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One-fifth of adults who receive a total knee replacement (TKR) go on to develop chronic pain. The behavioural approach taken to find a solution to pain may vary from assimilative (pursuit of analgesia) to accommodative (acceptance of pain insolubility and adoption of alternative goals). A total of 313 patients participated in a trial of an enhanced care pathway for TKR reported pain at 3 months after surgery. Participants undertook treatment as usual or treatment as usual with a new optimised support and treatment after replacement care pathway. Several pain and psychosocial outcomes (including problem-solving) were assessed. Two of the 3 problem-solving subscales moved from assimilative to accommodative over time (solving pain, acceptance of insolubility) and the overall belief in a solution decreased. Despite this shift to a more accommodative (accepting) problem-solving approach, participants reported lower meaningfulness of life over time. This reduced meaningfulness of life was associated with an increase in pain severity, interference, and reduced knee function. These interactions were not moderated by the treatment pathway to which participants were allocated. Overall, these results suggest that while patients who have pain after TKR become less determined to pursue analgesic solutions, this accommodation is not a naturally occurring positive acceptance. We discuss the possible reasons for this lack of functional and adaptive accommodation to chronic pain over the 12 months postoperative period.
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http://dx.doi.org/10.1097/j.pain.0000000000003799 | DOI Listing |
Eur J Case Rep Intern Med
August 2025
Department of General Medicine, Chiba University Hospital, Chiba, Japan.
Introduction: Restless legs syndrome (RLS) is a common sensorimotor disorder that primarily affects the lower extremities. This condition is characterized by unpleasant sensations and an irresistible urge to move the affected body regions, typically during periods of rest or at night. While RLS most commonly involves the legs, atypical variants affecting other body parts, including the arms, abdomen, face, and even the head, have increasingly been reported.
View Article and Find Full Text PDFMed Acupunct
August 2025
American TCM Association, Roseville, MN 55113, USA.
Introduction: Acupuncture has gained recognition in modern health care for its effectiveness in managing chronic pain, reducing stress, and enhancing well-being.
Discussion: Despite this, the acupuncture profession in the United States faces significant challenges, including the disconnect between education and job markets, the encroachment of other health professionals such as physical therapists, preference for medical doctors over licensed acupuncturists in medical establishments, and inconsistent entry standards that affect care quality. Fragmented regulations and public misconceptions further undermine the profession's credibility.
Med Acupunct
August 2025
Kampo Clinical Center, Hiroshima University Hospital, Hiroshima, Japan.
Background: Acupuncture and moxibustion (AM) are effective for pain relief and chronic disease management but carry risks of adverse events (AEs). Japan prioritizes AM safety, and Hiroshima University Hospital Kampo Clinical Center (HUHKCC) follows strict professional standards to ensure both safety and efficacy.
Objectives: The study analyzes AM-related AEs in Japan over the past decade, compares them with HUHKCC practices, and proposes risk mitigation strategies.
J Surg Case Rep
September 2025
Department of Pathology, Tishreen University Hospital, Lattakia, Syria.
Endometriosis is a chronic gynecological condition characterized by the presence of endometrial-like tissue outside the uterine cavity. Although commonly associated with pelvic pain and infertility, its incidental discovery during a cesarean section is rare. To our knowledge, we report the first documented case of decidualized endometriosis identified on the anterior peritoneum during an emergency cesarean section in a 28-year-old woman with only one previous cesarean delivery and no prior symptoms.
View Article and Find Full Text PDFFront Neurosci
August 2025
Department of Medicine, Georgetown University Medical Center, Washington, DC, United States.
Introduction: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and Gulf War Illness (GWI) have similar profiles of pain (nociception), visceral interoception, and tenderness (central sensitization) that may be due to dysfunction of midbrain and medulla descending antinociceptive and antiinteroceptive mechanisms. If so, then dolorimetry, a proxy for tenderness, may be correlated with subjective symptoms. The relationship with fatigue was assessed in Chronic Idiopathic Fatigue (CIF).
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