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http://dx.doi.org/10.1055/a-2685-9769 | DOI Listing |
J Neuroimmunol
August 2025
Department of Neurology, Tianjin Medical University General Hospital, Tianjin 300052, China; Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin 300052, China. Electronic address:
We present a clinically instructive case of a 50-year-old woman with acetylcholine receptor (AChR) antibody-positive generalized myasthenia gravis (MG) who subsequently developed glutamic acid decarboxylase 65 (GAD65) antibody-associated neurological disorders alongside a type B2 thymoma. This rare coexistence highlights the profound immune dysregulation induced by thymomas, wherein loss of self-tolerance emergence multiple concurrent autoimmune phenomena. The patient's favorable response to multimodal immunotherapy-including efgartigimod, high-dose corticosteroids, and rituximab-underscores the therapeutic imperative for early, targeted immunomodulation in such complex neuroimmunological syndromes.
View Article and Find Full Text PDFJACC Case Rep
September 2025
Cardiovascular Imaging Department, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico.
Coarctation of the aorta and aortic thrombus coexistence is extremely rare. This case series presents 2 adult patients with diverse presentations of coarctation of the aorta complicated by aortic thrombus characterized by cardiac computed tomography angiography.
View Article and Find Full Text PDFJACC Case Rep
September 2025
Meyer University Hospital, Florence, Italy.
Background: Single coronary artery is a rare congenital anomaly. Its coexistence with coronary artery fistula is exceedingly uncommon.
Case Summary: A 61-year-old woman with no cardiovascular risk factors underwent her first cardiological evaluation after incidental detection of atrial fibrillation.
Occup Med (Lond)
September 2025
Department of Internal Diseases, Occupational Diseases Unit, Ministry of Health Ankara Etlik City Hospital, Ankara, Turkey.
Caplan syndrome, a rare condition characterized by the coexistence of pneumoconiosis and rheumatoid arthritis in individuals exposed to inorganic dust, remains a relevant diagnostic consideration in the 21st century. We present a case of a 41-year-old former coal miner who developed multiple cavitary pulmonary nodules years after leaving the mining sector, initially mimicking pulmonary malignancy. Extensive diagnostic work-up, including positron emission tomography-computed tomography, bronchoscopy and lung biopsy, eventually led to the diagnosis of Caplan syndrome, with seropositive rheumatoid arthritis emerging 8 years after exposure cessation.
View Article and Find Full Text PDFIntractable Rare Dis Res
August 2025
Department of Radiology & Diagnostic Imaging, University of Alberta, Edmonton, Alberta, Canada.
Renal oncocytomas are benign renal tumours characterized by a central stellate scar that are indistinguishable on CT/MR imaging from malignant chromophobe renal cell carcinomas (ChrRCCs). Renal oncocytomas and ChrRCCs can be separate entities but can also co-exist on a spectrum in hybrid oncocytic/ chromophobe tumours. In the past, invasive biopsy and pathologic diagnosis has been relied on to differentiate these lesion and direct management.
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