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Article Abstract

Purpose: To evaluate the value of conventional ultrasound and contrast-enhanced ultrasound (CEUS) in predicting the risk of recurrence in patients with ipsilateral anterior circulation ischemic stroke (ACIS).

Methods: The clinical, laboratory, and ultrasound data of 295 patients who were hospitalized for their initial ACIS between January 2016 and May 2023 were collected. Based on 6–24 months follow-up results, patients were categorized into two groups: the recurrence group and the non-recurrence group. Differences in clinical characteristics, laboratory tests, and ultrasound findings between the two groups were analyzed.

Results: Statistically significant differences were observed between the recurrence and non-recurrence groups in terms of age, carotid plaque side, and CEUS grade ( < 0.05). Multivariate analysis identified CEUS grade as an independent risk factor for ACIS recurrence( = 0.032). A CEUS grade ≥ 2 demonstrated high predictive accuracy for recurrence, with a sensitivity of 91.04%, specificity of 85.09%, and overall accuracy of 86.44%.

Conclusion: CEUS grade could independently predict the recurrence risk of ipsilateral ACIS, providing valuable insights for the clinical management and prevention of recurrent ipsilateral ACIS in this patient population.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12379353PMC
http://dx.doi.org/10.1186/s12880-025-01887-8DOI Listing

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