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The aim of this study is to present a compound core manufacturing defect identified in a nickel-titanium (NiTi) instrument via fractographic analysis during additional retrospective analysis after dynamic cyclic fatigue resistance testing. This study raises awareness of core manufacturing defects and fosters the development of high-quality NiTi instruments without defects for clinical application. A scanning electron microscope with an acceleration voltage of 5 kV was used for fractographic analysis after cyclic fatigue testing. The fractographic analysis identified a compound core manufacturing defect, involving unmelted powder, and two interconnected failures. To the best of our knowledge, this is the first study to identify such compound core manufacturing defect in a NiTi instrument during fractographic analysis via scanning electron microscopy. The study underscores the need for detection and rectification of manufacturing defects, with methods such as X-ray computed tomography and hot isostatic pressing. The presence of core manufacturing defects in the NiTi instruments elevates the likelihood of premature clinical fracture, which may add to their inherent susceptibility to fracture in root canals due to cyclic fatigue and/or torsional stress.
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http://dx.doi.org/10.1111/eos.70037 | DOI Listing |
Med Phys
September 2025
Medical Physics Unit, Department of Oncology, Faculty of Medicine, McGill University, Montréal, Québec, Canada.
Background: Se ( 120 days, 215 keV) offers advantages over Ir ( 74 days, 360 keV) as a high dose rate brachytherapy source due to its lower gamma energy and longer half-life. Despite its widespread use in industrial gamma radiography, a Se brachytherapy source has yet to be manufactured.
Purpose: A novel Se-based source design with a vanadium diselenide core, titled the SeCure source, was proposed.
Angew Chem Int Ed Engl
September 2025
Department of Chemistry, Inorganic Chemistry Laboratory, University of Oxford, South Parks Road, Oxford, OX1 3QR, UK.
Topochemical reduction of the n = 2 Ruddlesden-Popper oxide, LaSrCoRuO, yields LaSrCoRuO, a phase containing (Co/Ru)O squares which share corners to form 1D infinite double-chains. In contrast, fluorination of LaSrCoRuO yields the oxyfluoride LaSrCoRuOF, which can then be reduced to form LaSrCoRuOF. This reduced oxyfluoride is almost isoelectronic with LaSrCoRuO, but LaSrCoRuOF has a crystal structure in which the (Co/Ru)O squares are connected into 2D infinite sheets.
View Article and Find Full Text PDFLight Sci Appl
September 2025
State Key Laboratory of Flexible Electronics, Institute of Advanced Materials (IAM), Nanjing University of Posts & Telecommunications (NUPT), Nanjing, 210023, China.
As the demand for edge platforms in artificial intelligence increases, including mobile devices and security applications, the surge in data influx into edge devices often triggers interference and suboptimal decision-making. There is a pressing need for solutions emphasizing low power consumption and cost-effectiveness. In-sensor computing systems employing memristors face challenges in optimizing energy efficiency and streamlining manufacturing due to the necessity for multiple physical processing components.
View Article and Find Full Text PDFClin Rheumatol
September 2025
Department of Dermatology, the First Affiliated Hospital, Army Medical University, No. 29 Gaotanyan Street, Shapingba District, Chongqing, China.
Background: Plasmacytoid dendritic cells (pDCs) are a specialized subset of dendritic cells known for their ability to produce type I interferon (IFN I), contributing to antiviral defense and the pathogenesis of autoimmune diseases like systemic lupus erythematosus (SLE). In SLE patients, pDCs are excessively activated, leading to overproduction of IFN-α, which plays a critical role in disease progression. However, no bibliometric analysis has been conducted on the relationship between pDCs and SLE.
View Article and Find Full Text PDFPhytomedicine
August 2025
College of Food Science and Technology, Yunnan Agricultural University, Kunming 650201, China; Yunnan Provincial Key Laboratory of Precision Nutrition and Personalized Food Manufacturing, Yunnan Agricultural University, Kunming 650201, China; Yunnan Provincial Engineering Research Center for Edible
Background: Walnut septum, a Juglans regia L. by-product with culinary-medicinal value, is a rich source of bioactive polyphenols. The chemical complexity and anti-colitis activities of these polyphenols remain uncharacterized.
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