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Background: Policymakers face challenges in developing pricing policies for potentially innovative healthcare technologies (pIHTs) that balance limited budgets, access, and incentives for innovation. This study aimed to map existing evidence and identify knowledge gaps regarding price determinants and pricing policies for pIHTs and their effect on access and sustainability.
Methods: We conducted a scoping Review of scientific and grey literature in English published between 2014 and September 2023 with pre-specified inclusion and exclusion criteria to identify stakeholder-informed price determinants, pricing policies applied by European Economic Area (EEA) or Organisation for Economic Cooperation and Development (OECD) member states, and their access-related impacts. Literature databases and various stakeholder organisation websites were searched. Further records were included through snowballing and manual addition.
Results: 135 Records were included. Stakeholder views on price determinants were available from 15 records and predominantly involved value-based determinants. Pricing policies in EEA/OECD member states are heterogeneous and often feature a mix of policy interventions and implementation methods. External price referencing (EPR), while yielding short-term affordability improvements, is associated with price inequities and launch strategies impairing patient access. Policies combining pricing methods and considering a pIHT's value have more positive access-related impact but may face feasibility and implementation challenges. Two records mentioned medical device pricing; none featured environmental aspects.
Conclusion: While EPR is commonly applied across Europe, value-informed pricing in connection with health technology assessment is more favoured regarding pIHT access in the literature. Knowledge gaps concern medical device pricing, stakeholder views on price determinants, and the implementation of environmental aspects in pIHT pricing.
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http://dx.doi.org/10.1007/s10198-025-01834-y | DOI Listing |
J Dent Educ
September 2025
Department of Oral and Maxillofacial Surgery, Stomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou, P. R. China.
Background: Virtual reality (VR) and artificial intelligence (AI) technologies have advanced significantly over the past few decades, expanding into various fields, including dental education.
Purpose: To comprehensively review the application of VR and AI technologies in dentistry training, focusing on their impact on cognitive load management and skill enhancement. This study systematically summarizes the existing literature by means of a scoping review to explore the effects of the application of these technologies and to explore future directions.
Pestic Biochem Physiol
November 2025
State Key Laboratory of Crop Stress Biology for Arid Areas, Northwest A&F University, Yangling 712100, Shaanxi, China; Key Laboratory for Botanical Pesticide R&D of Shaanxi Province, Yangling 712100, Shaanxi, China. Electronic address:
The beet armyworm, Spodoptera exigua has developed resistance to the commonly used insecticide indoxacarb. Understanding fitness costs and resistance mechanisms to indoxacarb in S. exigua is essential for developing effective field resistance management strategies.
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September 2025
Department of Neurosurgery, St. Marianna University School of Medicine, Kawasaki, Japan. Electronic address:
Although subdural drain (SDD) placement reduces recurrence after burr-hole surgery for chronic subdural hematoma (CSDH), complications have led our institution to discontinue its routine use. During the first year following this change, the recurrence rate was 14.6%, comparable to the recurrence rate observed prior to discontinuation.
View Article and Find Full Text PDFEnviron Res
September 2025
Department of Chemical Engineering and Biotechnology, National Taipei University of Technology, Taipei 10608, Taiwan; High-value Biomaterials Research and Commercialization Center, National Taipei University of Technology, Taipei 10608, Taiwan. Electronic address:
The persistent presence of the pharmaceutical pollutant nilutamide (NLT) in environmental and biological systems poses a serious threat to ecosystems and human health, necessitating efficient and sustainable detection strategies. In this study, we present a nanoengineered SrWO@MXene electrocatalyst as a high-performance platform for electrochemical sensing. The hybrid material seamlessly integrates the catalytic activity and electrochemical stability of SrWO with the exceptional conductivity and tunable surface chemistry of MXenes, resulting in a synergistic architecture optimized for rapid and selective NLT detection.
View Article and Find Full Text PDFActa Psychol (Amst)
September 2025
Minnan Normal University, China. Electronic address:
In the context of China's collectivist culture, this study examines how parental educational support influences the academic self-efficacy of middle school students (ages 13-16) in Fujian Province. Drawing on ecological systems theory, achievement emotion theory, and self-determination theory, the research situates parental support within the microsystem, teacher support in the mesosystem, and enjoyment as an achievement emotion bridging external support and students' internal beliefs. A dual-mediation model was tested using structural equation modeling with data from 507 students.
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