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Aim: The objective of this study was to evaluate the efficacy of DIMS (Defocus Incorporated Multiple Segments) in comparison to control group (CTRL) in a wide age group of European progressive myopes (6-26 years).
Methods: In this prospective, non-randomised observational study, 78 myopes with progression myopia to -0.25 to -8.5 D and astigmatism to -0.25 to -2.25 D chose DIMS (n=54) or single vision lenses (SV) (n=24). Baseline measurements included spherical equivalent refraction (SER) and axial length (AL), evaluated at regular intervals.
Results: In participants younger than 15 years of age, slower progression of myopia (SER) (SER -0.25±0.35 D) and reduced axial elongation (0.09 ± 0.16 mm) was observed in Group 1 (DIMS) compared to Group 2 (CTRL) (SER -0.73 ± 0.57 D, AL 0.30 ± 0.20 mm), both significantly at p-value <0.05. In participants over 15 years of age, Group 3 (DIMS) exhibited minimal myopia progression (SER -0.24 ± 0.29D) and negligible axial elongation (0.00 ± 0.07 mm), Group 4 (CTRL) demonstrated more pronounced axial elongation (SER -0.20 ± 0.53D, AL 0.01 ± 0.06 mm).
Conclusion: It can be stated that the DIMS variant is 68.7% more effective in the category of subjects younger than 15 years of age in the effect on AL and 65.6% more effective in the effect on SER compared to the SV lenses. This deceleration in myopia progression is statistically significant in the under 15 age group. A statistically significant difference in the effect on SER in this age group was observed for DIMS.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12416392 | PMC |
http://dx.doi.org/10.2147/OPTH.S541232 | DOI Listing |
Clin Ophthalmol
September 2025
Faculty of Biomedical Engineering, Czech Technical University in Prague, Kladno, Czech Republic.
Aim: The objective of this study was to evaluate the efficacy of DIMS (Defocus Incorporated Multiple Segments) in comparison to control group (CTRL) in a wide age group of European progressive myopes (6-26 years).
Methods: In this prospective, non-randomised observational study, 78 myopes with progression myopia to -0.25 to -8.
Br J Ophthalmol
September 2025
Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples Federico II, Naples, Italy.
Purpose: To determine the effects of advanced spectacle lens technologies on changes in spherical equivalent of refraction (SER) and axial length (AL) elongation in slowing down the progression of myopia in children and adolescents, by synthesising data from randomised controlled trials (RCTs).
Methods: A systematic review and meta-analysis was conducted to identify all RCTs up to 27 February 2025 that compared intervention groups with myopia control lenses and control groups with standard single vision lenses (SVLs). Data from eligible studies were extracted into specially-designed data collection forms without changing the original values.
In Vivo
August 2025
Nobel Eye Institute, Taipei, Taiwan, R.O.C.;
Background/aim: This study investigated the efficiency of combined atropine (ATR) and defocus incorporated multiple segments' (DIMS) spectacle lens ATR monotherapy in controlling high myopia in children.
Patients And Methods: A retrospective cohort study was performed, enrolling patients treated with either ATR monotherapy (n=35 eyes) or a combination of ATR and DIMS lenses (n=32 eyes). The primary outcomes were the spherical equivalent refraction (SER) progression and axial length (AXL) elongation, and were measured over a one year follow up period.
Entropy (Basel)
July 2025
School of Physics and Electronics, Shandong Normal University, Jinan 250358, China.
Multi-focus image fusion (MFIF) is an image-processing method that aims to generate fully focused images by integrating source images from different focal planes. However, the defocus spread effect (DSE) often leads to blurred or jagged focus/defocus boundaries in fused images, which affects the quality of the image. To address this issue, this paper proposes a novel model that embeds the Kolmogorov-Arnold network with convolutional layers in parallel within the U-Net architecture (KCUNet).
View Article and Find Full Text PDFPLoS One
August 2025
Graphit Innovation Factory, Drobeta-Turnu Severin, Romania.
This study proposes an innovative approach for the recycling of dry wastewater sludge in the production of fired clay bricks, aiming to create environmentally friendly and cost-effective building materials. Consequently, the proposed research focuses on optimizing the thermal and mechanical properties of ceramic bricks, while incorporating sewage sludge as a pore-forming agent in brick manufacturing process. For the assessment of porosity in ceramic brick mixtures with varying volumetric proportions of ash, clay and wastewater sludge, a novel method for microscopy image analysis is proposed.
View Article and Find Full Text PDF