98%
921
2 minutes
20
Background: Fall risk-increasing drugs (FRIDs) increase the risks of falls, injuries, and fractures among older adults. However, limited evidence exists on how older adults perceive and manage FRID use, particularly in Indonesia.
Objective: This study developed and psychometrically evaluated a questionnaire for assessing knowledge, attitudes, and behaviors (KABs) related to FRID use (hereafter KABQ-FRID) among older adults.
Methods: KABQ-FRID was developed through a three-stage process. The first stage involved defining a conceptual framework and generating items based on a literature review, team discussions, and expert meeting. The second stage included an expert panel review and assessment of face validity. The third stage involved psychometric testing with 100 older adults receiving medications from a public health center in Surakarta City, Indonesia. Data analysis included Mokken scale analysis, confirmatory factor analysis (CFA), construct validity assessment, and reliability testing.
Results: The final KABQ-FRID comprised 21 items across 3 dimensions: knowledge (7 items), attitude (5 items), and behavior (9 items). Psychometric evaluation demonstrated acceptable scalability for all items (Loevinger's H ≥ 0.30) and strong reliability (Cronbach's α > 0.7; intraclass correlation coefficient >0.9). CFA results revealed a χ/df of 2.0, suggesting a reasonable model fit; all dimensions exhibited satisfactory loadings. Construct validity testing demonstrated strong convergent validity; 90.5 % of the items had a correlation coefficient of >0.4, and 100 % of the items had stronger correlations within their dimensions than with other constructs.
Conclusion: KABQ-FRID is a reliable and valid instrument for assessing KAB related to FRID use among community-dwelling older adults.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.sapharm.2025.08.013 | DOI Listing |
JAMA Dermatol
September 2025
Department of Population Health, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.
Importance: Increasingly, strategies to systematically detect melanomas invoke targeted approaches, whereby those at highest risk are prioritized for skin screening. Many tools exist to predict future melanoma risk, but most have limited accuracy and are potentially biased.
Objectives: To develop an improved melanoma risk prediction tool for invasive melanoma.
JAMA Netw Open
September 2025
Oncostat U1018, Institut National de la Santé et de la Recherche Médicale (INSERM), Ligue Contre le Cancer, Paris-Saclay University, Villejuif, France.
Importance: Antibiotics, steroids, and proton pump inhibitors (PPIs) are suspected to decrease the efficacy of immunotherapy.
Objective: To explore the association of comedications with overall survival (OS) in patients with advanced non-small-cell lung cancer (NSCLC).
Design, Setting, And Participants: This nationwide retrospective cohort study used target trial emulations of patients newly diagnosed with NSCLC from January 2015 to December 2022, identified from the French national health care database.
JAMA Netw Open
September 2025
School of Nursing, Capital Medical University, Beijing, China.
Importance: The efficacy of home end-of-life care in enhancing the quality of life for terminally ill patients and families has been well documented. While previous studies have explored perspectives on quality home palliative care and end-of-life care in several countries, limited knowledge exists regarding its specific components in the Chinese context.
Objective: To explore the core elements that constitute quality home end-of-life care in China.
JAMA Netw Open
September 2025
Harvard Medical School, Boston, Massachusetts.
Importance: Research in behavioral economics has demonstrated that people have irrational biases, which make them susceptible to decisional shortcuts, or heuristics. The extent to which physicians consciously might use nudges to exploit these heuristics and thereby influence their patients' decision-making is unclear. In addition, ethical questions about the conscious use of nudges in medicine persist, yet little is known about how physicians experience and perceive their use.
View Article and Find Full Text PDFJAMA Netw Open
September 2025
Division of Gastroenterology, Department of Medicine, University of California San Diego, La Jolla.
Importance: Janus kinase (JAK) inhibitors are highly effective medications for several immune-mediated inflammatory diseases (IMIDs). However, safety concerns have led to regulatory restrictions.
Objective: To compare the risk of adverse events with JAK inhibitors vs tumor necrosis factor (TNF) antagonists in patients with IMIDs in head-to-head comparative effectiveness studies.