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Background: Frozen leads are an uncommon complication occurring in 4% to 12.5% of pacemaker replacements. Although the use of drills has been proposed as a solution, no detailed technique has been described to date.
Case Summary: We encountered a case of ventricular lead entrapment during generator replacement 9 years after pacemaker implantation. Conventional methods including silicone plug removal, vibration of the pin plug, and even the application of a bone cutter failed to resolve this issue. The lead was successfully released using a drill without causing any damage.
Discussion: Our method involved approaching the header from multiple angles with the drill, enabling safe release of the frozen lead. Innovative drilling techniques are required as the device design evolves.
Take-home Message: When managing a frozen lead, it is essential to employ the drill with appropriate modifications and technique.
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http://dx.doi.org/10.1016/j.jaccas.2025.104815 | DOI Listing |
J Neurosurg Anesthesiol
September 2025
Anesthesiology, University of Michigan, Ann Arbor, MI.
Background: Carotid blowout syndrome (CBS) is a life-threatening emergency involving the rupture of the carotid arteries and/or branches, often following surgery and radiotherapy for head and neck cancer. Our case series aimed to describe airway management strategies, endovascular and surgical approaches, perioperative resuscitation management, and clinical outcomes in a cohort of patients with CBS at a tertiary referral academic health center.
Methods: We retrospectively identified patients presenting with CBS between 2017 and 2021.
Ann Thorac Surg
September 2025
Department of Surgery, University of Cincinnati Medical Center, 231 Albert Sabin Way ML 0558, Cincinnati, OH 45267. Electronic address:
J Therm Biol
August 2025
Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB, Canada; Innovation and Portfolio Management, Canadian Blood Services, Edmonton, AB, Canada. Electronic address:
Extreme temperature fluctuations during routine handling and shipping of cryopreserved cell products significantly compromise product quality in ways that extend beyond the duration and peak temperature of the fluctuation. The type of cryoprotectant used and the initial ice nucleation temperature influence ice crystal growth during rewarming events, in turn impacting cell survival. Using a cryomicroscope together with temperature profiles recorded in cord-blood units, ice crystal growth was tracked through five transient-warming events (TWEs) that peaked at -30 °C, -20 °C, or -10 °C.
View Article and Find Full Text PDFCryobiology
September 2025
Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom. Electronic address:
Severe blood loss due to trauma, anaemia, or chemotherapy necessitates immediate red blood cell (RBC) transfusions. The short shelf-life of RBCs at 4 °C complicates emergency supply management. Glycerol is the state-of-the-art cryopreservative for RBCs but the time from thawing to transfusion is more than 1 hour, due to the slow, extensive washing process.
View Article and Find Full Text PDFWorld J Hepatol
August 2025
Department of General Surgery, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen 518107, Guangdong Province, China.
Background: Adrenal ectopia is a rare condition in which adrenal tissue is found in an abnormal location, often posing diagnostic challenges. Although generally considered benign, it can present as hepatic or other organ lesions, mimicking malignant tumors. In the liver, ectopic adrenal tissue can closely resemble hepatocellular carcinoma or metastatic disease, potentially leading to unnecessary aggressive treatments such as surgery or chemotherapy.
View Article and Find Full Text PDF