Advancing comparative placentation through spatial transcriptomics and organoid models.

PLoS Biol

Department of Pathology, University of California San Diego School of Medicine, La Jolla, California, United States of America.

Published: August 2025


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Article Abstract

The placenta is one of the most diverse organs among eutherian mammals, and comparative placentation studies can reveal fundamental processes that support a successful pregnancy. A new study in PLOS Biology uses swine placental organoids and in vivo spatial transcriptomics to uncover key insights into placental cell diversity and evolution.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12396701PMC
http://dx.doi.org/10.1371/journal.pbio.3003346DOI Listing

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