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The long-term goal of establishing a sustained human presence on Mars requires the capacity to produce essential consumables on-site. To this end, we develop strategies for processing inorganic oxidic powders and biomass into highly particle-filled composites using direct ink writing (DIW) 3D printing. Our approach relies on a simulant of a Martian regolith unit rich in hydrated clay minerals and food-grade spirulina, used as proxies for local regolith and cyanobacterial biomass, respectively. The composites are further reinforced through crosslinking with the plant-based molecule genipin. Detailed rheological analysis was performed for the 3D printing feedstocks, while the printed composites were characterized using thermal gravimetric analysis (TGA), surface area porosity analysis (BET), microscopy and mechanical tests. Dissolution tests demonstrated that genipin effectively crosslinks the cyanobacterial biomass. The outcome is a highly porous, lightweight material with adaptable, complex morphology, which has significant potential for use in the resource-constrained environments of long-duration Mars missions.
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http://dx.doi.org/10.1038/s41526-025-00521-9 | DOI Listing |
Arch Microbiol
September 2025
Department of Botany, Central Instrumentation Facility, Nehru Gram Bharati Deemed to University, Prayagraj, 221505, India.
This review study examines an innovative biotechnological strategy aimed at creating a specialized cyanobacterial ecosystem designed to produce high-quality biomass abundant in compounds that provide protection against solar radiation, specifically scytonemin and mycosporine-like amino acids (MAAs). The remarkable ability of cyanobacteria to produce biomass that is both sustainable and environmentally friendly has attracted considerable attention in recent years, largely due to its wide-ranging applications in various industries. However, a significant challenge remains: the concentrations of these beneficial metabolites within cyanobacteria are typically very low, rendering industrial-scale production economically unviable.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
September 2025
Instituto de Biomedicina y Biotecnología de Cantabria, Universidad de Cantabria-Consejo Superior de Investigaciones Científicas, Santander, Cantabria 39011, Spain.
Circadian clocks allow organisms to anticipate daily fluctuations in light and temperature, but how this anticipatory role promotes adaptation to different environments remains poorly understood. Here, we subjected the cyanobacterium PCC 7942 to a long-term evolution experiment under high light, high temperature, and elevated CO levels. After 1,200 generations, we obtained a strain exhibiting a 600% increase in growth rate.
View Article and Find Full Text PDFFish Physiol Biochem
September 2025
LEGENE-Research Group in Genetic Engineering and Biotechnology, Laboratory of Molecular Biology, Institute of Biological Sciences, Federal University of Rio Grande (FURG), Av. Itália, Km 8, Rio Grande, RS, CEP 96203-900, Brazil.
The application of cyanobacteria as sustainable feed additives in aquaculture has gained increasing attention due to their nutritional and functional properties. In previous studies, we demonstrated that dietary supplementation with Synechococcus elongatus PCC 7942 improved hepatic homeostasis and modulated the intestinal microbiota of zebrafish (Danio rerio), without adverse effects on intestinal morphology. Building upon these findings, the present study aimed to expand our understanding of the transcriptomic responses in the zebrafish brain to dietary supplementation with S.
View Article and Find Full Text PDFMar Pollut Bull
September 2025
Aristotle University of Thessaloniki, School of Biology, Department of Botany, GR-541 24 Thessaloniki, Greece.
Cyanobacteria produce a diverse array of bioactive secondary metabolites, encompassing both harmful and potentially beneficial compounds. This study evaluated the effects of five cyanobacterial strains with uncharacterized metabolomes, including the new species Komarekiella chia, Nodularia mediterranea, and Iphianassa zackieohae-on Lemna trisulca plant. Both short-term (exposure of plant to cyanobacterial extracts for 24 h) and long-term (2-week co-cultivation) experiments were conducted.
View Article and Find Full Text PDFNPJ Microgravity
August 2025
Advanced Ceramics, University of Bremen, Bremen, Germany.
The long-term goal of establishing a sustained human presence on Mars requires the capacity to produce essential consumables on-site. To this end, we develop strategies for processing inorganic oxidic powders and biomass into highly particle-filled composites using direct ink writing (DIW) 3D printing. Our approach relies on a simulant of a Martian regolith unit rich in hydrated clay minerals and food-grade spirulina, used as proxies for local regolith and cyanobacterial biomass, respectively.
View Article and Find Full Text PDF