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http://dx.doi.org/10.1177/19433654251366894 | DOI Listing |
Med Eng Phys
October 2025
Ansys Inc., Houston, TX 77094, USA.
Introduction: Benchtop and animal models have traditionally been used to study the propagation of Onyx Liquid Embolic Systems (Onyx) used in the treatment of brain arteriovenous malformations (AVM). However, such models are costly, do not provide sufficient detail to elucidate how variations in Onyx viscosity alter flow dynamics, and rely on some trial-and-error, resulting in elongated timelines for product development.
Objectives: The goal of this study was to leverage Computational Fluid Dynamics (CFD) simulations to predict the behavior of different Onyx formulations.
IEEE Trans Biomed Circuits Syst
September 2025
Neuroprostheses capable of providing Somatotopic Sensory Feedback (SSF) enables the restoration of tactile sensations in amputees, thereby enhancing prosthesis embodiment, object manipulation, balance and walking stability. Transcutaneous Electrical Nerve Stimulation (TENS) represents a primary noninvasive technique for eliciting somatotopic sensations. Devices commonly used to evaluate the effectiveness of TENS stimulation are often bulky and main powered.
View Article and Find Full Text PDFInterv Neuroradiol
September 2025
Department of Neurosurgery, Shinshu University School of Medicine, Matsumoto, Japan.
BackgroundA stable guiding system is essential for successful carotid artery stenting (CAS), particularly when navigating tortuous aortic or supra-aortic anatomy. However, data on the mechanical behavior of stent delivery systems remain scarce.ObjectiveTo assess and compare the bending stiffness and trackability of five commercially available carotid stent delivery systems using bench-top experiments.
View Article and Find Full Text PDFChem Rec
September 2025
School of Physics and Mechanics, Wuhan University of Technology, Wuhan, 430070, Hubei, P. R. China.
The development of sensors for monitoring breath acetone, a key biomarker for ketosis in diabetes mellitus, represents a critical frontier in medical diagnostics, promising a painless alternative to invasive blood tests. This review provides a comprehensive and critical evaluation of the state-of-the-art in acetone gas sensing technologies, including chemiresistive, optical, electrochemical, conductometric, and microwave platforms. We focus specifically on recent breakthroughs driven by advanced materials, analyzing how novel nanostructures from two-dimensional (2D) materials such as MXenes to porous metal-organic frameworks (MOFs) are engineered to push performance to clinically relevant parts-per-billion (ppb) sensitivity.
View Article and Find Full Text PDFCan Prosthet Orthot J
February 2025
Department of Biomedical Engineering, Faculty of Engineering, University of Strathclyde, Glasgow, Scotland.
Background: Poor post-amputation healing delays prosthetic fitting, adversely affecting mortality, quality of life, and cardiovascular health. Current residual limb assessments are subjective and lack standardized guidelines, emphasizing the need for objective biomarkers to improve healing and prosthesis readiness assessments.
Objectives: This review aimed to identify predictive, diagnostic, and indicative chemical biomarkers of healing of the tissues and structures found in the residual limbs of adults with amputation.