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To evaluate and compare pregnancy outcomes following successful fluoroscopy-guided tubal recanalization (FGTR), focusing on spontaneous conception versus intrauterine insemination (IUI). This retrospective cohort study included 139 women aged 21-40 years who underwent FGTR for tubal occlusion between January 2021 and May 2024. After exclusions, 80 women attempted natural conception, and 59 underwent IUI with ovarian stimulation. Groups were compared in terms of clinical pregnancy rates, time to conception, and post-procedure tubal patency. Clinical pregnancy rates were similar between spontaneous conception (51.2%) and IUI (57.6%) groups (p = 0.976). Mean time to conception did not differ significantly (6.4 ± 2.8 vs. 5.9 ± 2 months, p = 0.360). No pregnancies occurred in women with bilateral distal obstruction, whereas proximal occlusions (unilateral or bilateral) were associated with higher pregnancy rates. Six-month follow up HSG demonstrated that bilateral tubal patency correlated with greater conception likelihood. In women with tubal factor infertility who achieve patency after FGTR, spontaneous conception and IUI yield comparable pregnancy outcomes and similar time to conception. Expectant management may be a cost-effective first-line approach, reserving IUI or IVF for cases without conception within a reasonable timeframe. The site of tubal obstruction and patency status should guide individualized post-FGTR fertility planning.
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http://dx.doi.org/10.1038/s41598-025-17762-z | DOI Listing |
Eur J Prev Cardiol
September 2025
Department of Cardiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Background And Aims: Data on cardiovascular outcomes and aortic growth in pregnant women with Turner syndrome is limited. We examine the cardiovascular and pregnancy outcomes in these women and analyze aortic growth throughout pregnancy.
Methods: The ROPAC III is a global, prospective, observational registry that enrolled pregnancies of women pre-pregnancy known with Turner syndrome from 2018 to 2023.
J Plant Physiol
September 2025
Department of Plant Physiology, University of Granada, Granada, Spain. Electronic address:
Legumes form symbioses with nitrogen-fixing bacteria, well studied metabolically but less so in terms of respiration. Symbiotic nitrogen fixation demands high respiratory ATP and carbon skeletons, linking nitrogen assimilation and both NADH- and ATP-dependent process to mitochondrial respiration. The plant mitochondrial electron transport chain contains two terminal oxidases that differentially fractionate against O, providing estimations in vivo of the energy efficiency of respiration.
View Article and Find Full Text PDFRheumatol Int
September 2025
Division of Perinatology, Department of Obstetrics, Zeynep Kamil Women and Children's Diseases Training and Research Hospital, Istanbul, Turkey.
Familial Mediterranean Fever (FMF) is frequently diagnosed during reproductive ages, but its impact on pregnancy remains unclear. We aimed to evaluate maternal and neonatal outcomes in FMF pregnancies by comparing before and after diagnosis periods as well as with healthy controls, and to identify predictors of adverse outcomes. This retrospective, cross-sectional study included 215 pregnancies (129 before and 86 after FMF diagnosis) from 81 women with FMF and 94 pregnancies from 42 healthy controls.
View Article and Find Full Text PDFbioRxiv
August 2025
Department of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth, Hanover, NH, USA.
Mammalian female meiosis is uniquely regulated to produce a developmentally competent egg capable of supporting embryogenesis. During meiosis I, homologous chromosomes segregate, with half extruded into the first polar body. The egg then arrests at metaphase II and only resumes meiosis and extrudes the second polar body following fertilization.
View Article and Find Full Text PDFJ Assist Reprod Genet
September 2025
Department of Reproductive Medicine, General Hospital of Northern Theater Command, No. 83, Wenhua Road, Shenhe District, Shenyang, 110016, China.
Objective: The association between anti-Müllerian hormone (AMH) levels and embryonic aneuploidy rates was investigated by analyzing clinical and embryo laboratory data from patients with preimplantation genetic testing for aneuploidy (PGT-A). However, the nonlinear relationship and threshold effect of AMH on aneuploidy risk remain poorly understood.
Methods: This retrospective study analyzed the clinical data of 819 PGT-A cycles performed between January 2018 and August 2024 at the General Hospital of Northern Theater Command.