[Research progress on combined transcranial electromagnetic stimulation in clinical application in brain diseases].

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi

State Key Laboratory of Intelligent Power Distribution Equipment and System, School of Electrical Engineering, Hebei University of Technology, Tianjin 300130, P. R. China.

Published: August 2025


Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

In recent years, the ongoing development of transcranial electrical stimulation (TES) and transcranial magnetic stimulation (TMS) has demonstrated significant potential in the treatment and rehabilitation of various brain diseases. In particular, the combined application of TES and TMS has shown considerable clinical value due to their potential synergistic effects. This paper first systematically reviews the mechanisms underlying TES and TMS, highlighting their respective advantages and limitations. Subsequently, the potential mechanisms of transcranial electromagnetic combined stimulation are explored, with a particular focus on three combined stimulation protocols: Repetitive TMS (rTMS) with transcranial direct current stimulation (tDCS), rTMS with transcranial alternating current stimulation (tACS), and theta burst TMS (TBS) with tACS, as well as their clinical applications in brain diseases. Finally, the paper analyzes the key challenges in transcranial electromagnetic combined stimulation research and outlines its future development directions. The aim of this paper is to provide a reference for the optimization and application of transcranial electromagnetic combined stimulation schemes in the treatment and rehabilitation of brain diseases.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12409495PMC
http://dx.doi.org/10.7507/1001-5515.202410055DOI Listing

Publication Analysis

Top Keywords

transcranial electromagnetic
16
combined stimulation
16
brain diseases
12
electromagnetic combined
12
stimulation
9
transcranial
8
treatment rehabilitation
8
rehabilitation brain
8
tes tms
8
rtms transcranial
8

Similar Publications

Advances in brain stimulation have made it possible to target smaller and smaller regions for electromagnetic stimulation, in the hopes of producing increasingly focal neural effects. However, the brain is extensively interconnected, and the neurons comprising those connections may themselves be particularly susceptible to neurostimulation. Here, we test this hypothesis by identifying long-range projections in single-unit recordings from nonhuman primates receiving transcranial alternating current stimulation.

View Article and Find Full Text PDF

[Research progress on combined transcranial electromagnetic stimulation in clinical application in brain diseases].

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi

August 2025

State Key Laboratory of Intelligent Power Distribution Equipment and System, School of Electrical Engineering, Hebei University of Technology, Tianjin 300130, P. R. China.

In recent years, the ongoing development of transcranial electrical stimulation (TES) and transcranial magnetic stimulation (TMS) has demonstrated significant potential in the treatment and rehabilitation of various brain diseases. In particular, the combined application of TES and TMS has shown considerable clinical value due to their potential synergistic effects. This paper first systematically reviews the mechanisms underlying TES and TMS, highlighting their respective advantages and limitations.

View Article and Find Full Text PDF

Numerical simulation of transcranial static magnetic fields for the treatment of global epilepsy in children.

Sci Rep

August 2025

Neurocom, CICA - Centro Interdisciplinar de Química e Bioloxía, Universidade da Coruña (UDC), Campus de Elviña, A Coruña, Spain.

Transcranial static magnetic stimulation has shown the capacity to decrease systematically the cortical excitability in the treatment of epilepsy. Nevertheless, the application of these therapies to non-focal epilepsies is limited. This paper investigates on the numerical evaluation of promising strategies based on the application of static magnetic fields with multiple magnets on children.

View Article and Find Full Text PDF

Significance: Low-level near-infrared light-induced transcranial photobiomodulation (NIR-TPBM) is a promising technology for improving cerebral blood flow and metabolism. However, the effects of NIR-TPBM on the visual pathway's function remain poorly understood.

Aim: The aim was to assess the visual pathway's function changes in response to NIR-TPBM in young, healthy volunteers.

View Article and Find Full Text PDF

Excitability is a neuronal property quantified as the magnitude of neural response to stimuli. It plays a crucial role in information processing and is disrupted in various neuropsychiatric conditions. In humans, non-invasive measurements of brain excitability have been mostly limited to the primary motor cortex.

View Article and Find Full Text PDF