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Background: The aim of this study was to assess the prevalence and clustering of cardiovascular disease (CVD) risk factors among ethnic minorities in plateau areas and their association with sociodemographic characteristics.
Methods: From September 2023 to January 2024, data were collected among ethnic minorities in plateau areas of Yunnan Province through face-to-face interviews. Ordered logistic regression and restricted cubic splines were used to assess the association between sociodemographic characteristics and the risk of clustering of risk factors.
Results: A total of 2457 participants with a median age of 56.00 years were investigated. Insufficient vegetable and fruit intake (42.21%) was the most prevalent behavioral risk factor, followed by current smoking (26.62%). Hypertension (44.24%) was the most prevalent metabolic risk factor, followed by overweight/obesity (39.32%). Among participants, 44.36% had one behavioral risk factor, 21.69% had two, and 4.84% had three or more. The prevalence of participants having 1, 2, 3 or ≥ 4 metabolic risk factors was 29.55%, 21.86%, 15.83% and 5.54%, respectively. The clustering of behavioral risk factors was more prominent among participants aged 65-75, males, Tibetans, illiterates, and rural residents, while the risk of metabolic risk factor clustering was greater in older individuals, those with a high school education or higher, urban residents, and those with higher household incomes.
Conclusions: CVD risk factors are highly prevalent and clustered among ethnic minorities in plateau areas of Yunnan Province, displaying heterogeneity across sociodemographic characteristics. Interventions targeting these risk factors may reduce the CVD burden of ethnic minorities in the plateau areas.
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http://dx.doi.org/10.1186/s12889-025-23864-0 | DOI Listing |
Pediatr Blood Cancer
September 2025
Acute Myeloid Leukemia Sub-Committee, Association of Childhood Leukemia Study (JACLS), Japan.
Background: Relapsed or refractory cases of pediatric acute myeloid leukemia (AML) have poor outcomes despite advancements in chemotherapy and hematopoietic stem cell transplantation (HSCT). While a second HSCT is often a salvage option, its outcomes vary widely, and prognostic factors remain unclear.
Objectives: This study aimed to evaluate outcomes and identify prognostic factors in pediatric patients with AML who underwent multiple HSCTs.
Alzheimers Dement
September 2025
School of Pharmacy, Faculty of Medicine and Health, The University of Sydney, Camperdown, Sydney, New South Wales, Australia.
Introduction: Risperidone is approved for behaviors and psychological symptoms of dementia (BPSD), despite modest efficacy and known risks. Identifying responsive symptoms, treatment modifiers, and predictors is crucial for personalized treatment.
Method: A one-stage individual participant data meta-analysis of six randomized controlled trials (risperidone: n = 1009; placebo: N = 712) was conducted.
Semin Dial
September 2025
Department of Nephrology, Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital, New Delhi, India.
Background: In hyponatremic patients, concurrent dialysate flow during hemodialysis may be an ideal option to mitigate complications such as osmotic demyelination syndrome (ODS).
Methods: Present randomized controlled trial enrolled dialysis-requiring chronic kidney disease (CKD) and acute kidney injury (AKI) patients with serum sodium levels < 125 mEq/L during January 2020 over 16 months. Hemodynamically unstable patients, as well as those with a history of seizures and neurological conditions, were excluded.
J Assist Reprod Genet
September 2025
Morsani College of Medicine, Department of Obstetrics and Gynecology, University of South Florida, 2 Tampa General Circle, STC 6th Floor, Tampa, FL, 33606, USA.
Purpose: Prior studies in fresh embryo transfer IVF cycles have associated elevated serum progesterone level on day of ovulatory trigger, particularly if ≥ 1.5 ng/ml, with decreased pregnancy rates. A similar association has been found in intrauterine insemination (IUI) cycles using gonadotropins for ovulation induction.
View Article and Find Full Text PDFAnn Hematol
September 2025
Centre on Aging and Mobility, University of Zurich, Zurich, Switzerland.
While frailty and anemia are prevalent conditions in aging linked to adverse outcomes, their relationship remains understudied in generally healthy older adults. We conducted a post-hoc observational study among all participants of DO-HEALTH, the largest European clinical trial designed to support healthy aging. Our analysis examined whether baseline hemoglobin levels and anemia are associated with being at least pre-frail at baseline and any yearly follow-up time point over three years.
View Article and Find Full Text PDF