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Malnutrition is a common problem in aging populations. Studies show that up to one-third of hospital patients are affected. Malnutrition is linked to various health concerns, including poor muscle function, decreased bone density, immunological dysfunction, cognitive decline, anemia, prolonged hospital admissions, and higher morbidity and mortality. This study compares the diagnostic performance of the Nutritional Risk Screening 2002 (NRS-2002) score, Subjective Global Assessment (SGA) score, and Nutrition Risk in the Critically Ill (modified Nutric score [mNutric]) score with the gold standard Global Leadership Initiative on Malnutrition (GLIM) criteria in diagnosing malnutrition. The current study was conducted over the period of two months at S. L. Raheja Hospital and included 100 patients over the age of 18. Within the first 24 h after admission, malnutrition screening was performed using NRS-2002, SGA, and mNutric scores, with GLIM criteria as the reference. The GLIM criteria identified 41% of patients as malnourished, but SGA and NRS-2002 revealed 60% and 72%, respectively, and mNutric as 40%. Kappa coefficients demonstrated good agreement between GLIM and mNutric (k = 0.915), moderate agreement with NRS-2002 (k = 0.761), and reasonable agreement with SGA (k = 0.632). Sensitivity and specificity analyses revealed that GLIM has superior diagnostic accuracy. These findings support GLIM criteria as a global standard for malnutrition diagnosis, enhancing clinical outcomes through targeted nutritional interventions. The GLIM criteria demonstrated better agreement with the mNutric score compared to the other two tools. However, incorporating all available screening tools in clinical practice will enhance the early detection of malnutrition.
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http://dx.doi.org/10.1177/02601060251332990 | DOI Listing |
Ther Adv Chronic Dis
September 2025
Department of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Anshan Road 154, Heping District, Tianjin 300052, China.
Background: Liver cirrhosis, characterized by chronic inflammation, is frequently complicated by malnutrition. Nutritional indices, such as the prognostic nutritional index (PNI) and the skeletal muscle index (SMI), calculated as the muscle area quantified via CT scans at the third lumbar vertebra level divided by the square of the patient's height in meters (cm/m), are associated with outcomes in inflammatory diseases.
Objectives: We aimed to evaluate the diagnostic efficacy of the PNI both independently and in combination with the SMI for identifying malnutrition in cirrhosis and to explore their prognostic implications.
Clin Nutr ESPEN
September 2025
Duke University, Department of Surgery, Division of Trauma, Acute, and Critical Care Surgery, Durham, NC, USA. Electronic address:
Background: Up to 70% of lung cancer may be malnourished. This study aims to examine the effects of malnutrition on outcomes in lung cancer patients undergoing resection using modified GLIM criteria.
Methods: The study utilized the mGLIM criteria to identify malnourished patients.
Nutr Clin Pract
September 2025
Nutrition Department, Faculty of Medicine, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.
Background: Early diagnosis of malnutrition is essential for rapid decision-making regarding nutrition care to improve patient outcomes. We aimed to evaluate the prevalence of malnutrition using the Global Leadership Initiative on Malnutrition (GLIM) criteria and to assess the association of GLIM with 1-year mortality and length of hospital stay (LOS) in patients admitted to an emergency department (ED).
Methods: Prospective cohort study conducted in the ED of a university hospital.
Clin Nutr
August 2025
Critical Care Medicine, Yokohama City University Hospital, Kanagawa, Japan.
Background: The Global Leadership Initiative on Malnutrition (GLIM) lacks endorsed criteria for a muscle mass assessment. Since a muscle mass assessment using trunk computed tomography (CT) cannot be performed on all patients, a temporal muscle evaluation may serve as an useful alternative. In the present study, we hypothesized that complementing a total skeletal muscle mass assessment with a temporal muscle evaluation may provide a viable strategy for the GLIM assessment in the intensive care unit (ICU).
View Article and Find Full Text PDFInt J Gen Med
August 2025
Nutrition Department, Affiliated Hospital of Chengde Medical University, Chengde, People's Republic of China.
Purpose: This study aimed to evaluate the individual and joint associations of malnutrition and obesity on predicting the severity and prognosis of acute pancreatitis (AP).
Patients And Methods: A retrospective analysis of 240 AP patients was conducted. Malnutrition was diagnosed using Global Leadership Initiative on Malnutrition (GLIM) criteria.