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http://dx.doi.org/10.1093/toxsci/kfaf121 | DOI Listing |
Chem Asian J
September 2025
School of Medical Information Engineering, Shenyang Medical College, Shenyang, Liaoning, 110043, P. R. China.
The rational design of electrode materials with outstanding energy and power density for supercapacitors (SCc) and high-performance electrocatalysts in alkaline media plays an indispensable role in the application of energy storage and overall water splitting. In this paper, we prepared NiCoFe layered ternary hydroxides (LTH) using a hydrothermal synthesis method. The sample with a Ni/Co/Fe ratio of 1:2:0.
View Article and Find Full Text PDFPlant Sci
September 2025
Guangdong Provincial Key Laboratory of Postharvest Science of Fruits and Vegetables/Key Laboratory of Biology and Genetic Improvement of Horticultural Crops (South China), Ministry of Agriculture and Rural Affairs, College of Horticulture, South China Agricultural University, Guangzhou, 510642, Chin
Chlorophyll is vital for plants, giving them their green color and playing indispensable crucial role in photosynthesis. Chlorophyll-deficient mutants serve as classic models for studying plant pigment metabolism and typically exhibit chlorotic or albino phenotypes, resulting in major impacts on photosynthetic efficiency and growth development of plants. Understanding the mechanisms behind chlorophyll deficiency not only advances basic plant biology but also supports crop breeding strategies aimed at improving yield, stress tolerance, and adaption.
View Article and Find Full Text PDFBiomed Eng Lett
September 2025
Department of Radiology, Guizhou International Science and Technology Cooperation Base of Precision Imaging for Diagnosis and Treatment, Guizhou Provincial People's Hospital, Guiyang, Guizhou China.
The generated lung nodule data plays an indispensable role in the development of intelligent assisted diagnosis of lung cancer. Existing generative models, primarily based on Generative Adversarial Networks (GANs) and Denoising Diffusion Probabilistic Models (DDPM), have demonstrated effectiveness but also come with certain limitations: GANs often produce artifacts and unnatural boundaries, and due to dataset limitations, they struggle with irregular nodules. While DDPMs are capable of generating a diverse range of nodules, their inherent randomness and lack of control limit their applicability in tasks such as segmentation.
View Article and Find Full Text PDFACS Chem Neurosci
September 2025
School of Life Science and Technology, Key Laboratory of Developmental Genes and Human Disease, Southeast University, Nanjing 210096, China.
Glial cells play an indispensable role in the nervous system, providing structural support to neurons and regulating their function and development. Glia support neural network formation and plasticity in axon guidance, synaptic pruning, and neurogenesis. Of note, studies have shown that glial cell dysfunction is closely related to the occurrence of neurological diseases.
View Article and Find Full Text PDFJ Genet Genomics
September 2025
Institute of Pediatrics, Children's Hospital of Fudan University, and Shanghai Key Laboratory of Medical Epigenetics, International Co-laboratory of Medical Epigenetics and Metabolism, Ministry of Science and Technology, Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China; Sh
Chromodomain helicase DNA binding protein 7 (CHD7), an ATP-dependent chromatin remodeler, plays versatile roles in neurodevelopment. However, the functional significance of its ATPase/nucleosome remodeling activity remains incompletely understood. Here, we generate genetically engineered mouse embryonic stem cell lines harboring either an inducible Chd7 knockout or an ATPase-deficient missense variant identified in individuals with CHD7-related disorders.
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