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Article Abstract

Introduction: Primary squamous cell carcinoma of the prostate accounts for < 1% of prostate cancers.

Case Presentation: A 70-year-old man with no urinary symptoms and a normal prostate-specific antigen of 0.96 ng/mL was referred for abnormal prostate uptake on positron emission tomography-computed tomography. He was diagnosed with locally advanced squamous cell carcinoma of the prostate with lymph node metastasis. Robot-assisted radical prostatectomy and adjuvant chemoradiotherapy were administered. The patient remained in complete remission at 18 months postoperatively.

Conclusion: Squamous cell carcinoma of the prostate should be suspected based on positron emission tomography-computed tomography prostate uptake. Robot-assisted radical prostatectomy may be feasible for locally advanced squamous cell carcinoma of the prostate; genetic profiling should be considered to identify targeted therapies.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12408172PMC
http://dx.doi.org/10.1002/iju5.70088DOI Listing

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