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Article Abstract
Objective: This study reports a familial Gelsemium elegans poisoning case and systematically evaluates the efficacy of gastric lavage in intoxication through a meta-analysis.
Methods: We systematically searched PubMed, Web of Science, CNKI, and Wanfang Data (2000-2024). Eligible randomized controlled trials and case reports comparing gastric lavage versus non-lavage approaches were included. Data were extracted from published studies, and pooled odds ratios (ORs) with 95% confidence intervals (CIs) were calculated using Mantel-Haenszel random-effects models.
Results: Thirteen studies involving 160 patients demonstrated an overall in-hospital mortality of 18.75%. Gastric lavage suggested potential survival benefit compared to controls (OR 0.39; 95% CI 0.15-0.99; = 0.62).
Conclusion: poisoning is life-threatening, with severe cases rapidly progressing to respiratory/circulatory failure requiring urgent support. Gastric lavage may offer survival advantage in hemodynamically stable patients when performed with airway protection. Prompt respiratory support should be prioritized in the therapeutic management.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12375676 | PMC |
| http://dx.doi.org/10.3389/fpubh.2025.1633727 | DOI Listing |
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