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Article Abstract

Aim: The objective of this study was to evaluate the efficacy of DIMS (Defocus Incorporated Multiple Segments) in comparison to control group (CTRL) in a wide age group of European progressive myopes (6-26 years).

Methods: In this prospective, non-randomised observational study, 78 myopes with progression myopia to -0.25 to -8.5 D and astigmatism to -0.25 to -2.25 D chose DIMS (n=54) or single vision lenses (SV) (n=24). Baseline measurements included spherical equivalent refraction (SER) and axial length (AL), evaluated at regular intervals.

Results: In participants younger than 15 years of age, slower progression of myopia (SER) (SER -0.25±0.35 D) and reduced axial elongation (0.09 ± 0.16 mm) was observed in Group 1 (DIMS) compared to Group 2 (CTRL) (SER -0.73 ± 0.57 D, AL 0.30 ± 0.20 mm), both significantly at p-value <0.05. In participants over 15 years of age, Group 3 (DIMS) exhibited minimal myopia progression (SER -0.24 ± 0.29D) and negligible axial elongation (0.00 ± 0.07 mm), Group 4 (CTRL) demonstrated more pronounced axial elongation (SER -0.20 ± 0.53D, AL 0.01 ± 0.06 mm).

Conclusion: It can be stated that the DIMS variant is 68.7% more effective in the category of subjects younger than 15 years of age in the effect on AL and 65.6% more effective in the effect on SER compared to the SV lenses. This deceleration in myopia progression is statistically significant in the under 15 age group. A statistically significant difference in the effect on SER in this age group was observed for DIMS.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12416392PMC
http://dx.doi.org/10.2147/OPTH.S541232DOI Listing

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