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Objective: To assess the clinical application and therapeutic efficacy of the Traditional Chinese Medical (TCM) management model among elderly individuals in a sub-health state, and to evaluate its impact on patients' quality of life (QoL).
Methods: A retrospective cohort study was conducted, analyzing clinical data from sub-health elderly patients who received care at a designated medical institution between January 2021 and December 2023. A total of 180 patients meeting the predefined inclusion criteria were recruited and stratified into two arms based on the intervention administered. The control group received routine care without specific management protocols, whereas the experimental group underwent a structured TCM management model intervention (It covers herbal therapy, acupunture, Tui Na, medical diets and teas, etc). Outcome measures, including symptomatic relief, health-related quality of life (assessed using the SF-36 scale), and patient satisfaction, were compared between the two groups to determine the intervention's efficacy.
Results: There were no significant differences in the basic information between the two groups, indicating comparability (P>0.05). The overall effective rate of treatment in the experimental group (98.89%) was significantly higher than that in the control group (51.11%). After the intervention, the SCL-90 scores of the experimental group patients (1.32±0.25, 1.65±0.45, 1.71±0.56, 1.42±0.25, 1.45±0.31, 1.23±0.34, 1.33±0.28, 1.42±0.18, 1.37±0.29) were significantly lower than those of the control group (1.89±0.32, 1.97±0.41, 1.95±0.35, 1.85±0.23, 1.78±0.27, 1.86±0.34, 1.93±0.35, 1.68±0.19, 1.67±0.28), P<0.05. The health status scores of the experimental group patients (69.25±5.96, 25.78±3.22, 1.51±0.52, 1.03±0.36, 0.95±0.12, 3.99±0.68) were significantly higher than those of the control group (65.02±6.11, 18.23±2.14, 1.11±0.23, 0.85±0.21, 0.71±0.22, 3.13±0.25). The GSES score of the experimental group was higher than that of the control group. The UCLA-LS score of the experimental group (25.22±9.14) was significantly lower than that of the control group (39.47±8.37). The SF-36 scores of the experimental group (85.14±5.14, 87.65±5.56, 79.36±4.69, 60.23±8.73, 64.25±5.14, 78.36±4.65, 66.89±5.11, 67.65±7.03) were all higher than those of the control group (58.36±6.11, 45.36±6.05, 40.35±7.11, 25.69±8.41, 33.23±5.56, 40.56±8.56, 35.21±2.25, 35.49±5.87). The LSIA score of the experimental group (15.88±1.56) was higher than that of the control group (11.03±1.13), All P<0.05.
Conclusion: The TCM management model effectively alleviates symptoms, enhances health status, and improves psychological resilience among elderly patients in a sub-health state. It significantly elevates their QoL and life satisfaction, indicating substantial potential for widespread adoption and integration into mainstream healthcare practices for geriatric sub-health populations. However, this study still has limitations that require further refinement in subsequent research.
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http://dx.doi.org/10.2147/CIA.S536976 | DOI Listing |
Physiother Theory Pract
September 2025
School of Physical Therapy and Graduate Institute of Rehabilitation Science, College of Medicine, Chang Gung University, Taoyuan, Taiwan, ROC.
Background: Knee osteoarthritis (OA) causes pain and diminishes quality of life. Backward walking exercise (BWE) has been shown to improve lower muscle strength and reduce knee adduction moment, making it a recommended intervention for knee OA rehabilitation. This study aims to evaluate the effectiveness of BWE combined with conventional rehabilitation programs on pain intensity and disability among individuals with knee OA.
View Article and Find Full Text PDFJAMA Netw Open
September 2025
Department of Psychiatry, Psychosomatics, and Psychotherapy, University of Lübeck, Lübeck, Germany.
Importance: Patients with inflammatory rheumatic diseases (IRDs) frequently experience psychological distress; however, access to psychological support remains limited.
Objective: To investigate the effectiveness of a digital psychological intervention for individuals with IRDs.
Design, Setting, And Participants: Participants aged 18 years or older were recruited across Germany between February 22 and June 4, 2024, if they had been diagnosed with rheumatoid arthritis, psoriatic arthritis, or systemic lupus erythematosus and reported psychological distress and reduced quality of life.
Clin Transl Oncol
September 2025
Ophthalmology Unit, Cannizzaro Hospital, 95126, Catania, Italy.
Antibody-drug conjugates (ADCs) represent a promising therapeutic approach in gynecologic cancers, particularly ovarian and cervical malignancies. Agents such as mirvetuximab soravtansine, and tisotumab vedotin, targeting folate receptor alpha and tissue factor, respectively, reported clinical efficacy in patients with limited options. However, their use is associated with ocular toxicities, including keratopathy, blurred vision, and dry eye, which may impact adherence and quality of life.
View Article and Find Full Text PDFPharmacoecon Open
September 2025
Department of Pharmacy, The Second Affiliated Hospital of Army Medical University, No.83 Xinqiao Central Street, Shapingba District, Chongqing, 400037, China.
Objective: Two vaccines against herpes zoster (HZ) are currently authorized for use in China: the adjuvanted recombinant zoster vaccine (RZV) and live-attenuated Zoster Vaccine Live (ZVL). The significant disparities in prices and efficacy between the two vaccines necessitate an evaluation of their relative value in order to make an informed choice. This study aimed to evaluate the comparative cost effectiveness of RZV, ZVL, and no vaccination for older adults at different ages from the societal perspective.
View Article and Find Full Text PDFActa Neurol Belg
September 2025
Neuroscience Research Australia, University of New South Wales, Sydney, Australia.
Objectives: Patients diagnosed with amyotrophic lateral sclerosis (ALS) typically describe symptoms of fatigue. Despite this frequency, the underlying mechanisms of fatigue are poorly understood, and are likely multifactorial. To help clarify mechanisms, the present systematic review was undertaken to determine the risk factors related to fatigue in ALS.
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