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Purpose: To determine the recovery kinetics of performance, muscle damage, and neuromuscular fatigue following 2 speed-endurance maintenance training (SEMT) protocols in soccer.
Methods: Ten well-trained male soccer athletes randomly completed 3 trials: work-to-rest ratio SEMT/1:3, SEMT/1:1, and a control trial. Training load during SEMT was monitored using a global positioning system and heart-rate monitors. Isokinetic strength of knee extensors and flexors; repeated-sprint ability (RSA); speed 10-, 30-m, countermovement jump (CMJ); and muscle damage (delayed-onset muscle soreness [DOMS] and creatine kinase) markers were evaluated at baseline and at 0, 24, 48, and 72 hours posttraining. Maximal voluntary contraction of knee extensors and flexors was additionally assessed at 1, 2, and 3 hours posttraining.
Results: Strength (eccentric torque) and speed performance (RSA, 10-m and 30-m sprint times) were reduced (P < .05) following the SEMT/1:3 for up to 72 and 48 hours, respectively, and following SEMT/1:1 for up to 48 and ≤24 hours, respectively. Eccentric torque and RSA deterioration was greater in SEMT/1:3 compared to SEMT/1:1 at 72 hours and immediately postexercise, respectively (P < .05). Indicators of neuromuscular fatigue (CMJ and maximal voluntary contraction) declined in SEMT/1:3 at 24 and 2 hours postexercise (P < .05) and in SEMT/1:1 immediately and at 2 hours postexercise (P < .05). Muscle damage (DOMS) in the knee flexors was elevated in both SEMT protocols for up to 48 hours (P < .05).
Conclusions: SEMT/1:3 induces short-term neuromuscular fatigue; provokes a decrease of strength (48-72 h), speed and RSA (48 h), and jump height (24 h); and is related with an elevation of knee flexors' DOMS (48 h). Increased work-to-rest ratio causes higher levels of exercise-induced muscle damage.
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http://dx.doi.org/10.1123/ijspp.2025-0084 | DOI Listing |
Life Sci Alliance
November 2025
Department of Viroscience, Erasmus MC, Rotterdam, The Netherlands
Enterovirus D68 (EV-D68) is an emerging respiratory virus associated with extra-respiratory complications, especially acute flaccid myelitis. However, the pathogenesis of acute flaccid myelitis is not fully understood. It is hypothesised that through infection of skeletal muscles, the virus further infects motor neurons via the neuromuscular junction.
View Article and Find Full Text PDFCarbohydr Polym
November 2025
Tianjin Key Laboratory of Food Biotechnology, College of Biotechnology and Food Science, Tianjin University of Commerce, Tianjin 300134, China; Key Laboratory of Low Carbon Cold Chain for Agricultural Products, Ministry of Agriculture and Rural Affairs, Tianjin 300134, China. Electronic address: wzj
For purpose of overcoming the negative impact of high-dose phenols on meat quality, xanthan gum (XG), a natural anionic polysaccharide, was employed to prevent the undesirable interaction between myofibrillar protein (MP) and gallic acid (GA, 150 μmol/g) and ameliorate the gel and emulsification characteristics of MP. XG dose-dependently alleviated the structural damage of MP caused by GA and reduced protein aggregation, manifested as the decrease in surface hydrophobicity, turbidity and aggregate size (p < 0.05) and increase in α-helix content and intrinsic fluorescence.
View Article and Find Full Text PDFBiotechnol J
September 2025
College of Medicine, Al-Ayen Iraqi University, An Nasiriyah, Iraq.
Cardiac tissue engineering (CTE) is a rapidly evolving field that combines cells, scaffolds, and biofabrication methods to repair damaged heart tissue. New technologies have made it possible to utilize AI in designing cardiac patches and 4D bioprinting to create biomaterials that respond to time. These procedures are a big step forward from traditional ones since they offer more accuracy, flexibility, and the possibility of therapies that are tailored to each patient.
View Article and Find Full Text PDFAndrology
September 2025
Department of Urology, Knuppe Molecular Urology Laboratory, School of Medicine, University of California, San Francisco, California, USA.
Background: Current treatments for diabetic erectile dysfunction, such as phosphodiesterase type 5 inhibitors, penile injection, or vacuum erection devices, primarily offer symptomatic relief and do not address the underlying pathophysiology, which involves neural, vascular, and smooth muscle degeneration.
Objectives: This study aimed to evaluate the therapeutic potential of amniotic fluid-derived stem cells in a rat model of diabetic erectile dysfunction by assessing their impact on erectile function and penile tissue regeneration.
Methods: Male Sprague‒Dawley rats were divided into control, diabetic, and amniotic fluid-derived stem cell-treated diabetic groups.
Crit Rev Clin Lab Sci
September 2025
Celiac Disease and Gluten Related Disorders Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Celiac disease (CD) is a chronic autoimmune disorder triggered by gluten ingestion, causing intestinal damage and systemic complications. Essential amino acids (EAAs) play crucial roles in immune function, intestinal integrity, and metabolic regulation; however, their malabsorption in CD contributes to disease progression. Tryptophan dysregulation may influence mood disorders in CD, while phenylalanine and lysine are linked to immune activation and gluten modification.
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