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INDKK, an oleaginous red yeast isolated from mangrove forest soil, efficiently metabolizes biomass hydrolysates and accumulates lipids of more than 60% of its dry weight. Hybrid genome assembly (Illumina and Oxford Nanopore) produced 24 scaffolds comprising a 21.05 Mb nuclear and ~26 kb mitochondrial genome.
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http://dx.doi.org/10.1128/mra.00317-25 | DOI Listing |
Neural Regen Res
September 2025
Department of Neurosurgery, the Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, China (Zhao N, Guo M).
Front Genet
August 2025
4th Department of Internal Medicine, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Transcriptional enhancers are DNA regulatory elements that control the levels and spatiotemporal patterns of gene expression during development, homeostasis, and pathophysiological processes. Enhancer identification and characterization at the genome-wide scale rely on their structural characteristics, such as chromatin accessibility, binding of transcription factors and cofactors, activating histone modifications, 3D interactions with other regulatory elements, as well as functional characteristics measured by massively parallel reporter assays and sequence conservation approaches. Recently, machine learning approaches and particularly deep learning models (Enformer, BPNet, DeepSTARR, etc.
View Article and Find Full Text PDFMaterials (Basel)
August 2025
Department of Architecture, Faculty of Environmental Engineering, The University of Kitakyushu, 1-1 Hibikino Wakamatsu, Kitakyushu, Fukuoka 8080135, Japan.
The mitigation of early-age shrinkage and thermal cracking remains a pressing challenge in mass concrete structures. This study introduces a novel temperature-control admixture (TCA), formulated with gel-forming inorganic compounds, designed to suppress internal temperature rise while improving the mechanical stability of fly ash concrete. Four concrete mixes with TCA dosages of 0, 0.
View Article and Find Full Text PDFMicrobiol Resour Announc
August 2025
Yeast Biofuel Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India.
INDKK, an oleaginous red yeast isolated from mangrove forest soil, efficiently metabolizes biomass hydrolysates and accumulates lipids of more than 60% of its dry weight. Hybrid genome assembly (Illumina and Oxford Nanopore) produced 24 scaffolds comprising a 21.05 Mb nuclear and ~26 kb mitochondrial genome.
View Article and Find Full Text PDFNPJ Biomed Innov
August 2025
Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI USA.
High-grade serous tubo-ovarian cancer (HGSC) is marked by substantial inter- and intra-tumor heterogeneity. The tumor microenvironments (TME) of HGSC show pronounced variability in cellular make-up across metastatic sites, which is linked to poorer patient outcomes. The influence of cellular composition on therapy sensitivity, including chemotherapy and targeted treatments, has not been thoroughly investigated.
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