98%
921
2 minutes
20
Fenugreek seeds ( L.) are known for their impressive range of health benefits, thanks to their diverse array of phytochemicals. These include steroidal sapogenins like diosgenin, alkaloids such as trigonelline, as well as flavonoids, saponins, galactomannans, and polyphenols. seeds contain mucilaginous fiber, which will tie bile acids and lower fat absorption and cholesterol. These bioactive constituents contribute to fenugreek's antioxidant, anti-inflammatory, antinociceptive, antidiabetic, hypocholesterolemic, gastroprotective, antirheumatic, and antimicrobial activities. Alkaloids, 4-Hydroxyisoleucine, and steroidal saponins have been shown to improve glucose metabolism and reduce cholesterol absorption. Additionally, specific chemical elements might excite insulin release from the B-cells directly, resulting in a drop in blood glucose levels. L. has also been found to have gastroprotective properties, antibacterial activities, and anticancer properties, and has been used to cure arthritis, lose weight, increase milk supply, and manage hyperthyroidism. Overall, fenugreek seeds represent a multi-target natural agent with significant potential for managing metabolic disorders, inflammation, and related health conditions. Therefore, this paper aims to present the existing knowledge on the nutritional composition, bioactive potential, and health benefits in detail.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12411738 | PMC |
http://dx.doi.org/10.1002/fsn3.70887 | DOI Listing |
J Am Assoc Lab Anim Sci
March 2025
Animal Resources Center, Department of Surgery, University of Chicago, Chicago, Illinois; and.
The Guide for the Care and Use of Laboratory Animals provides recommendations on sanitation frequencies for rodent caging equipment; however, it allows for performance standards to be used when extending this frequency for individually ventilated cage (IVC) caging. Our institution wanted to reexamine our current standards of care for mouse IVC caging, which includes a 14-d cage bottom and bedding change as well as the use of corncob bedding. This was driven by desire to reduce the stress to mice associated with cage change, and by recent literature showing a potential improved absorbency and multiple health and welfare benefits of paper pulp cellulose bedding products.
View Article and Find Full Text PDFStroke
September 2025
Department of Neurology, Yale School of Medicine, New Haven, CT (L.H.S.).
Preclinical stroke research faces a critical translational gap, with animal studies failing to reliably predict clinical efficacy. To address this, the field is moving toward rigorous, multicenter preclinical randomized controlled trials (mpRCTs) that mimic phase 3 clinical trials in several key components. This collective statement, derived from experts involved in mpRCTs, outlines considerations for designing and executing such trials.
View Article and Find Full Text PDFJ Paediatr Child Health
September 2025
Federal University of Juiz de Fora, Juiz de Fora, Brazil.
Aim: To measure the prevalence of BF amongst Brazilian children aged 12-24 months, assess associated social determinants and evaluate the impact of maternal knowledge about its benefits.
Methods: A cross-sectional study was conducted between September and December 2024, using an online questionnaire completed by Brazilian mothers with children aged 12-24 months. Sociodemographic data were collected, including maternal and child age, education level, marital status, ethnicity, household income and employment status.
Expert Rev Med Devices
September 2025
Department of Physical Medicine and Rehabilitation, Sanjay Gandhi Post Graduate Institute of Medical Sciences (SGPGIMS), Rae Bareli Road, Lucknow, Uttar Pradesh, INDIA 226014.
Introduction: The World Health Organization (WHO) reported in 2023 that approximately 1.3 billion people, or 16% of the global population, are living with a disability. Among these, locomotor disabilities constitute a significant portion, underscoring the urgent need for devices that enhance mobility and support daily living.
View Article and Find Full Text PDFJ Dent Educ
September 2025
College of Dentistry, Health Sciences Center, University of Oklahoma, Oklahoma City, Oklahoma, USA.
Purpose: Uganda faces significant oral health workforce shortages, limiting access to dental care. The Uganda Christian University School of Dentistry (UCUSoD) implemented a blended learning approach to enhance dental education by integrating online training. This qualitative study assesses the feasibility and effectiveness of hybrid learning in improving students' knowledge and preparedness for clinical practice.
View Article and Find Full Text PDF