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Objectives: In this protocol, we describe a planned intervention to adapt the Mother Mentor (MoMent) peer support program for women living with HIV (WLWH). WLWH face a six-fold higher risk of cervical cancer, yet screening and treatment rates remain low in Nigeria.
Methods: Using an implementation science approach, we will engage key stakeholders-including ministries of health, NACA, professional bodies, WLWH, Mentor Mothers, healthcare providers, and development partners (e.g., WHO, US CDC, USAID)-through deliberative democracy to adapt and expand MoMent for home-based HPV screening and follow-up treatment. We will pilot the adapted MoMent HIV+HCC program with 1,500 women in 15 health facilities across Nigeria's five geopolitical zones. The RE-AIM framework will guide evaluation of reach, adoption, fidelity, effectiveness, and sustainability.
Results: This study is designed to contribute to WHO's global strategy to eliminate cervical cancer by improving access to home-based screening and care in low-resource settings.
Conclusion: Findings will inform national HPV prevention efforts and may drive broader integration into Nigeria's cervical cancer program.
Clinical Trial Registration: Clinicaltrials.gov, identifier NCT06751030.
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http://dx.doi.org/10.3389/ijph.2025.1608716 | DOI Listing |
Nutr Clin Pract
September 2025
Department of Clinical Nutrition, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Objective: The cachexia index (CXI) demonstrates potential as both a diagnostic tool for cachexia and a prognostic tool for survival in cancer. However, CXI's predictive value has not been verified in cervical cancer. The purpose of this study is to investigate the prognostic value of the CXI in patients with cervical cancer treated with radiotherapy.
View Article and Find Full Text PDFBr J Cancer
September 2025
Istituto Oncologico Veneto IOV-IRCCS, Padova, Italy.
The European Council recommends adopting risk-based screening when relevant. In triaging HPV-positive women, it can be an effective strategy to reduce overtreatment and referral to colposcopy. HPV genotyping and p16/ki67 expression may allow a better risk stratification than cytology.
View Article and Find Full Text PDFPsychooncology
September 2025
Department of Clinical Nursing, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Background: Sub-Saharan Africa (SSA) bears the highest global burden of cervical cancer. Living with the disease is a complex experience, leading to significant changes across various biopsychosocial dimensions, which in turn affect the quality of life of affected women.
Aims: This review aimed to synthesize available scientific evidence on the life experiences of women diagnosed with cervical cancer in SSA in order to generate valuable insights into the care of the affected population.
J Int Med Res
September 2025
Department of Hepatobiliary Surgery, The Affiliated People's Hospital of Ningbo University, China.
This study explores effective treatment methods for chronic secondary lymphedema after radical cervical cancer surgery combined with pelvic lymphadenectomy. In cases where conservative treatment was ineffective, we investigated whether multiple injections of indocyanine green can effectively improve the outcomes of lymphatic-venous anastomosis under microscopy. Preoperative lymphatic imaging was used to localize functional vessels, guiding distal left lower limb lymphatic reconstruction.
View Article and Find Full Text PDFAnn Behav Med
January 2025
Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville, MD 20850, United States.
Background: Hispanic/Latina women in the United States have high rates of cervical cancer and little is known regarding how sociocultural factors might be related to their cervical cancer prevention behaviors.
Purpose: Two studies examined correlates of human papillomavirus (HPV) vaccine initiation, HPV vaccine completion, ever screening for cervical cancer, and being up to date with screening among screening- and vaccine-eligible Hispanic/Latina women.
Methods: Study 1 examined sociodemographic correlates of these behaviors using data from the Behavioral Risk Factor Surveillance System.