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Chronic dermatologic diseases are characterized by pathophysiologic complexity and the existence of many unmet patient management needs that can contribute to treatment failure, with poor adherence being a major issue. This study aims to identify key topics in this field, using the Web of Science database. To perform this analysis, tools such as VOSviewer, Bibliometrix, and Excel were used. A Python script leveraging machine learning algorithms was developed to standardize terminology. The initial search yielded 35,373 documents, which were then refined to 12,952 publications spanning 1975 to 2024 through parameter optimization. The study found an increasing interest in this research domain, with a notable surge in 2019. The analysis identified the United States, Germany, and England as the most prolific countries in terms of scientific output. Canada ranked sixth in total document production, but its documents received the highest average citations, reflecting a significant impact. Normalization analysis revealed Italy as the most specialized country in chronic skin disease research relative to total national research output. Trend analysis revealed an evolution in research topics, particularly after 2020, with a growing focus on personalized treatment methods and long-term treatment outcomes. The study highlighted international collaboration, especially among countries with cultural or regional connections, such as those within the European Union. It underscores the growing need for continuous updates and the increasing global focus on chronic skin diseases, highlighting the critical role of staying current with emerging trends to drive advancements in treatment and patient care.
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http://dx.doi.org/10.3390/bioengineering12080890 | DOI Listing |
Clin Epigenetics
September 2025
Department of Psychiatry and Psychotherapy, Philipps University Marburg, Marburg, Germany.
Background: Work-related stress is a well-established contributor to mental health decline, particularly in the context of burnout, a state of prolonged exhaustion. Epigenetic clocks, which estimate biological age based on DNA methylation (DNAm) patterns, have been proposed as potential biomarkers of chronic stress and its impact on biological aging and health. However, their role in mediating the relationship between work-related stress, physiological stress markers, and burnout remains unclear.
View Article and Find Full Text PDFBMC Public Health
September 2025
Department of Dermatology and Allergy, TUM School of Medicine and Health, Technical University of Munich, Biedersteiner Str. 29, 80802, Munich, Germany.
Background: Psoriasis, a chronic inflammatory skin disorder, imposes a high burden on those affected, often leading to stigma and increased depression risk. With the increasing importance of digital media in medical contexts, there is a notable prevalence of misinformation and low-quality content. This study aims to explore the experiences of individuals affected by psoriasis regarding their disease-related digital media use.
View Article and Find Full Text PDFAesthetic Plast Surg
September 2025
Department of Otolaryngology, Masih Daneshvari Hospital, Neyavran, Darabad, Tehran, Iran.
Nasal alar reconstruction is complex due to the region's anatomy and aesthetic importance. This report describes repairing a small, full-thickness alar rim defect in a 36-year-old man using a rotational columellar skin flap with septal cartilage grafting. This single-stage technique achieved good color match, symmetry, and minimal donor-site morbidity.
View Article and Find Full Text PDFSpinal Cord Ser Cases
September 2025
Rehabilitation Sciences Institute, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Study Design: Concurrent mixed methods case series.
Objectives: To examine the feasibility and effect of a peer-facilitated, remote handcycling sport program on physical, psychological, and social health of individuals with spinal cord injury or disease (SCI/D) aged ≥50 years.
Setting: Participants' homes.
Biomed Mater
September 2025
Department of Nanobiotechnology, Faculty of Biological Sciences, , Tarbiat Modares University, Tehran, P.O. Box 14115-154, Iran, Tehran, Tehran Province, 14115-154, Iran (the Islamic Republic of).
It is essential to develop new strategies for wound treatment and skin reconstruction, particularly by scaffolds that replicate the structure and function of native skin. A bilayer scaffold was developed using three-dimensional (3D) bioprinting, based on a uniform chitosan-based formulation for both layers, maintaining material uniformity while offering structural support and promoting cell adhesion. The upper chitosan layer, embedded with NHEK-Neo, is stiffer and mimics the epidermis, while the softer lower layer contains embedded HFFs and HFSCs, mimicking the dermis.
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