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Pre-trained language models (PLMs) have attracted enormous attention over the past few years with their unparalleled performances. Meanwhile, the soaring cost to train PLMs as well as their amazing generalizability have jointly contributed to few-shot fine-tuning and prompting as the most popular training paradigms for natural language processing (NLP) models. Nevertheless, existing studies have shown that these NLP models can be backdoored such that model behavior is manipulated when trigger tokens are presented. In this paper, we propose PromptFix, a novel backdoor mitigation strategy for NLP models via adversarial prompt-tuning in few-shot settings. Unlike existing NLP backdoor removal methods, which rely on accurate trigger inversion and subsequent model fine-tuning, PromptFix keeps the model parameters intact and only utilizes two extra sets of soft tokens which approximate the trigger and counteract it respectively. The use of soft tokens and adversarial optimization eliminates the need to enumerate possible backdoor configurations and enables an adaptive balance between trigger finding and preservation of performance. Experiments with various backdoor attacks validate the effectiveness of the proposed method and the performances when domain shift is present further shows PromptFix's applicability to models pre-trained on unknown data source which is the common case in prompt tuning scenarios.
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http://dx.doi.org/10.18653/v1/2024.naacl-long.177 | DOI Listing |
Dtsch Med Wochenschr
September 2025
Klinik für Kardiologie, Angiologie und Pneumologie, Institut für Cardiomyopathien Heidelberg, Universitätsklinikum Heidelberg, Heidelberg, Deutschland.
Rapid advancements in Artificial Intelligence (AI) have significantly impacted multiple sectors of our society, including healthcare. While conventional AI has been instrumental in solving mainly image recognition tasks and thereby adding in well-defined situations such as supporting diagnostic imaging, the emergence of generative AI is impacting on one of the main professional competences: doctor-patient interaction.A convergence of natural language processing (NLP) and generative AI is exemplified by intelligent chatbots like ChatGPT.
View Article and Find Full Text PDFInt J Med Inform
September 2025
Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. Electronic address:
Background: Identifying patient-specific barriers to statin therapy, such as intolerance or deferral, from clinical notes is a major challenge for improving cardiovascular care. Automating this process could enable targeted interventions and improve clinical decision support (CDS).
Objective: To develop and evaluate a novel hybrid artificial intelligence (AI) framework for accurately and efficiently extracting information on statin therapy barriers from large volumes of clinical notes.
Brain Behav
September 2025
Department of Electrical and Computer Engineering, University of Tabriz, Tabriz, Iran.
Purpose: Depression among college students is a growing concern that negatively affects academic performance, emotional well-being, and career planning. Existing diagnostic methods are often slow, subjective, and inaccessible, underscoring the need for automated systems that can detect depressive symptoms through digital behavior, particularly on social media platforms.
Method: This study proposes a novel natural language processing (NLP) framework that combines a RoBERTa-based Transformer with gated recurrent unit (GRU) layers and multimodal embeddings.
Crit Care Res Pract
August 2025
Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Sepsis remains one of the leading causes of morbidity and mortality worldwide, particularly among critically ill patients in intensive care units (ICUs). Traditional diagnostic approaches, such as the Sequential Organ Failure Assessment (SOFA) and systemic inflammatory response syndrome (SIRS) criteria, often detect sepsis after significant organ dysfunction has occurred, limiting the potential for early intervention. In this study, we reviewed how artificial intelligence (AI)-driven methodologies, including machine learning (ML), deep learning (DL), and natural language processing (NLP), can aid physicians.
View Article and Find Full Text PDFActa Psychol (Amst)
September 2025
Management Department, Faculty of Economics, Administrative, and Social Sciences, Alanya University, 07400, Alanya, Antalya, Turkiye. Electronic address:
Online communities such as Reddit offer neurodivergent individuals a unique space to express emotions, seek psychosocial support, and negotiate identity outside conventional social constraints. Understanding how these communities articulate and structure emotional discourse is essential for inclusive technology design. This study employed a hybrid natural language processing (NLP) framework that integrates lexicon-based sentiment analysis (VADER) with transformer-based topic modeling (BERTopic).
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