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Introduction: This report presents data on cardiac pacing system implants in Spain during 2024.
Methods: The registry is based on data voluntarily submitted by implanting centers to the Heart Rhythm Association of the Spanish Society of Cardiology via the national online platform, CardioDispositivos. Additional data sources included: a) data provided by device manufacturers and distributors, b) the European pacemaker patient card, and c) local databases submitted by implanting centers.
Results: A total of 128 hospitals submitted data to the registry (16 more than in 2023 and 46 more than in 2022). In total, 26 412 units were reported (an 8.5% increase compared with 2023 and 60.8% compared with 2022), vs 47 162 units reported by Eucomed (European Confederation of Medical Suppliers Associations). Among these, 1 715 were cardiac resynchronization pacemakers. Leadless pacemaker use continued to rise (1049 devices), accounting for 2.2% of all pacemakers. The most common indication was atrioventricular block, followed by atrial tachyarrhythmia with slow ventricular response. Devices included in remote monitoring also increased: the most notable growth was observed in high-energy resynchronization devices (87%) and leadless pacemakers (38%). Moderate increases were also noted for conventional cardiac resynchronization pacemakers (59%) and standard pacemakers (39%).
Conclusions: Participation in the pacemaker registry continues to grow, reaching 56% of the number of units reported by manufacturers to Eucomed. Remote monitoring maintains the slow but steady growth trend observed in recent years. Full English text available from: www.revespcardiol.org/en.
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http://dx.doi.org/10.1016/j.rec.2025.07.007 | DOI Listing |
Angew Chem Int Ed Engl
September 2025
College of Chemistry and Materials Science, Northwest University, Xi'an, 710069, P.R. China.
Developing artificial hosts with temperature-driven conformational switching behaviors facilitates our understanding of the temperature-dependent allostery and adaptation mechanisms in natural recognition systems. Herein, we report the design and synthesis of three pairs of water-soluble, enantiomeric binaphthalene-based tetraimidazolium macrocycles (SS/RR-1•4Cl- - SS/RR-3•4Cl-) as artificial hosts for exploring sequence-selective recognition of dinucleotides in aqueous media. Owing to the reversible rotational conformation of axially chiral binaphthyl units, SS-1•4Cl- demonstrates the conformational switching, converting from cis-conformation (SS-1) to trans-conformation (SS-1) by increasing temperature, thereby causing the recognition cavity to transition from a closed to an open state.
View Article and Find Full Text PDFBMC Nurs
September 2025
Nursing Administration Department, Faculty of Nursing, Tanta University, Tanta, Egypt.
Background: Nursing interns frequently encounter role ambiguity due to a mismatch between their expectations of the professional nursing role and the actual responsibilities they face in clinical settings. While clinical rotations during the internship year are intended to enhance clinical confidence and competence, such ambiguity can undermine these goals.
Objective: To examine the relationship between internship clinical rotation and role ambiguity among nursing interns.
Lancet Digit Health
September 2025
Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK; NIHR Biomedical Research Centre, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK; Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Background: New-onset atrial fibrillation, a condition associated with adverse outcomes in the short and long term, is common in patients admitted to intensive care units (ICUs). Identifying patients at high risk could inform trials of preventive interventions and help to target such interventions. We aimed to develop and externally validate a prediction model for new-onset atrial fibrillation in patients admitted to ICUs.
View Article and Find Full Text PDFSci Justice
September 2025
Norwegian Fire and Rescue Academy, Erling Johannessens vei 1, 9441 Fjelldal, Norway.
Digital evidence plays a critical role in solving crimes, making its quality essential. This study examines the implementation of a structured, checklist-based peer review process for technical analysis reports within digital forensic units of the Norwegian Police. It incorporates two data collections: a qualitative study based on interviews following a trial implementation, and a quantitative survey assessing peer review practices one year after the trial.
View Article and Find Full Text PDFRespir Physiol Neurobiol
September 2025
Department of Pediatrics, School of Medicine, Duke University.
Pompe disease is an autosomal recessive neuromuscular disorder characterized by a deficiency of acid α-glucosidase (GAA), an enzyme responsible for lysosomal glycogen degradation in all cells. Respiratory distress is a common symptom among patients with Pompe disease resulting from weakness of primary respiratory neuromuscular units of the diaphragm and genioglossus and the motor neurons which innervate them. The only FDA approved treatment is enzyme replacement therapy (ERT) of recombinant human GAA (rhGAA) which slows the decline of motor function and extends life expectancy.
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