Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.jchf.2025.102620 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Sex-specific alterations in placental mitochondria, oxidative damage and apoptosis in mice of advanced maternal age.
Reproduction
October 2025
Maternal and Fetal Health Research Centre, University of Manchester, Manchester, United Kingdom.
In Brief: Advanced maternal age (AMA) is associated with adverse pregnancy outcomes, particularly those associated with placental dysfunction. This study showed that in a mouse model of AMA, male but not female fetuses had increased placental apoptosis and lipid peroxidation, as well as increased mitochondrial content, suggesting that the placentas of male fetuses in AMA mothers adapt to be able to deliver sufficient energy to the fetus.
Abstract: Although advanced maternal age (AMA) increases the risk of fetal growth restriction (FGR) and stillbirth, the mechanisms leading to the placental dysfunction observed in AMA are unknown.
Gene expression changes in ducklings exposed in ovo to emerging and legacy per-/poly-fluoroalkyl substances.
Environ Toxicol Chem
September 2025
Department of Biology, Norwegian University of Science and Technology (NTNU), Trondheim, 7491Norway.
This study investigated the effects of two emerging PFAS compounds, perfluorododecane sulfonic acid (PFDoDS) and perfluoro-4-ethylcyclohexane sulfonic acid (PFECHS), alongside legacy perfluorooctanesulfonic acid (PFOS), on gene expression in the liver, heart, and bursa of Fabricius from mallard ducklings (Anas platyrhynchos) exposed in ovo, simulating maternal transfer to the egg. These PFAS compounds were selected based on their detection in a declining sea duck species and concerns over their endocrine disruption potential. Farmed mallard eggs were injected with 80 ng/g of PFDoDS, PFECHS, or PFOS, reflecting concentrations at the upper end of those reported in wild bird eggs.
View Article and Find Full Text PDFSex-Specific Transfer Outcomes in Patients With Non-Acute Myocardial Infarction-Related Cardiogenic Shock.
JACC Heart Fail
August 2025
The Mass General Brigham Heart and Vascular Institute, Massachusetts General Hospital, Boston, Massachusetts, USA. Electronic address:
Examining the Performance of Polygenic Risk Scores for Alzheimer Disease Within and Across Populations Using -Fold Cross-Validation.
Neurol Genet
December 2024
From the Department of Population and Quantitative Health Sciences (M.D.O., Y.E.S., A.L., K.M., N.R.W., J.B., W.S.B., J.L.H.); Cleveland Institute for Computational Biology (M.D.O., Y.E.S., A.L., W.S.B., J.L.H.), Case Western Reserve University, OH; Department of Medicine (Biomedical Genetics) (L.A.
Background And Objectives: Alzheimer disease (AD) has a complex etiology with a strong genetic component. Despite mounting evidence that genetic risk effect sizes vary by population, most research on the genetics of AD has examined only data sets of individuals with European ancestry. In this study, we investigate the variable performance and transferability of polygenic risk scores (PRSs) by deriving a PRS from analyses of AD for various race and ethnic categories and applying this across groups using a -fold cross-validation approach.
View Article and Find Full Text PDFSpecies- and sex-specific bioaccumulation, tissue-specific distribution, and maternal transfer of per- and polyfluoroalkyl substances in tiger frogs (Hoplobatrachus chinensis) and forest frogs (Rana chensinensis).
Environ Res
August 2025
State Key Laboratory of Advance Environmental Technology, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou, 510640, China; Guangdong-Hong Kong-Macao Joint Laboratory for Environmental Pollution and Control, Guangzhou, 510640, China.
Amphibians are sensitive biomonitors of environmental pollutants. However, existing research on per- and polyfluoroalkyl substances (PFASs) between different species of amphibians is limited. In the present study, water, soil, tiger frog (Hoplobatrachus chinensis) and forest frog (Rana chensinensis) samples were collected from Qingyuan County, South China.
View Article and Find Full Text PDF