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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12370095 | PMC |
| http://dx.doi.org/10.4103/heartviews.heartviews_3_25 | DOI Listing |
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Purpose: The purpose of this document is to review current methods for cervical ripening and to summarize the effectiveness of these approaches based on appropriately conducted outcomes-based research. This document focuses on cervical ripening in individuals with term, singleton, vertex pregnancies with membranes intact, because this is the population in whom most studies were conducted. For more information on recommended timing of delivery based on maternal, fetal, and obstetric conditions and on labor management, refer to: American College of Obstetricians and Gynecologists (ACOG) Committee Opinion No.
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State Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, 611130, China.
Ferroptosis is a form of iron-regulated cell death that plays a critical role in various aspects of female reproductive system development. These processes include the normal estrous cycle, ovarian formation, follicular maturation, ovulation, and pregnancy, all of which are essential for maintaining reproductive health in female animals. However, excessive iron leads to the accumulation of reactive oxygen species within cells, disrupting intracellular redox balance, inducing mitophagy, membrane rupture, and lipid peroxidation, which can damage tissues and cells, ultimately resulting in ferroptosis.
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A Comparison of Synthetic Osmotic Dilators and Pharmacologic Agents for Cervical Ripening in Induction of Labor: A Systematic Review and Meta-Analysis.
J Midwifery Womens Health
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College of Nursing, Research Institute of Nursing Innovation, Kyungpook National University, Daegu, South Korea.
Introduction: Given the rising number of studies on synthetic osmotic dilators, there is a lack of comprehensive reviews for their use compared with other commonly used cervical ripening methods. This study aimed to examine the maternal and neonatal safety and efficacy in cervical ripening and labor induction using synthetic osmotic dilators compared with pharmacologic agents (prostaglandin E, prostaglandin E, oxytocin) for labor induction.
Methods: A systematic review and meta-analysis of randomized controlled trials (RCTs) and cohort studies was conducted, using MEDLINE, Embase, CINAHL, and Cochrane Library databases search.
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The First Clinical School of Nanjing University of Chinese Medicine, Nanjing, China.
Ferroptosis is a regulated, non-apoptotic form of cell death marked by the accumulation of iron-dependent lipid peroxides. This process causes rapid rupture of the plasma membrane and the release of intracellular contents. Ferroptosis acts as an intrinsic tumor-suppressive mechanism.
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