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Objective: Much of the literature that examines well-being in parent caregivers of children with chronic conditions addresses psychosocial correlates. Yet, few studies address an integral cognitive aspect of daily life, prospective memory (PM), in association with parent well-being. The present work addressed this gap and examined parents' self-reported PM demands related to managing their child's chronic conditions and frequency of PM forgetting to well-being.
Methods: A sample of 149 parents of children with chronic conditions completed an online survey including measures of parent and family demographics, PM demands, PM forgetting, perceptions of parenting self-efficacy, and well-being: depressive symptoms, anxious symptoms, general stress, and parenting-related stress. Hierarchical regression analyses evaluated the unique contributions of PM demands and forgetting to each well-being outcome over-and-above other known demographic correlates and perceptions of parenting self-efficacy.
Results: Analyses suggested that PM experiences, particularly forgetting, explained a significantly greater proportion of variance in each well-being outcome beyond the demographic factors and perceptions of parenting self-efficacy. Additionally, exploratory analyses revealed that there was an indirect effect of PM forgetting on each wellbeing outcome via self-efficacy, suggesting that greater confidence in one's parenting may explain the link between perceived forgetfulness and detriments to well-being.
Conclusion: The present work adds to the literature by documenting the unique effects of everyday cognitive experiences (PM demands and forgetting) in relation to parent caregiver well-being. These findings have important implications for possible interventions to improve caregivers' everyday remembering and well-being.
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http://dx.doi.org/10.1093/jpepsy/jsaf077 | DOI Listing |
Pediatr Blood Cancer
September 2025
Acute Myeloid Leukemia Sub-Committee, Association of Childhood Leukemia Study (JACLS), Japan.
Background: Relapsed or refractory cases of pediatric acute myeloid leukemia (AML) have poor outcomes despite advancements in chemotherapy and hematopoietic stem cell transplantation (HSCT). While a second HSCT is often a salvage option, its outcomes vary widely, and prognostic factors remain unclear.
Objectives: This study aimed to evaluate outcomes and identify prognostic factors in pediatric patients with AML who underwent multiple HSCTs.
Pediatr Blood Cancer
September 2025
Department of Pediatrics, Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta and Emory University, Atlanta, Georgia, USA.
Moyamoya syndrome (MMS) is a chronic vasculopathy characterized by progressive stenosis of intracerebral arteries, leading to an increased risk of stroke. Children with Down syndrome (DS) are at an increased risk of co-occurring medical conditions, including MMS and leukemia. We report four patients with the triad of DS, MMS, and acute lymphoblastic leukemia (ALL).
View Article and Find Full Text PDFEur J Oral Sci
September 2025
State Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Research Unit of Oral Carcinogenesis and Management, Chinese Academy of Medical Sciences, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, People's Re
Oral lichen planus (OLP) is a chronic inflammatory disease of unknown aetiology, which is an oral potentially malignant disorder. Many investigators suggest that OLP may be a localized autoimmune response caused by cell-mediated autoimmunity to basal cells. However, it remains unclear whether allergens play a role in the pathogenesis of OLP.
View Article and Find Full Text PDFSemin Dial
September 2025
Department of Nephrology, Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital, New Delhi, India.
Background: In hyponatremic patients, concurrent dialysate flow during hemodialysis may be an ideal option to mitigate complications such as osmotic demyelination syndrome (ODS).
Methods: Present randomized controlled trial enrolled dialysis-requiring chronic kidney disease (CKD) and acute kidney injury (AKI) patients with serum sodium levels < 125 mEq/L during January 2020 over 16 months. Hemodynamically unstable patients, as well as those with a history of seizures and neurological conditions, were excluded.
Immunol Invest
September 2025
Department of Function, Affiliated Wuxi Fifth Hospital of Jiangnan University, Wuxi, China.
Objective: This study aims to elucidate how butyrate, a short-chain fatty acid, regulates the Treg/Th17 balance in ulcerative colitis (UC) via the cAMP-PKA/mTOR signaling pathway, offering novel treatment strategies.
Methods: Dextran sulfate sodium (DSS) was used to induce ulcerative colitis in a mouse model. Various butyrate dosages were administered to the mice.