Handgrip Strength Associated With Leg Strength, Power, and Muscle Mass in 18-64-Year-Old Males and Females.

McBride, JM, Bauer, EC, Kaufmann, NC, Triplett, NT, and Shanely, RA. Handgrip strength associated with leg strength, power, and muscle mass in 18-64-year-old males and females. J Strength Cond Res 39(6): 642-648, 2025-The purpose of this investigation was to determine the association between handgrip strength (HGS) and measures of leg strength, power, and muscle mass.

Effects of Nitro-Substitution on the Spectroscopic and Self-Assembly Properties of BODIPY Dyes.

A series of boron dipyrromethene (BODIPY) dyes were nitrated in high yields using nitronium tetrafluoroborate at positions 2, 3, and 2,6 of the BODIPY core. This method allows for the regioselective nitration of the pyrrolic positions under milder conditions than previously reported methods. The photophysical properties and electronic transitions of these BODIPYs were investigated by using UV-vis spectroscopy, fluorescence spectroscopy, and density-functional theory (DFT) calculations.

Selective Influence of Hemp Fiber Ingestion on Post-Exercise Gut Permeability: A Metabolomics-Based Analysis.

This study investigated the effects of 2-week ingestion of hemp fiber (high and low doses) versus placebo bars on gut permeability and plasma metabolite shifts during recovery from 2.25 h intensive cycling. Hemp hull powder is a rich source of two bioactive compounds, N-trans-caffeoyl tyramine (NCT) and N-trans-feruloyl tyramine (NFT), with potential gut health benefits.

Effectiveness of Video-Based Instruction With Additional Components to Improve Conversational Skills in Autistic Children: A Systematic Review.

Purpose: This systematic review assessed the impact of video-based instruction with additional intervention components on autistic children's conversational skills.

Method: Single-subject multiple-baseline design studies from 2000 to 2022 were included. Studies were identified through searches of six databases, other sources, and forward and backward citation tracking.

Synergies, Discrepancies, and Action Priorities: A Statewide Engagement Study to Strengthen Clinical Research in Cerebral Palsy.

Background: Cerebral palsy (CP) clinical research is fraught with challenges, in part due to health-related disparities common among people with disabilities. Perspectives of people with lived experience of CP, clinicians and researchers vary on how to address these disparities. The present initiative explores synergies and discrepancies among stakeholders (n = 212) representing these partner groups in perceived barriers and facilitators to high-quality clinical CP research and robust trainee pathways.

Phosphorus mining and bioavailability for plant acquisition: environmental sustainability perspectives.

This review aims to examine microbial mechanisms for phosphorus (P) solubilization, assess the impacts of P mining and scarcity, and advocate for sustainable recycling strategies to enhance agricultural and environmental resilience. Phosphorus is an indispensable macronutrient for plant growth and agricultural productivity, yet its bioavailability in cultivation systems is often constrained. This scarcity has led to a heavy reliance on fertilizers derived from mined phosphate rock (PR), which is a finite resource usually contaminated with hazardous elements such as uranium, radium, and thorium.

Modeling solutions for microbial water contamination in the global south for public health protection.

Microbial contamination of water sources is a pressing global challenge, disproportionately affecting developing regions with inadequate infrastructure and limited access to safe drinking water. In the Global South, waterborne pathogens such as bacteria, viruses, protozoa, and helminths contribute to diseases like cholera, dysentery, and typhoid fever, resulting in severe public health burdens. Predictive modeling emerges as a pivotal tool in addressing these challenges, offering data-driven insights to anticipate contamination events and optimize mitigation strategies.

Trend of genital ulcers and discharge and associated factors among survey respondents in Tanzania, 2004-2022: Analysis of demographic health surveys.

Introduction: Sexually transmitted infections (STIs) continue to pose a significant public health challenge worldwide, with over 1 million new cases reported daily. STI's are known to negatively impact sexual and reproductive health, increases risk of HIV transmission and acquisitions, as well as impacting mental health, personal wellbeing, and relationships. Information on the trend of STIs using nationally representative data in Tanzania is lacking.

Transcranial Direct Current Stimulation over the Motor or Frontal Cortex in Patients with Chronic Ankle Instability.

Objective: Growing evidence has suggested clinical efficacy for the use of anodal transcranial direct current stimulation (atDCS) when combined with motor interventions in patients with chronic ankle instability (CAI). However, no studies have compared multiple approaches for improving motor function with atDCS in patients with CAI. We therefore aimed to determine the efficacy of atDCS over the motor or frontal cortex when combined with a four-week motor planning intervention on neural function, performance, and patient-reported outcomes in patients with CAI.

Mapping maternity care deserts: Driving distance and health outcomes in North Carolina.

Objective: This study evaluated the association between maternal care deserts (MCDs)-defined by accessibility measures such as travel time and distance to obstetric and gynecological care-and maternal and infant health outcomes in North Carolina from 2016 to 2021.

Methods: This was a retrospective secondary data analysis examining residents of North Carolina from 2016 to 2021, using travel metrics from residential zip codes to the nearest clinical providers. Maternal and infant health outcomes were assessed using data from the National Plan and Provider Enumeration System (NPPES) from the Centers for Medicare & Medicaid Services (CMS) and inpatient hospitalization records for North Carolina.

Gut Prevotella copri abundance linked to elevated post-exercise inflammation.

Purpose: This study aimed to examine the linkage between gut microbiome taxa and exercise-induced inflammation.

Methods: Twenty-five cyclists provided 4 stool samples during a 10-week period and cycled vigorously for 2.25 h at 67% maximal oxygen uptake (VO) in a laboratory setting.

North Carolina's FarmsSHARE: Farmers, Food Hubs, And Community-Based Organizations Sustain Healthy Food Programs.

The North Carolina FarmsSHARE program distributes healthy, locally sourced food to low-income households across nearly 100 counties in the state through the Department of Agriculture's Local Food Purchase Assistance Cooperative Agreement. In this article, we present insights from a cross-sectional survey of stakeholders who were involved in implementing the program. We explore measures of satisfaction, perceived value, economic impact, quality of food, and community relationships within each stakeholder group (farmers, food hubs, and community-based organizations).

Interpersonal problems as a predictor of treatment outcome in adult depression: An individual participant data meta-analysis.

Objectives: Interpersonal problems are a fundamental feature of depression, but study-level meta-analyses of their association with treatment outcome have been limited by heterogeneity in primary studies' analyses and reported results. We conducted a pre-registered individual participant data meta-analysis (IPD-MA) to examine this relationship for adult depression. This meta-analytic strategy can reduce variability by standardizing data analysis across primary studies.

Geriatric Vulnerabilities Among Adults With Heart Failure With Preserved Ejection Fraction: A Cross-Continent Evaluation.

Background: Heart failure with preserved ejection fraction (HFpEF) disproportionately affects older adults.

Objectives: This study aimed to elucidate the prevalence and prognostic implications of geriatric vulnerabilities across multiple health domains in HFpEF.

Methods: We examined consecutive patients with HFpEF enrolled from the Weill Cornell Medicine (WCM) and the OPTIMISE HFpEF Programs.

Comparing the Resistance Training Stimuli Using Velocity Feedback or Perceived Exertion in Bench Press.

Naclerio, F, Larumbe-Zabala, E, Chapman, M, Gonzales-Frutos, P, and Triplett, NT. Comparing the resistance training stimuli using velocity feedback or perceived exertion in bench press. J Strength Cond Res 39(4): 399-406, 2025-We compared the velocity feedback method (VEL) vs.

The psychostimulant drug, fenethylline (captagon): Health risks, addiction and the global impact of illicit trade.

Fenethylline (street name, captagon) is a synthetic amphetamine-type stimulant that is emerging as a significant public health and security concern, particularly in the Middle East. This systematic review synthesizes original research articles, epidemiological studies, systematic reviews, policy analyses, and case reports to provide a comprehensive analysis of fenethylline's health impacts, addiction potential, and dynamics of illicit trade. Initially developed for therapeutic use, fenethylline illicit production and use have escalated, raising concern about its physiological, psychological, and socio-economic impacts.

Honey as a Natural Antimicrobial.

Honey, a natural product with a rich history of medicinal use, has gained increasing recognition for its potent antimicrobial properties, particularly against antibiotic-resistant pathogens. This review focuses on the antimicrobial mechanisms of honey, including its efficacy against resistant bacteria, such as Methicillin-resistant and . The antimicrobial action of honey is multifactorial, involving hydrogen peroxide production, phenolic compounds, high sugar concentrations, and the presence of bee defensin-1.

Extending the ADHD Phenotype and Parsing Heterogeneity Via Emotional Dysregulation and Personality: A Latent Profile Analysis in College Students.

Objective: Past work has provided support for the relevance of personality traits and emotional dysregulation (ED), individually, for characterizing ADHD phenotypes beyond symptoms in college-aged populations. Yet, no studies have attempted to integrate these constructs into current ADHD conceptualizations within the context of one another. The current study thus sought to determine whether personality traits and ED dimensions, together, could facilitate meaningful differentiation of college students meeting symptom and impairment criteria for ADHD.

In-person and cyber sexual violence are common in young women who have eating disordered symptoms.

This study explored the relationship between eating disordered symptoms and in-person (ISV) and cyber sexual violence (CSV) by recruiting young women ( = 145) on Prolific with current eating disordered symptoms. Having experienced some sexual violence was ubiquitous (91.7%), and 73.

Accuracy and repeatability of the COSMED® Q-NRG max mobile metabolic system.

Purpose: To investigate the accuracy and repeatability of the Q-NRG Max® metabolic system against a VacuMed metabolic simulator using a wide range of metabolic rates.

Methods: Sixteen metabolic rates (oxygen consumption 0.9-6 L/min), with different combinations of minute ventilation, oxygen consumption, and carbon dioxide production, were measured for 5 minutes, two times by a single Q-NRG Max® unit over the course of one week.

A double-edged hashtag: Evaluation of #ADHD-related TikTok content and its associations with perceptions of ADHD.

We aimed to assess the psychoeducational quality of TikTok content about attention-deficit/hyperactivity disorder (ADHD) from the perspective of both mental health professionals and young adults across two pre-registered studies. In Study 1, two clinical psychologists with expertise in ADHD evaluated the claims (accuracy, nuance, overall quality as psychoeducation material) made in the top 100 #ADHD TikTok videos. Despite the videos' immense popularity (collectively amassing nearly half a billion views), fewer than 50% of the claims about ADHD symptoms were judged to align with the Diagnostic and Statistical Manual of Mental Disorders.

Creating Interprofessional Best Practices in Education for Care of the Transgender Community using 360-Virtual Reality and Simulation.

Transgender individuals face significant health disparities, including barriers to accessing gender-affirming care. Nursing education plays a crucial role in preparing future registered nurses to deliver respectful and competent care to transgender individuals. This educational project aimed to design a series of interprofessional unfolding case study modules via 360-virtual reality and face-to-face simulations within a 4-year pre-licensure nursing curriculum to address the health inequities for the transgender community.

The transcription factor Jun is necessary for optic nerve regeneration in larval zebrafish.

Damage to the axons of the adult mammalian central nervous system (CNS) from traumatic injury or neurodegenerative diseases often results in permanent loss of function due to failure of axons to regenerate. Zebrafish, however, can express regeneration-associated genes to revert CNS neurons to a growth-competent state and regenerate damaged axons to functionality. An established model for CNS axon regeneration is optic nerve injury in zebrafish, where it was previously shown that thousands of genes are temporally expressed during the regeneration time course.

Frozen-Core Analytical Gradients within the Adiabatic Connection Random-Phase Approximation from an Extended Lagrangian.

The implementation of the frozen-core option in combination with the analytic gradient of the random-phase approximation (RPA) is reported based on a density functional theory reference determinant using resolution-of-the-identity techniques and an extended Lagrangian. The frozen-core option reduces the dimensionality of the matrices required for the RPA analytic gradient, thereby yielding a reduction in computational cost. A frozen core also reduces the size of the numerical frequency grid required for accurate treatment of the correlation contributions using Curtis-Clenshaw quadratures, leading to an additional speedup.

NEAT1 in Ovarian Cancer: A Key Regulator of Tumor Progression, Follicular Fluid Dynamics, and Therapeutic Resistance.

Nuclear enriched abundant transcript 1 (NEAT1), a long non-coding RNA (lncRNA), is a critical player in the pathogenesis and progression of ovarian cancer. Its abnormal expression in patients' follicular fluid (FF), granulosa cells, and oocytes has been linked to key processes such as cell proliferation, apoptosis, nuclear maturation, and follicle development. NEAT1's regulation of oocyte maturation and its influence on tumor dynamics and cellular communication within the FF is well-established.