Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Dystocia due to developmental disorders causing foetal malformation is a significant challenge in bovine obstetrics, often resulting in severe birth complications. This narrative review provides an updated overview of the most common congenital syndromes associated with dystocia in cattle, emphasising both their clinical implications and underlying causes. Congenital disorders such as schistosoma reflexum, perosomus elumbis, arthrogryposis, hydrocephalus, anasarca and embryonic duplication are reviewed in detail, along with their impact on the course of calving. While the management of dystocia due to foetal malformations has remained relatively constant over time-mainly involving assisted delivery, foetotomy or caesarean section-our understanding of their aetiologies has advanced considerably. In addition to environmental factors, such as viral infections during gestation, genetic causes may also be implicated. Genetic aetiologies, including dominant de novo mutations and recessively inherited alleles, such as single nucleotide variants, larger structural variants or aneuploidies, have been identified as the cause of some of these congenital defects. This review provides a comprehensive resource on dystocia due to developmental disorders, offering veterinarians updated knowledge to guide clinical decision making and improve outcomes for both the dam and the calf.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12406085 | PMC |
| http://dx.doi.org/10.1111/rda.70083 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Challenges, benefits, and strategies for delivering pregnancy care to people with disabilities: A qualitative study of service providers and decision-makers in Ontario, Canada.
J Health Serv Res Policy
September 2025
Department of Health and Society, University of Toronto Scarborough, Toronto, ON, Canada.
ObjectivesTo (1) understand the challenges and benefits of providing pregnancy care to people with disabilities and (2) identify strategies to address challenges, from the perspectives of health care and social service providers and decision-makers.MethodsWe undertook a qualitative descriptive study in Ontario, Canada, of 31 health care and social service providers and decision-makers. Participants completed semi-structured interviews about their education, training, and clinical or administrative experience working with pregnant and/or parenting people with physical, sensory, and intellectual or developmental disabilities, including challenges and benefits in pregnancy care provision, programming, and policies, as well as their recommendations to improve care.
View Article and Find Full Text PDFMammalian motile cilia: Structure, formation, organization, and function.
Semin Cell Dev Biol
September 2025
Key Laboratory of Multi-Cell Systems, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, 320 Yueyang Road, Shanghai 200031, China. Electronic address:
Cilia are membrane-covered hair-like organelles built on specialized centrioles and conserved throughout eukaryotic evolution. They are either motile or immotile, serving respectively as versatile signaling antennae or elegant beating nanomachines. Accordingly, their dysfunctions cause a wide variety of developmental and degenerative disorders, which in human are syndromes termed ciliopathies.
View Article and Find Full Text PDFSteering Axon Development: Glial Cell Mechanisms in .
ACS Chem Neurosci
September 2025
School of Life Science and Technology, Key Laboratory of Developmental Genes and Human Disease, Southeast University, Nanjing 210096, China.
Glial cells play an indispensable role in the nervous system, providing structural support to neurons and regulating their function and development. Glia support neural network formation and plasticity in axon guidance, synaptic pruning, and neurogenesis. Of note, studies have shown that glial cell dysfunction is closely related to the occurrence of neurological diseases.
View Article and Find Full Text PDFMouse Model of Prenatal Valproic Acid Exposure: Effects on Cortical Morphogenesis and Behavioral Outcomes Across Environmental Conditions.
Toxicol Lett
September 2025
Mammalian Embryology, Department of Life Science, Faculty of Science and Engineering, Kindai University 3-4-1, Kowake, Higashiosaka, Osaka 577-8501, Japan. Electronic address:
Autism spectrum disorder (ASD) is a developmental disability characterized by impaired social communication and repetitive behaviors, and environmental and genetic factors are involved in its onset. The use of the antiepileptic drug valproic acid (VPA) during pregnancy is associated with neural tube defects and developmental disorders in the fetus. In this study, we aimed to identify abnormalities in cortical morphogenesis owing to prenatal VPA exposure and to elucidate the abnormalities in brain function associated with these abnormalities, particularly by comparing multiple and single environments.
View Article and Find Full Text PDFThe relationship between fear of negative evaluation and social anxiety in parents of children with ASD: The chain mediating role of perceived social support and coping styles.
Comput Biol Chem
September 2025
Department of Physical Education, Xidian University, Xi'an 710126, China. Electronic address:
Parents of children with ASD face significantly greater parenting challenges than those raising typically developing children due to prolonged exposure to their children's developmental disorders, emotional distress, and atypical behaviors, underscoring the urgency of addressing their mental health concerns. This study examined the relationship between fear of negative evaluation (FNE) and social anxiety in parents of children with ASD, with a focus on the mediating roles of perceived social support and coping styles. A cross-sectional survey was conducted among 585 parents of children with ASD using validated instruments: the Brief Fear of Negative Evaluation Scale (BFNE), the Social Anxiety Scale, the Perceived Social Support Scale, and the Simple Coping Style Questionnaire.
View Article and Find Full Text PDF