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Anomalous systemic arterial supply to the left lower lobe (ASALLL) is a rare congenital vascular malformation. It predominantly occurs in young and middle-aged adults, often presenting with recurrent hemoptysis of unknown etiology. The condition has a high clinical misdiagnosis rate, and its optimal treatment remains controversial. Traditional management involves surgical or thoracoscopic lobectomy with ligation of the anomalous artery. In recent years, with advancements in endovascular techniques, transcatheter arterial embolization (TAE) has gained increasing preference among patients due to its minimally invasive and highly effective nature. Previous cases have primarily employed coils or vascular plugs to occlude the anomalous artery, with no reported use of detachable coil combined with medical tissue glue for embolization. Here, we present the case of an 18-year-old male with hemoptysis, diagnosed with ASALLL via CTA, who underwent successful embolization of the anomalous systemic artery using detachable coils combined with medical tissue glue. The procedure was uneventful, with excellent postoperative recovery. At the 1-year follow-up, the patient remained asymptomatic, with no complications such as pulmonary necrosis or infection. We also reviewed recent literature on the diagnosis and management of this condition, discussing key points in its diagnosis and differential diagnosis, and comparing the advantages and disadvantages of surgical intervention versus TAE. It aims to provide more robust evidence for the accurate diagnosis and optimal treatment selection of this rare vascular anomaly.
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http://dx.doi.org/10.3389/fmed.2025.1627401 | DOI Listing |
Ophthalmic Genet
September 2025
Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA.
Introduction: A congenital optic nerve head anomaly (CONHA) is an umbrella term for structurally abnormal optic nerve heads present at birth which may lead to vision loss. The potential roles of motile and non-motile ciliopathies in this process are not well understood. This report describes a pediatric case of CONHA and implicates a motile ciliopathy in a possible mechanism that affects embryogenesis of the optic nerve head.
View Article and Find Full Text PDFFront Med (Lausanne)
August 2025
Department of Intervention and Vascular, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, China.
Anomalous systemic arterial supply to the left lower lobe (ASALLL) is a rare congenital vascular malformation. It predominantly occurs in young and middle-aged adults, often presenting with recurrent hemoptysis of unknown etiology. The condition has a high clinical misdiagnosis rate, and its optimal treatment remains controversial.
View Article and Find Full Text PDFCongenital pulmonary airway malformations (CPAM) are rare congenital pulmonary anomalies in adults and are at risk of malignant transformation. CPAM lesions with abnormal systemic blood supply are considered hybrid lesions (HL). There are few cases of HL in adults.
View Article and Find Full Text PDFJ Assoc Physicians India
July 2025
Professor, Department of Cardiology, Government Medical College and Hospital, Chandigarh, India.
Total anomalous pulmonary venous connection (TAPVC) is a rare cyanotic congenital heart disease with abnormal drainage of pulmonary veins (PVs) into a systemic vein or right atrium (RA). It is divided into four types on the basis of anatomical pattern of drainage: supracardiac, cardiac, infracardiac, and mixed type. The mixed variant is further divided into the "3 + 1" and "2 + 2" patterns.
View Article and Find Full Text PDFAm J Cardiol
August 2025
Department of Pediatrics, Institute of Science Tokyo, Tokyo, Japan; Tokyo Health Care University, Tokyo, Japan. Electronic address:
Pulmonary hypertension (PH) is a serious complication that impairs the prognosis of congenital heart disease (CHD) patients. The Japanese Association of Congenital Heart Disease with Pulmonary Hypertension Registry (JACPHR) is a nationwide CHD-PH registry in Japan, established in 2021. We aimed to clarify the current status of pharmacological treatment for CHD-PH using JACPHR data.
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