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http://dx.doi.org/10.1007/s12013-025-01850-y | DOI Listing |
Cell Biochem Biophys
August 2025
School of Pharmacy (Institute of Pharmaceutical Research), Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, 250117, Shandong, China.
Front Pharmacol
April 2025
The MOE Basic Research and Innovation Center for the Targeted Therapeutics of Solid Tumors, Department of Nutrition, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Introduction: Ferroptosis is a form of regulated cell death driven by the accumulation of iron-dependent lipid peroxides, and ferroptosis-mediated cancer therapy has gained considerable attention. Despite emerging evidence that ferroptosis induction effectively suppresses hepatocellular carcinoma (HCC) progression and enhances chemosensitivity, the development of resistance to ferroptosis-targeting therapies remains a critical challenge. Natural active compounds have great potential in cancer treatment.
View Article and Find Full Text PDFMed Oncol
August 2023
Department of Pathology, The Second Affiliated Hospital of Shandong First Medical University, Taian, 271000, People's Republic of China.
6-methoxydihydrosanguinarine (6-MS), a natural benzophenanthridine alkaloid extracted from Macleaya cordata (Willd.) R. Br, has shown to trigger apoptotic cell death in cancer cells.
View Article and Find Full Text PDFPhytother Res
January 2023
School of Pharmacy, Xi'an Jiaotong University, Xi'an, China.
6-Methoxydihydrosanguinarine (6-MDS) is a natural benzophenanthridine alkaloid extracted from Hylomecon japonica (Thunb.) Prantl. It is the first time to explore the effect and mechanism of 6-MDS in breast cancer.
View Article and Find Full Text PDFFront Pharmacol
March 2022
College of Veterinary Medicine, Qingdao Agricultural University, Qingdao, China.