVID-19 are not limited to the respiratory system and can also affect other organs. The aim of this study was to focus on the possible effects of COVID-19 infection on the testicles in male patients.

THE RELATIONSHIP BETWEEN POTENTIAL DIET INFLAMMATORY LOAD AND CHEMERIN, ANDROGENS AND INSULIN RESISTANCE IN WOMEN WITH POLYCYSTIC OVARY SYNDROME.

Background: In recent years, the effect of inflammation on the pathophysiology of polycystic ovary syndrome (PCOS) has attracted considerable attention. However, the effect of the dietary inflammatory load remains unclear.

Objective: This study was conducted to evaluate the relationship between dietary inflammatory index (DII) score and serum chemerin concentration, biochemical hyperandrogenism and insulin resistance in women with PCOS.

Association of fibrinogen-to-albumin ratio in patients with isolated coronary artery ectasia.

Background: Previous research has indicated that chronic inflammation plays a significant role in the development of coronary artery ectasia (CAE). However, there is limited data on the role of plasma fibrinogen-to-albumin ratio (PFAR) in CAE patients. Our study aimed to explore the connection between PFAR and the presence of CAE.

Post-earthquake psychiatric manifestations in Gaziantep - Turkey: An evaluation of clinical features within the first month following the Kahramanmaraş twin earthquakes.

Background: This study aimed to investigate the prevalence of psychiatric disorders among earthquake survivors who sought psychiatric consultation at outpatient clinics in the aftermath of the Kahramanmaras Twin Earthquakes (Mw 7.8 and Mw 7.5).

A preliminary study using luminol-enhanced intraoperative bile duct imaging technique in rabbits.

In the literature, a variety of techniques are recommended for intraoperative biliary tract imaging. The objective of this study was to develop a more cost-effective and widely applicable technique that could serve as an alternative to existing imaging techniques by taking advantage of the chemiluminescence effect of luminol. An experimental study using rabbits was designed.

A Computed Tomography-Based Morphometric Assessment of the Foramen Lacerum in a Turkish Population Using the 3D Slicer Method.

: The foramen lacerum (FL), located at the base of the skull, is generally considered the safest anatomical pathway for accessing the internal carotid artery (ICA) and the vidian canal (VC) during surgical procedures. We aimed to evaluate the morphometric characteristics of FL, VC, and related structures. This study utilized cranial computed tomography (CT) images obtained between 2016 and 2018 at Balıkesir University Faculty of Medicine for various clinical indications.

A Comparison of Two Different Scales in Identifying the Risk of Falls in Leukaemia and Lymphoma Patients.

Aim: This study was conducted to assess the risk of falls in leukaemia and lymphoma patients using the Itaki Fall Risk Scale and the Fall Risk Assessment Scale Developed by the Delmarva Foundation and compare the data collected.

Design: This study is descriptive and cross-sectional.

Methods: The sample consisted of 84 patients diagnosed with leukaemia and lymphoma who were hospitalised in the haematology ward between March 2021 and December 2021.

Basilar Invagination Diagnosis, Classification, and Radiology: WFNS Spine Committee Recommendations.

Study Design: A systematic literature review and consensus using Delphi method.

Objective: This review aimed to analyze recent literature on diagnosis, classification, and radiologic characteristics of Basilar Invagination (BI) to generate recommendations on these topics.

Summary Of Background: Basilar invagination diagnosis, classifications, and radiologic characteristics evolved during the last decade; however, many debatable criteria disturb a common language fundamental to compare clinical research.

Dermatological Comorbidities Accompanying Rosacea and Their Relationship with Clinical and Demographic Features, Quality of Life, and Systemic Comorbidities: A Retrospective, Case-Controlled, Multicenter Survey.

Introduction: As rosacea patients are generally light-skinned and photosensitized some sun-related skin findings are likely to be observed. This study aimed to determine which dermatological comorbidities accompany rosacea and evaluate their relationship with clinical, demographic, quality-of-life, and systemic comorbidities.

Methods: This case-control multicenter study was conducted by the Turkish Society of Dermatology Acne Study Group.

Idiopathic granulomatous mastitis: TNFi effectivity in a retrospective inception cohort.

Objectives: Idiopathic granulomatous mastitis is a rare, chronic, inflammatory breast disease that can mimic breast carcinoma. Histologicaly there are giant cells and epitheloid histiocytes forming non-caseating granulomas. Corticosteroids, methotrexate, azathioprine, intralesional corticosteroid injection can be used as the first step drugs in the treatment of patients with Idiopathic granulomatous mastitis, but the next step is unclear in a group of patients who are resistant to these treatments.

HLA B subtype analysis in patients developing tuberculosis during anti-TNF treatment.

In this study, we aimed to evaluate HLA-B subtypes in cases developing TB while using anti-TNF agents and to compare with the HLA-B subtypes of three different groups including community-acquired TB cases, anti-TNF patients without TB and healthy controls. The study consisted of four groups. Group 1: 35 community-acquired TB patients, group 2; 47 anti-TNF-TB patients, group 3; 61 anti-TNF (non TB) patients and group 4; 40 healthy controls.