5 results match your criteria: "National Quality Control Center of Digestive Endoscopy[Affiliation]"
Stool-based methylated syndecan-2 testing has a high positive predictive value in an average/increased-risk population: a multicenter retrospective study.
Gastroenterol Rep (Oxf)
August 2025
National Clinical Research Center for Digestive Diseases, National Quality Control Center of Digestive Endoscopy, Shanghai, P. R. China.
Introduction: Stool DNA testing based on methylated syndecan-2 (mSDC2) is a potential novel non-invasive screening test for colorectal cancer (CRC). This study aimed to assess its positive predictive value (PPV) in real-world practice.
Methods: This study retrospectively recruited consecutive patients with positive stool DNA-based SDC2 methylation tests from 18 hospitals between November 2016 and July 2021.
FIT-based risk-stratification model effectively screens colorectal neoplasia and early-onset colorectal cancer in Chinese population: a nationwide multicenter prospective study.
J Hematol Oncol
November 2022
Department of Gastroenterology/Digestive Endoscopy Center, Changhai Hospital, Second Military Medical University/Naval Medical University, National Clinical Research Center for Digestive Diseases (Shanghai), National Quality Control Center of Digestive Endoscopy, Shanghai, 200433, China. changhaibai
Article Synopsis
- A study was conducted in China to create a validated model for assessing the risk of colorectal neoplasia (CN) using a fecal immunochemical test (FIT) due to limited colonoscopy resources.
- The National Colorectal Polyp Care (NCPC) score was developed from eight factors and categorized individuals into low, intermediate, and high-risk levels for CN, guiding recommendations for colonoscopy.
- The model successfully identified a significant proportion of CN and early-onset colorectal cancers, demonstrating its effectiveness in a diverse population, including young individuals and those with nonspecific gastrointestinal symptoms.
Reduced Adenoma Miss Rate With 9-Minute vs 6-Minute Withdrawal Times for Screening Colonoscopy: A Multicenter Randomized Tandem Trial.
Am J Gastroenterol
May 2023
Department of Gastroenterology/Digestive Endoscopy Center, Changhai Hospital, Second Military Medical University/Naval Medical University; National Clinical Research Center for Digestive Diseases; National Quality Control Center of Digestive Endoscopy, Shanghai, China.
Introduction: Although the 9-minute mean withdrawal time (m-WT) is often reported to be associated with the optimal adenoma detection rate (ADR), no randomized trials of screening colonoscopy have confirmed the impact of a 9-minute m-WT on adenoma miss rate (AMR) and ADR.
Methods: A multicenter tandem trial was conducted in 11 centers. Seven hundred thirty-three asymptomatic participants were randomized to receive segmental tandem screening colonoscopy with a 9-minute withdrawal, followed by a 6-minute withdrawal (9-minute-first group, 9MF, n = 366) or vice versa (6-minute-first group, 6MF, n = 367).
Impact of 9-Minute Withdrawal Time on the Adenoma Detection Rate: A Multicenter Randomized Controlled Trial.
Clin Gastroenterol Hepatol
February 2022
Department of Gastroenterology, Changhai Hospital, Second Military Medical University/Naval Medical University, Shanghai; Digestive Endoscopy Center, Changhai Hospital, Naval/Second Military Medical University, Shanghai; National Clinical Research Center for Digestive Diseases, Shanghai; National Qu
Background & Aims: Although current quality indicators of colonoscopy recommend 6 minutes as the minimum standard for withdrawal time (WT), the impact of a WT longer than 6 minutes on neoplasia detection is unclear.
Methods: A multicenter randomized controlled trial involving 1027 patients was conducted from January 2018 to July 2019. Participants were randomly divided into a 9-minute (n = 514) and 6-minute (n = 513) WT group, and a timer was used to adjust the withdrawal speed.
Magnitude, Risk Factors, and Factors Associated With Adenoma Miss Rate of Tandem Colonoscopy: A Systematic Review and Meta-analysis.
Gastroenterology
May 2019
Department of Gastroenterology, Changhai Hospital, Second Military Medical University and Naval Medical University, Shanghai, China; Digestive Endoscopy Center, Changhai Hospital, Naval and Second Military Medical University, Shanghai, China; National Clinical Research Center for Digestive Diseases,
Background & Aims: We performed a systematic review and meta-analysis to comprehensively estimate adenoma miss rate (AMR) and advanced AMR (AAMR) and explore associated factors.
Methods: We searched the PubMed, Web of Science, and Ovid EMBASE databases for studies published through April 2018 on tandem colonoscopies, with AMR and AAMR as the primary outcomes. We performed meta-regression analyses to identify risk factors and factors associated with outcome.