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Guided bone regeneration (GBR) is essential in implant dentistry for managing bone deficiencies. Despite its high success rate, complications like wound dehiscence, membrane exposure, and infection can compromise outcomes. These issues are influenced by patient health, surgical technique, and the implanted biomaterials. Membrane exposure may lead to significant bone loss and jeopardise treatment success. A resorbable magnesium membrane has been recently introduced for GBR, but soft tissue healing complications have not yet been reported. This case series reviews four instances of wound dehiscence to assess its impact on clinical outcomes. Four patients underwent GBR using a magnesium membrane before implant placement. Each followed a similar protocol: defects were filled with bovine and autologous bone, then covered with the magnesium membrane. Membrane exposure occurred in all cases, varying from small to large. However, none experienced pain or signs of infection, and no additional treatment was required. Implant placement proceeded as planned, with no notable bone loss. Despite varying degrees of exposure, the magnesium membrane prevented infection, pain, or significant bone loss. It effectively maintained a barrier between tissues, suggesting its potential to reduce complications from exposure. Larger studies are needed to validate these findings.
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http://dx.doi.org/10.1002/jbm.b.35642 | DOI Listing |
ACS Appl Mater Interfaces
September 2025
School of Integrated Circuits, Shandong University, Jinan 250100, P. R. China.
Transient electronics that can degrade after fulfilling their designed functionalities offer transformative potentials in biomedical implants (eliminating secondary surgeries), ecofriendly consumer electronics (reducing e-waste), and secure systems. However, the development of reliable transient energy supplies remains a critical challenge, thus limiting their widespread implementation. Among various solutions, wireless power supplies via near-field inductive coupling stand out as particularly promising candidates.
View Article and Find Full Text PDFBrain Res
September 2025
Department of Geriatric Rehabilitation, Clinical Research Center for Geriatric Disorders of Guangxi Zhuang Autonomous Region, Guangxi, Jiangbin Hospital of Guangxi Zhuang Autonomous Region, No 85 Hedi Road, Nanning, 530021, Guangxi Zhuang Autonomous Region, China. Electronic address: 13657813091@163
Levofloxacin (LVFX)-associated seizures are thought to arise from disrupted excitatory-inhibitory balance, but the underlying synaptic mechanisms remain unclear. This study investigated how LVFX alters both glutamatergic and GABAergic transmission to promote neuronal hyperexcitability. We combined in vitro and in vivo approaches using primary cortical neurons treated with LVFX and adult rats administered LVFX.
View Article and Find Full Text PDFAdv Mater
September 2025
School of Resources and Environmental Engineering, Wuhan University of Technology, Wuhan, 430070, China.
Owing to the crucial role in energy transformation for decarbonization, sustainable lithium (Li) supply has become growingly critical. Low-quality brines hold vast potential due to infinite reserves and diverse distribution but desire green and cost-effective extraction techniques against low Li concentrations and high magnesium-to-lithium ratios. Solar-driven direct lithium extraction (SDLE) systems combining conventional evaporation and DLE techniques can overcome the present challenges of Li extraction, promising to advance the exploitation of low-quality brines while simultaneously producing fresh water.
View Article and Find Full Text PDFACS Appl Mater Interfaces
September 2025
Department of Pediatric Dentistry (Department of Preventive Dentistry), School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University, No.44-1 Wenhua Road West, 250012 Jinan, Shandong, China.
Guided bone regeneration (GBR) is a prominent focus in biomedical materials research, yet few studies address practical clinical needs. GBR membranes must fulfill the "PASS" principles to be effective in surgery, but existing membranes often fall short in balancing antibacterial activity, controlled degradation, osteoinductive potential, and mechanical support. In this study, we employed laser powder bed fusion (LPBF) to fabricate a porous WE43 magnesium alloy scaffold suitable for large alveolar bone defects.
View Article and Find Full Text PDFJ Phys Chem Lett
September 2025
Department of Chemistry, University of Manchester, Oxford Road, Manchester M13 9PL, U.K.
Two-dimensional ion-selective membranes provide an appealing avenue for extracting lithium from naturally occurring aqueous brine solutions. Most current work is focused on graphene-based membranes, where the dynamics of ion permeation is determined by noncovalent pore-ion interactions, and the main challenge is achieving precise control over the pore size. Here, we propose that porphyrins, macrocycles with atomically precise pores ∼2.
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