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Background: There is no standard analgesic pathway after percutaneous nephrolithotomy. At our institution, an Enhanced Recovery After Surgery (ERAS) pathway was instated that included a preoperative erector spinae plane (ESP) block to improve pain control and minimize opioid usage in the postoperative setting.
Materials And Methods: At our institution, an ERAS pathway was created for patients undergoing percutaneous nephrolithotomy. This pathway involved a preoperative ESP block and the replacement of opioids with multimodal analgesia. Patient charts were retrospectively reviewed and placed into 2 cohorts: one cohort participated in the ERAS pathway, whereas the other received traditional pain control. The primary outcome evaluated was postoperative morphine equivalents received. Secondary outcomes included nursing pain scores, opioid prescriptions for home, and quality of life. Descriptive statistics were performed by nonparametric Mann-Whitney and tests for continuous and categorical variables, respectively.
Results: Sixty patients were identified in the ERAS cohort versus 70 in the traditional pain control cohort. There was a statistically significant difference in average postoperative morphine equivalents received (17.0 vs. 39.9, < 0.01) and average postoperative nursing pain score (2.4 vs. 3.6, < 0.01). Fifty-three percent (32/60) of patients in the ERAS cohort received an opioid prescription for home compared with 80% (56/70) in the traditional cohort ( < 0.01). There was no significant quality-of-life difference between the groups. No adverse patient events resulted from the block.
Conclusions: An ERAS pathway including a preoperative ESP block and multimodal analgesia decreased morphine equivalents received and nursing pain scores. Future randomized prospective studies with the ERAS protocol can be considered.
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http://dx.doi.org/10.1097/CU9.0000000000000283 | DOI Listing |
Cureus
September 2025
General Surgery, Norfolk and Norwich University Hospital, Norwich, GBR.
Enhanced recovery after surgery (ERAS) protocols are increasingly used in total hip and knee arthroplasty to improve outcomes, reduce complications, and shorten hospital stays. This involves a multidisciplinary, evidence-based approach covering the preoperative to postoperative period. This review explores the current literature on ERAS implementation in elective total hip arthroplasty (THA) and total knee arthroplasty (TKA), focusing on clinical outcomes such as length of stay (LOS), opioid use, complications/readmissions, and other key components such as anesthetic standardization, use of opioid-sparing analgesia agents, early mobilization, and patient satisfaction.
View Article and Find Full Text PDFBone Jt Open
September 2025
School of Medicine, University of Nottingham, Nottingham, UK.
Aims: The number of hip fractures is increasing, with significant mortality and morbidity, particularly among frail and comorbid patients. Enhanced recovery after surgery (ERAS) pathways have proven effective in elective orthopaedics, but this has not been investigated in people with hip fractures. This study aimed to identify current perioperative practice and develop a cohesive ERAS pathway tailored for hip fracture patients, to standardize and optimize care.
View Article and Find Full Text PDFCurr Urol
September 2025
Department of Urology, University of Rochester, Rochester, NY, USA.
Background: There is no standard analgesic pathway after percutaneous nephrolithotomy. At our institution, an Enhanced Recovery After Surgery (ERAS) pathway was instated that included a preoperative erector spinae plane (ESP) block to improve pain control and minimize opioid usage in the postoperative setting.
Materials And Methods: At our institution, an ERAS pathway was created for patients undergoing percutaneous nephrolithotomy.
Acta Neurochir (Wien)
September 2025
UCLA Department of Neurosurgery, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA.
Background And Objectives: Neurosurgical procedures can be associated with significant post-operative pain and diminished ability to ambulate or transfer, frequently requiring evaluation by physical / occupational therapy (PT/OT) to ensure appropriate discharge disposition. Owing to high demand for PT/OT services across surgical subspecialities, PT/OT evaluation often bottlenecks disposition. Through our established cranial Enhanced Recovery After Surgery (ERAS) pathway, Neurosurgery Enhanced Recovery Value and Safety (NERVS), our institution employs a nurse-driven mobilization component during post-operative recovery.
View Article and Find Full Text PDFFront Med (Lausanne)
August 2025
Department of Nephrology, Tianyou Hospital, Wuhan University of Science and Technology, Wuhan, China.
Diabetic kidney disease (DKD) has emerged as the leading cause of chronic kidney disease (CKD) worldwide, surpassing primary glomerular disorders in prevalence. Despite recent therapeutic advances, current treatment strategies primarily alleviate symptoms rather than address the underlying pathogenic mechanisms, highlighting an urgent need for targeted, mechanism-based interventions. The pathogenesis of DKD involves a complex interplay of metabolic, hemodynamic, inflammatory, oxidative, and fibrotic pathways.
View Article and Find Full Text PDF