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Intravenous smart pump alarm fatigue remains a persistent and underrecognized patient safety concern in acute and critical care settings. Although alarm fatigue has been traditionally associated with physiological monitors, intravenous smart pumps are also a frequent source of alarms for hospitalized patients that contribute substantially to alarm fatigue. This article synthesizes current evidence on intravenous smart pumps and related alarm fatigue, identifies knowledge gaps, and proposes short-term and long-term interventions. Inconsistencies in alarm design and inadequate human-centered design have led to the development of intravenous smart pump systems that create an unacceptably high number of technical alarms that are unrelated to changes in patient status. Data-driven strategies are discussed as mechanisms to reduce burden and enhance alarm effectiveness. A systems-level approach combining human factors engineering, intelligent algorithm development, and clinical partnerships with manufacturers is essential for reducing alarm-related risk, decreasing nursing workload, and improving patient outcomes.
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http://dx.doi.org/10.4037/aacnacc2025136 | DOI Listing |
J Appl Physiol (1985)
September 2025
Department of Human Physiology and Nutrition, William J. Hybl Sport Medicine and Performance Center, University of Colorado Colorado Springs, Colorado Springs, CO, USA.
Chronic exposure to high altitude leads to increases in hemoglobin mass (Hbmass), which may improve exercise performance and decrease acute mountain sickness (AMS) symptoms. We evaluated the influence of intravenous iron or erythropoietin (EPO) treatment on Hbmass, exercise performance, and AMS during a 14-day exposure to 3094 m. Thirty-nine participants (12F) completed the study conducted in Eugene, Oregon (sea level (SL), 130 m) and Leadville, Colorado (3094 m).
View Article and Find Full Text PDFBiomaterials
September 2025
Department of Radiology, Fifth Hospital of Shanxi Medical University, Shanxi Provincial People's Hospital, Taiyuan, 030000, China. Electronic address:
Acute liver injury (ALI) is a serious disease characterized by liver function impairment caused by multiple causes in a short period of time. Due to lack of precise diagnosis and timely intervention, many patients with ALI rapidly progress to liver dysfunction and liver failure. Here, a multifunctional silybin nano-prodrug, PTS@IR, was developed that integrated microenvironment-activatable second near-infrared (NIR-II) fluorescence (FL) imaging for precise diagnosis and timely therapy of ALI.
View Article and Find Full Text PDFAACN Adv Crit Care
September 2025
Nathaniel M. Sims is Research Faculty, Department of Anesthesia, Mass General Brigham (MGB). Associate Professor, Harvard Medical School. Newbower/Eitan MGH Endowed Chair in Biomedical Technology Innovation. Physician Advisor, MGB Biomedical Engineering, Boston, Massachusetts.
Secondary medication delivery using large-volume smart pumps offers important workflow and safety benefits. However, the widely used linear peristaltic large-volume smart pumps rely on sufficient head-height differential for accurate secondary infusion, leading to underdelivery risks. This article outlines common clinician workarounds used to mitigate these risks, including delivering secondary medications via primary mode, programming excess volume to be infused, clamping primary lines, and using short-set primary delivery.
View Article and Find Full Text PDFAACN Adv Crit Care
September 2025
Karen K. Giuliano is Professor, Institute for Applied Life Sciences and Elaine Marieb College of Nursing, and Codirector, Elaine Marieb Center for Nursing and Engineering Innovation, University of Massachusetts Amherst, Amherst, Massachusetts.
Intravenous smart pump alarm fatigue remains a persistent and underrecognized patient safety concern in acute and critical care settings. Although alarm fatigue has been traditionally associated with physiological monitors, intravenous smart pumps are also a frequent source of alarms for hospitalized patients that contribute substantially to alarm fatigue. This article synthesizes current evidence on intravenous smart pumps and related alarm fatigue, identifies knowledge gaps, and proposes short-term and long-term interventions.
View Article and Find Full Text PDFAACN Adv Crit Care
September 2025
Dian Baker is Professor Emeritus, School of Nursing, California State University, Sacramento, California.
Large-volume intravenous (IV) smart pumps are used in acute and critical care to deliver IV fluids and medications with safety-enhancing features such as dose error reduction systems. Although these technologies offer improvements over manual administration, IV smart pumps are associated with high rates of medication errors, programming challenges, and usability issues. Alarm fatigue, interface complexity, and workarounds are common, with studies showing high error rates.
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