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http://dx.doi.org/10.3341/kjo.2025.0115 | DOI Listing |
ACS Biomater Sci Eng
September 2025
University Center for Research & Development (UCRD), Chandigarh University, NH-05 Chandigarh-Ludhiana Highway, Mohali 140413, Punjab, India.
Cardiovascular disorders remain a leading cause of death worldwide, and the use of contemporary stents is paving the way for a profound shift in the field of cardiology. In the surgical process postimplantation, the graft or stent and host-immune interaction play a significant role in the healing process, thus it is a major challenge in healthcare. To address these challenges, recent advancements have introduced bioactive coatings with specialized modifications in stents to enhance their interaction with surrounding environment.
View Article and Find Full Text PDFEur J Ophthalmol
September 2025
vEyes NPO, vEyes Lab, Milo, Italy.
PurposeTo introduce, describe and validate a novel, 3D-printed portable slit lamp system integrated with a macro lens-equipped smartphone, providing clinicians with a quick, easy, and effective method for obtaining high-quality clinical images.Materials and MethodsA 3D-printed portable slit lamp was developed, comprising a warm white LED light pen housed in a custom case with a biconvex lens focusing light through a 0.4 mm slit.
View Article and Find Full Text PDFCrit Rev Food Sci Nutr
September 2025
State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, P. R. China.
Natural products have emerged as a vital source of active ingredients in medicine, food, and cosmetics due to their unique biological activities, safety profiles, and sustainability. However, most bioactive compounds in natural products are intensely bitter, limiting their use in pharmaceuticals and foods. The bitter taste attributes vary markedly among different compound classes, predominantly due to their structural characteristics.
View Article and Find Full Text PDFACS Synth Biol
September 2025
Engineering Research Center of Western Resource Innovation Medicine Green Manufacturing, Ministry of Education, School of Chemical Engineering, Northwest University, Xi'an 710127, China.
The environmental resistance exhibited by microorganisms is concerned with their ability to withstand and adapt to an array of detrimental environmental conditions, with their survival and reproductive success being threatened. Within the realm of biotechnology, which emphasizes stress resistance, a critical role in bacterial adaptive strategies to environmental fluctuations is assumed to be in the periplasmic space. An innovative methodology to augment bacterial tolerance to stress by employing a mucin-mimetic collagen analogue, designated as S1552 (which is secreted into the periplasmic compartment), is introduced by this investigation.
View Article and Find Full Text PDFACS Appl Mater Interfaces
September 2025
Faculty of Chemistry, Jagiellonian University, Gronostajowa 2, Kraków 30-387, Poland.
The multifunctional systems presented here introduce an innovative and deeply thought-out approach to the more effective and safer use of temozolomide (TMZ) in treating glioma. The developed hydrogel-based flakes were designed to address the issues of local GBL therapy, bacterial neuroinfections, and the bleeding control needed during tumor resection. The materials obtained comprise TMZ and vancomycin (VANC) loaded into cyclodextrin/polymeric capsules and embedded into gelatin/hyaluronic acid/chitosan-based hydrogel films cross-linked with genipin.
View Article and Find Full Text PDF