Assessing Heavy Metals using ICP-MS in Fruits from the Developing World and their Associated Health Risks.

This study investigates heavy metal contamination across ten fruit varieties cultivated in Rampal and assesses the potential health risks associated with their consumption. Eight metals-Fe, Cu, Cd, Zn, Cr, Mn, Pb, and As were analyzed using an inductively coupled plasma mass spectrometer. Health risk indicators, including estimated daily intake (EDI), target hazard quotient (THQ), hazard index (HI), and cumulative carcinogenic risk (CR), were employed.

Toll-like Receptor (TLR) Response in Chikungunya Virus Infection: Mechanism of Activation, Immune Evasion, and Use of TLR Agonists in Vaccine Development.

CHIKV is a re-emerging mosquito-borne arthritogenic alphavirus associated with large outbreaks and severe joint pain, and it poses a growing global health threat. Toll-like receptors (TLRs), as key pattern recognition receptors, detect viral components and initiate antiviral immune responses. Increasing evidence highlights the role of TLR signaling in shaping CHIKV infection outcomes, though its precise contribution remains unclear.

Early pregnancy detection in ruminants: challenges and innovations.

Precise and early pregnancy detection is crucial for better breeding management and enhancing the overall production of ruminant livestock. Throughout the years, numerous methods have evolved for pregnancy detection in ruminants, each possessing specific advantages and limitations. This review thoroughly discusses both traditional and emergent diagnostic methods, emphasizing their principles, implementation, merits and challenges.

Research experience and career factors in relation to mental health problems: Prevalence, risk factors, and machine learning-based predictive estimates.

Background: Mental health issues, including depression, anxiety, and insomnia, are increasingly prevalent among university students and graduates, especially those involved in academic research. The impact of research-related characteristics on mental health remains underexplored.

Aim: We examined this relationship using machine learning alongside traditional statistical analyses and GIS mapping.

Genogroup-Specific Multiplex Reverse Transcriptase Loop-Mediated Isothermal Amplification Assay for Point-of-Care Detection of Norovirus.

Norovirus is a major cause of acute gastroenteritis worldwide. Considering its highly infectious and transmissible nature, rapid and accurate diagnostic tools are of utmost importance for the effective control of outbreaks in the context of point-of-care testing (POCT). In this study, we developed a genogroup-specific multiplex reverse transcriptase loop-mediated isothermal amplification assay to detect the human norovirus genogroups I and II (GI and GII, respectively).

Assessing chemical properties and heavy metals in groundwater resources in a developing country: a baseline study.

Less information is available on the physicochemical properties conferring groundwater quality in the ancient Capital of the Pundranagar region, Bangladesh. This study preliminarily evaluates the quality of groundwater beneath rivers, ponds, and rice fields in northern Bangladesh. Probable causes of heavy metals contamination in groundwater, health hazards, and spatial variations were evaluated.

Food Allergy Knowledge, Attitudes, and Practices Among Restaurant's Staff in Bangladesh: A Structural Modeling Approach.

Food-related allergic reactions are increasingly prevalent in restaurant settings, often leading to severe and life-threatening incidents. This study aimed to investigate the relationships among knowledge, attitudes, and management practices related to food allergies in restaurant staff in Bangladesh. A cross-sectional study conducted between January and May 2024 assessed food allergy knowledge, attitudes, and practices among 712 restaurant staff across eight divisional areas in Bangladesh, using structured face-to-face interviews.

Assessing heavy metals toxicity in marine bed sediments of the Bay of Bengal: A novel baseline study on geochemical speciation, source, and risks.

The crucial marine water body, i.e., the Bay of Bengal in Bangladesh, is threatened due to heavy metal contamination.

Innate Immune Response to Powassan Virus Infection: Progress Toward Infection Control.

Powassan virus is an emerging tick-borne flavivirus that poses a significant threat to human health. The outcome of Powassan virus infection is shaped by both viral factors and the host immune response. While this review aimed to examine the innate immune response, particularly toll-like receptor-mediated immune responses to Powassan virus, data specific to the immune response to Powassan virus remain scarce.

Microplastic toxicity in fish: A potential review on sources, impacts, and solution.

Microplastics are a growing environmental concern, particularly in aquatic ecosystems and seafood safety. This review article explores the sources of microplastics in fish, their effects on fish health and behaviour, the potential risks to human health, and possible solutions. The primary sources of microplastics include the breakdown of larger plastic debris, wastewater discharge, industrial activities, landfills, and agricultural practices.

Shoreline dynamics in response to sea-level changes on the eastern coast of Bangladesh.

The eastern coast of Bangladesh has undergone significant geomorphic changes since 1990, with the shoreline predominantly prograding towards the Bay of Bengal. Analysis indicates that the northeastern (Mirsarai- Banshkhali) coast experienced seaward progradation, with a maximum progradation of 3.87 km and an average rate of 0.

Trends and factors contributing to changes in childhood stunting in Bangladesh from 2012 to 2019: A multivariate decomposition modelling.

Although the prevalence of childhood stunting has reduced in Bangladesh over time, it is still considered a major public health issue. While research has determined the risk factors for childhood stunting in Bangladesh, the factors that lead to reductions in stunting have received very little attention. Hence, we examined the factors contributing to the changes in childhood stunting over time in Bangladesh using a decomposition approach.

Predictive Modeling of Comorbid Depression and Anxiety Symptoms Among Prospective University Students: A GIS-Based and Machine Learning Study.

Prospective university students are highly susceptible to mental health issues such as depression and anxiety. This study investigates the prevalence and risk factors associated with comorbid depression and anxiety suffering, integrating GIS and Machine Learning techniques to comprehensively understand their spatial distribution and predictive factors. Data from 1485 participants were collected via a cross-sectional survey, encompassing socio-demographic details, educational backgrounds, psychological factors, and geographic locations.

Circulating Cell-Free DNA of Bovine Leukemia Virus: A Promising Biomarker for Enzootic Bovine Leukosis.

Bovine leukemia virus (BLV) causes Enzootic bovine leukosis (EBL) in approximately 1%-5% of infected cattle after a long latent period. Few biomarkers effectively distinguish non-EBL from EBL cattle. Given the rapid turnover of tumor cells, we hypothesized that cell-free DNA (cfDNA) in plasma could serve as a more effective biomarker for EBL diagnosis.

Effects of dietary Mango Kernel Meal (MKM) inclusion on growth indices, haemato-biochemical profiles, and growth and immune-regulatory genes of Gibelion catla.

Mango kernel meal (MKM) is an affordable and widely available industrial byproduct, commonly used as an aquaculture feed supplement due to its immuno-physiological properties. This study represents a novel effort to evaluate the dietary effect of MKM on growth, feed utilization, haemato-biochemical attributes, and expression of growth and immune genes in Gibelion catla. G.

Mental Health Consequences of COVID-19 Vaccine Side Effects: Findings From a Cross-Sectional Analysis.

Background And Aims: The COVID-19 pandemic has intensified pre-existing mental health issues in Bangladesh, yet no study has specifically examined how factors related to COVID-19 vaccination influence mental health within this context. This study aimed to examine the relationship between mental health symptoms, including depression, anxiety, and stress, and COVID-19 vaccination status and related factors among the adult Bangladeshi population.

Methods: A cross-sectional study with a convenience sampling technique was employed to gather the data.

Chemical Characterization, Antidiabetic and Antioxidant Potential of Peels Silver Nanoparticles Against Alloxan Induced Diabetes in Rabbits.

Diabetes is one of the major causes of death worldwide. Onion peels have antioxidant and antidiabetic activities due to the presence of flavonoids and phenolic compounds. In current research, the antidiabetic potential of a herbal-based silver nanodrug synthesized using aqueous extract of peels was studied against Alloxan-induced diabetes in rabbits.

Elevated oncogene expressions in koala infected with multiple koala retrovirus subtypes: a preliminary study.

Koala retrovirus (KoRV) causes multiple disease phenotypes in koalas, including carcinogenesis. The study aimed to assess oncogene expression in spleen tissues from ten deceased koalas coinfected with different subtypes and peripheral blood mononuclear cells (PBMCs) from two subclinically coinfected koalas with KoRV-A and KoRV-B. Initially, KoRV subtyping involved amplifying endogenous KoRV-A, and exogenous KoRV-B, -C specific env gene fragments, followed by sequencing.

Improving Guava Shelf Life and Preserving Postharvest Quality With Edible Coatings.

Guava ( L.) is a nutrient-dense climacteric fruit, but is prone to rapid postharvest deterioration due to physicochemical changes, leading to substantial quality and economic losses. This study investigated the efficacy of edible coatings-chitosan 2% (CH 2%), cinnamon essential oil 2% (CEO 2%), gel 30% (AVG 30%), propolis 10% (PR 10%), and gum arabic 10% (GA 10%)-applied individually and in combination (15 total formulations, excluding control) to extend shelf life and maintain postharvest quality.

Food safety practice and its associated factors among household food handlers in Patuakhali, Bangladesh: A cross-sectional study.

Food safety practices play a crucial role in the prevention of foodborne diseases, particularly in low- and middle-income countries like Bangladesh. This study assessed food safety practices among household food handlers in Patuakhali, Bangladesh, and identified associated factors influencing these practices. A cross-sectional study was conducted among 300 randomly selected households, using structured interviews and direct observations.

Association of sociodemographic factors and television food advertisements with junk food consumption among a sample of adolescents aged 13 to 17 in Magura district, Bangladesh: a cross-sectional survey.

Objectives: The aim of this study was to examine the association of sociodemographic factors and television advertisements with junk food consumption among adolescents aged 13 to 17 in Bangladesh.

Methods: This cross-sectional study included 326 adolescent-parent pairs from secondary education establishments at Magura municipal areas of Bangladesh. A validated structured survey questionnaire was utilized.

Seafood safety and consumption in coastal Bangladesh: unpacking knowledge, attitudes, preferences, and environmental concerns.

The objective of this study was to explore the knowledge and attitudes regarding seafood safety and consumption, along with preferences and environmental issues in coastal Bangladesh. A cross-sectional, consumer-based survey was conducted in Bangladesh from September to November 2023, targeting 1100 participants aged 18 years and older across seven coastal districts. Convenience sampling and in-person interviews were used for the data collection.

In vitro and in vivo anticancer activity of nickel (II) tetraazamacrocyclic diperchlorate complex, [(Ni-Me[14]diene)(ClO)] against ehrlich ascites carcinoma (EAC) and MCF7 cells.

Cancer remains a global health burden, with a pressing need for more effective treatments. This study uses a novel compound, Nickel (II) diperchlorate complex of the ligand (L): 3,10-C-meso-3,5,7,7,10,12,14,14-octamethyl-1,4,8,11-tetraazacyclotetradeca-4,11-diene, Me[14]diene, designated as [Ni(II)L](ClO), to explore its potential as an anticancer agent. Its efficacy was evaluated against Ehrlich Ascites Carcinoma (EAC)-bearing Swiss albino mice by monitoring tumor cell growth inhibition, survival time, tumor mass reduction, and hematological profiles.