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With the intensification of population aging, sarcopenia in older adults has become a significant public health issue affecting quality of life. Sarcopenia is a progressive and systemic skeletal muscle disorder characterized by reduced muscle mass, decreased muscle strength, and diminished physical function. Although conventional exercise interventions have shown some efficacy in managing sarcopenia, their effects are limited and often insufficient to effectively halt disease progression. Therefore, exploring more efficient exercise interventions is of great importance. Blood flow restriction training (BFRT), as an emerging exercise intervention, has garnered increasing attention in recent years for its application in sarcopenia among older adults. Studies suggest that, compared to traditional resistance exercise, BFRT demonstrates superior effectiveness in improving muscle strength and mass in older adults, potentially serving as a viable alternative to conventional training methods. However, BFRT also presents certain limitations, including potential risks such as cardiovascular responses and muscle injury. Therefore, careful consideration of appropriate application scenarios and exercise loads is crucial during its implementation. This study reviews the biological mechanisms of BFRT in the intervention of sarcopenia and proposes tailored training protocols and application models for older adults. Furthermore, it thoroughly examines the potential risks and applicability of BFRT, aiming to provide theoretical foundations and practical guidance for clinical application. Additionally, the limitations of current research are analyzed, offering recommendations for future research directions.
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http://dx.doi.org/10.3389/fphys.2025.1616874 | DOI Listing |
J Orthop Res
September 2025
Institute of Orthopaedic Research and Biomechanics, University Medical Center Ulm, Ulm, Germany.
Osteoporotic hip fractures are a considerable cause of pain and disability particularly among the elderly. Osteoporosis causes loss of bone stability, which in turn leads to an increased risk of fractures especially in metaphyseal bone. Moreover, the body's capacity for healing is diminished, resulting in prolonged recovery times following these fractures.
View Article and Find Full Text PDFBMC Psychol
September 2025
Institute of Health and Care Sciences, Sahlgrenska Academy, University of Gothenburg, Box 457, Gothenburg, 405 30, Sweden.
Patients' sense of safety and well-being may be affected in numerous ways while being cared for in hospitals. Often, feelings of alienation arise, as private spaces like the home are inaccessible. One aspect that impacts patients' safety and well-being is the design of the physical care environment.
View Article and Find Full Text PDFGeroscience
September 2025
Department of Emergency and Internal Medicine, Skåne University Hospital, Malmö, Sweden.
To evaluate a simplified version of the Clinical Frailty Scale (SCFS) among older adults presenting to the emergency department (ED) with acute dyspnea. In this retrospective single-center cohort study, we included patients from the Acute Dyspnea Study (ADYS) cohort. Severity of illness was assessed using the Medical Emergency Triage and Treatment System (METTS).
View Article and Find Full Text PDFJ Neural Transm (Vienna)
September 2025
Department of Clinical and Health Psychology, University of Vienna, Liebiggasse 5, Vienna, 1010, Austria.
Tiredness may be associated with increased or decreased sexual experience and behavior while fatigue seems to have a predominantly negative effect, although evidence is scarce. This ecological momentary assessment study is the first to examine associations between tiredness or fatigue and concurrent / subsequent sexual desire or sexual arousal and previous / subsequent sexual activity in daily life, including event-based measurements and considering gender differences. Healthy heterosexual individuals (n = 63), aged between 19 and 32 years and in a relationship, indicated their tiredness, general fatigue, physical fatigue, sexual desire, and sexual arousal on an iPod seven times daily over 14 days, and any event-based occurrences of sexual activity.
View Article and Find Full Text PDFJ Gen Intern Med
September 2025
UCSF Benioff Homelessness and Housing Initiative, University of California, San Francisco, CA, USA.
Background: Older homeless-experienced adults are at higher risk of loneliness than general older adults. Loneliness is associated with multiple adverse health and mental health outcomes. Less is known about factors contributing to loneliness among older adults who experience homelessness.
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