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(GBS) is a rare cause of meningitis in healthy adults. We report the case of a healthy 33-year-old man with acute GBS meningitis who experienced relapsed high-grade fever and increased intracranial pressure following completing intravenous antibiotics. A short course of corticosteroids, along with additional antibiotics, improved the cerebrospinal fluid (CSF) profile, and no further complications occurred after the recurrent episodes. The study highlights the need to consider significant CSF inflammation and potential neurological complications in acute GBS meningitis patients, even in the absence of immunodeficiency or previous surgeries. One of the possible routes of infection in our case was suspected from a history of nasal mucosal damage. The importance of careful monitoring and treatment adjustments should be performed and correlated with clinical signs and symptoms.
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http://dx.doi.org/10.1002/jgf2.70039 | DOI Listing |
J Gen Fam Med
September 2025
Chakri Naruebodindra Medical Institute, Faculty of Medicine Ramathibodi Hospital Mahidol University Samut Prakan Thailand.
(GBS) is a rare cause of meningitis in healthy adults. We report the case of a healthy 33-year-old man with acute GBS meningitis who experienced relapsed high-grade fever and increased intracranial pressure following completing intravenous antibiotics. A short course of corticosteroids, along with additional antibiotics, improved the cerebrospinal fluid (CSF) profile, and no further complications occurred after the recurrent episodes.
View Article and Find Full Text PDFJ Pediatr
August 2025
Arctic Investigations Program, Division of Infectious Disease Readiness and Innovation, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Anchorage, Alaska, USA;. Electronic address:
Objective: Our objective was to compare the clinical course of invasive Haemophilus influenzae disease by type among children at 2 hospitals in Alaska.
Study Design: We performed a retrospective review of invasive H. influenzae cases among Alaska children aged <10 years who received care at the Alaska Native Medical Center in Anchorage or the Yukon-Kuskokwim Delta Regional Hospital in Bethel, Alaska, during 2013-2019.
Neurol Sci
August 2025
Department of Neurology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221005, Uttar Pradesh, India.
Purpose: Tuberculous meningitis (TBM), a severe and often fatal form of tuberculosis, showing high mortality and long-term neurological sequelae. Recent evidence suggests that microRNAs play a crucial role in TBM pathogenesis and may serve as potential biomarkers for diagnosis and disease progression.
Methods: Eight TBM patients and three healthy controls were recruited.
Front Med (Lausanne)
August 2025
Department of Neurology, Puer People's Hospital, Pu'er, China.
Background: Varicella zoster virus (VZV) infection during pregnancy can lead to severe complications. However, cases complicated by aseptic meningitis in early pregnancy (<20 weeks) are extremely rare, and clinical management and pregnancy outcomes remain unclear.
Case Report: We report a case of a 36-year-old pregnant woman who developed right upper abdominal pain, headache, and cough at 17 weeks of gestation, followed by clustered herpes zoster lesions in the right lumbar region and signs of meningeal irritation.
Eur J Med Res
August 2025
Fuzong Clinical Medical College of Fujian Medical University, Fuzhou, 350025, Fujian, China.
Background: The role of intracranial lymphatic circulation in Parkinson's disease (PD) causes more and more concerns nowadays. The drainage function of meningeal lymphatic vessels (MLVs) and the clearance capability of the glymphatic system have been demonstrated to associate with development of PD. However, the underlying mechanisms remain inadequately elucidated.
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