Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Background: Muscle damage has recently been recognized as a complication of type 2 diabetes mellitus (T2DM). Impaired muscle function adversely affects physical activity, quality of life, and mortality risk. Moreover, waist circumference (WC) is associated with visceral fat and insulin resistance. This study investigated the correlation between relative muscle strength and WC in patients with T2DM.
Methods: Patients aged 50 years or older with T2DM were recruited from Taipei Veterans General Hospital. WC was measured at the umbilicus level. Total muscle mass was assessed using bioelectrical impedance analysis. The muscle strength of handgrip, knee extension, ankle dorsiflexion, and ankle plantar flexion were evaluated using a hand-held dynamometer.
Results: A total of 252 patients (mean age 69.4 years; 122 men and 130 women) were enrolled. They were stratified into three groups according to WC (< 85 cm, 85-94 cm, > 94 ;cm). Patients with a larger WC had a higher body mass index and greater muscle mass but had lower relative muscle strength of handgrip, knee extension, ankle dorsiflexion, and ankle plantar flexion. Of note, patients with abdominal obesity (WC ≥ 90 cm in men and WC ≥ 80 cm in women) had significantly lower relative muscle strength of handgrip and lower limb compared to those without in both sexes. Multivariable analyses revealed that WC was significantly and negatively correlated with relative muscle strength after adjusting for other clinical variables.
Conclusion: WC, independent of muscle mass, is a good determinant of relative muscle strength in patients with T2DM. Measuring WC can help identify patients with T2DM at a high risk of low relative muscle strength, thereby broadening the scope of health screening in this population.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/JCMA.0000000000001288 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Effects of different negative pressure cupping interventions on inflammatory response and motor function recovery in delayed onset muscle soreness.
Front Sports Act Living
August 2025
School of Physical Education, Zhejiang Guangsha Vocational and Technical University of Construction, Dongyang, China.
Introduction: This study examined the impacts of different negative pressure cupping therapies (PCT) on pain relief, functional recovery, and inflammatory regulation in delayed onset muscle soreness (DOMS) after high-intensity exercise, with the aim of clarifying the dose-effect relationship.
Methods: In this study, 55 healthy male participants aged 18-25 were selected and divided into 5 groups: the control group (CTR; = 11) and NPCT groups at different levels (-25 kPa, -35 kPa, -45 kPa, and -55 kPa; = 11 in each group). A high-intensity protocol, which included 6 sets of lunges, squats, and squat jumps, was adopted to induce DOMS in the quadriceps femoris.
Predicting injury risk in young female volleyball players through movement and jump assessments.
Front Public Health
September 2025
Gülhane Faculty of Physiotherapy and Rehabilitation, University of Health Sciences, Ankara, Türkiye.
Background: The increasing prevalence of sports injuries among young female volleyball players, driven by biomechanical and hormonal factors, necessitates effective prevention strategies. Screening tools like the Functional Movement Screen (FMS) and Star Excursion Balance Test (SEBT) often show inconsistent predictive validity for injury risk in this population. This study investigates associations between FMS, SEBT, agility, and muscle strength with injury risk in young female volleyball players to refine prediction models and inform targeted interventions.
View Article and Find Full Text PDFBlood flow restriction training: a new approach for preventing and treating sarcopenia in older adults.
Front Physiol
August 2025
Department of Sports Medicine, Wuhan Sports University, Wuhan, China.
With the intensification of population aging, sarcopenia in older adults has become a significant public health issue affecting quality of life. Sarcopenia is a progressive and systemic skeletal muscle disorder characterized by reduced muscle mass, decreased muscle strength, and diminished physical function. Although conventional exercise interventions have shown some efficacy in managing sarcopenia, their effects are limited and often insufficient to effectively halt disease progression.
View Article and Find Full Text PDFLong COVID-19 alters muscle architecture and muscle-tendon force transmission: a one-year longitudinal study.
Front Physiol
August 2025
Laboratory of Muscle and Tendon Plasticity, Graduate Program in Rehabilitation Science, Faculdade de Ciências e Tecnologias em Saúde, Universidade de Brasília, Brasília, Brazil.
Introduction: There are limited studies on the long-term effects of COVID-19 on skeletal muscle morphology and architecture. Therefore, this study aims to address this gap by assessing the effects of prior COVID-19 infection on quadriceps muscle architecture and tendon-aponeurosis complex (TAC) properties over a one-year period, comparing three cohorts: individuals with moderate COVID-19, individuals with severe COVID-19, and a healthy control group.
Methods: Seventy participants were included in the study and allocated to three groups: moderate COVID-19 (n = 22), severe COVID-19 (n = 18), and control (n = 30).
Effect of five non-invasive treatments on body composition, physical function and quality of life in elderly sarcopenia: a network meta-analysis of 22 randomized controlled trials.
Front Physiol
August 2025
College of P.E and Sports, Beijing Normal University, Beijing, China.
Introduction: While exercise interventions are widely used for sarcopenia management, the comparative efficacy of different non-invasive treatments remains unclear. This network meta-analysis evaluated five interventions (aerobic training, resistance training, aerobi-resistance training, whole-body electrical stimulation, and electrical stimulation with protein supplementation) on body composition, physical function and quality of life in elderly sarcopenia patients.
Methods: Six databases, including PubMed, Embase and Web of Science, were systematically searched, and 22 randomized controlled trials with a total of 1062 elderly patients with sarcopenia were finally included.