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Background: Soft-tissue filler injection-related vascular complications (IRVC) can lead to tissue necrosis, vision loss, and stroke. Hyaluronidase-based injections are the mainstay of treatment, though other options include heat, massage, nitroglycerin, and anticoagulants. Given the narrow therapeutic window and limited early warning signs, we propose training residents to implement a standardized soft-tissue filler vascular complication (SFVC) management protocol.
Objective: This study aims to address gaps in procedural knowledge by providing residents with a lecture series followed by a hands-on cadaveric practice session.
Methods And Materials: An SFVC management protocol was developed based upon a literature review and expert opinion. Didactic instruction and practice sessions with cadavers were conducted with residents at an academic dermatology program. All resident trainees took a survey assessing their knowledge and satisfaction with the quality of training.
Results: Thirteen residents were included in this study. Overall, the aggregate confidence score for recognizing vascular events, acute management of filler complications, and performance of procedures after hands-on simulation on cadavers significantly increased between pre- and post-surveys (P<0.001).
Conclusion: Our intervention successfully demonstrated increased confidence among residents regarding the key components of SFVC, namely, in recognizing the signs and symptoms, managing an acute event, and finally, in performing advanced procedures for SFVC.
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http://dx.doi.org/10.36849/jdd.8039 | DOI Listing |
Hum Brain Mapp
September 2025
Department of Pediatrics, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Perinatal stroke is a vascular injury occurring early in life, often resulting in motor deficits (hemiplegic cerebral palsy/HCP). Comorbidities may also include poor neuropsychological outcomes, such as deficits in memory. Previous studies have used resting state functional MRI (fMRI) to demonstrate that functional connectivity (FC) within hippocampal circuits is associated with memory function in typically developing controls (TDC) and in adults after stroke, but this is unexplored in perinatal stroke.
View Article and Find Full Text PDFMultimed Man Cardiothorac Surg
September 2025
Kawasaki Aortic Center, Kawasaki Saiwai Hospital, Kawasaki, Japan.
Kommerell's diverticulum (KD) combined with a right-sided aortic arch (RAA) and an aberrant left subclavian artery (ALSA) is a rare congenital vascular anomaly causing significant compressive dysphagia. Treatment options, including open surgery, thoracic endovascular aortic repair and hybrid approaches, are debated due to anatomical complexities. We report a 48-year-old female with dysphagia from symptomatic KD, RAA and ALSA, clearly delineated by preoperative computed tomography angiography.
View Article and Find Full Text PDFMultimed Man Cardiothorac Surg
September 2025
Department of Cardiovascular Surgery, Marmara University Pendik Research and Training Hospital, Istanbul, Turkey.
Complete detachment of the aortic root following a Bentall procedure is an exceptionally rare complication. The vast majority of reported cases are secondary to prosthetic valve endocarditis or underlying vasculitis. Currently, the most reliable treatment for aortic root dehiscence-particularly in the context of prosthetic valve endocarditis-is repeat root replacement, typically via a second Bentall procedure or with the use of a homograft or allograft.
View Article and Find Full Text PDFDiabetes Metab J
September 2025
Department of Vascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Background: Diabetic foot ulcer (DFU) represents a challenging complication of diabetes mellitus, characterized by slow healing processes. Protein kinase C delta (PKCδ) has been identified as a significant factor in the pathogenesis of various diabetic complications, including DFU. However, the precise underlying mechanisms remain to be fully elucidated.
View Article and Find Full Text PDFClin Anat
September 2025
Department of Otorhinolaryngology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
There are no standardized guidelines for reconstructive surgery of large temporal bone defects following lateral temporal bone resection for external auditory (acoustic) meatus carcinoma. Filling the defect with well-vascularized tissue is important for large tissue defects to promote wound healing and prevent infection postoperatively. Patients with malignant tumors of the external acoustic meatus requiring lateral temporal bone resection may sometimes necessitate postoperative adjuvant chemoradiotherapy.
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