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Splenic abscesses are rare but potentially fatal infections, particularly in individuals with diabetes mellitus. Management strategies vary based on the abscess size, complexity, and response to the initial treatment. We report five patients with diabetes and splenic abscesses who were managed at a tertiary care centre. All patients presented with left upper quadrant pain, fever, and leukocytosis. The diagnosis was confirmed via ultrasonography and contrast-enhanced computed tomography. One patient was managed conservatively with antibiotic therapy. Two patients underwent successful image-guided pigtail drainage, while one required splenectomy due to persistent infection. The remaining two patients underwent direct open splenectomy due to large loculated abscesses or lack of clinical improvement. The cultured isolates included and species, and all patients recovered well. A tailored, stepwise approach to splenic abscesses, beginning with imaging, followed by medical or minimally invasive management, and escalating to surgery when necessary, yields favourable outcomes.
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http://dx.doi.org/10.7759/cureus.89325 | DOI Listing |
Ann Surg Oncol
September 2025
Hepato‑Biliary and Pancreatic Surgery Unit, Department of Surgery, Hospital del Mar, Pompeu Fabra University, Barcelona, Spain.
Background: Spleen-preserving distal pancreatectomy by robotic surgery is a safe and feasible surgical technique. Currently, spleen-preserving distal pancreatectomy represents an alternative to the classical distal pancreatectomy with splenectomy, in the case of benign and low-grade malignant diseases of the body or pancreas tail. The reasons for preserving the spleen are based on the reduction of postoperative complications, such as post-splenectomy infections, subphrenic abscess, portal thrombosis, pulmonary hypertension, thrombocytosis, and thromboembolism.
View Article and Find Full Text PDFCureus
August 2025
Interventional Radiology, Sacred Heart Hospital, Pensacola, USA.
Transjugular intrahepatic portosystemic shunt (TIPS) placement is a well-established intervention for portal hypertension. However, some patients experience persistent complications such as encephalopathy, ascites, or thrombocytopenia, especially when further TIPS optimization is not technically possible. Partial splenic embolization (PSE), typically performed for hypersplenism or certain hematologic conditions, can reduce portal venous inflow and improve cytopenias; however, its use as an adjunct to TIPS is less well described.
View Article and Find Full Text PDFInfect Disord Drug Targets
September 2025
Department of Chemistry, NFC Institute of Technology, Multan, Pakistan.
Introduction: Targeted infection imaging is crucial for accurate diagnosis in postpartum women. This project uses 99mTc-labeled cefixime to develop a radiopharmaceutical for detecting, distinguishing, and treating infections and abscesses in women.
Method: Technetium (TcO4-) chelated with cefixime, reduced by stannous chloride, confirmed via thin-layer chromatography.
Front Oncol
August 2025
Department of Ultrasound, The Second Affiliated Hospital of Dalian Medical University, Dalian, China.
Gastrosplenic fistula is a rare complication, most often secondary to gastric or splenic lymphoma. Severe gastrosplenic fistula can cause life-threatening upper gastrointestinal bleeding, making early diagnosis and intervention critical for a favorable prognosis. Currently, surgical intervention remains the primary treatment; however, outcomes are often suboptimal.
View Article and Find Full Text PDFCureus
August 2025
General Surgery, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Splenic abscesses are rare but potentially fatal infections, particularly in individuals with diabetes mellitus. Management strategies vary based on the abscess size, complexity, and response to the initial treatment. We report five patients with diabetes and splenic abscesses who were managed at a tertiary care centre.
View Article and Find Full Text PDF