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The primary objective of modern healthcare systems is to enhance public health by providing efficient, reliable, and well-structured solutions. Improving patient satisfaction through tailored medical services has driven rapid advancements in healthcare, leading to increased competition and system complexity. However, the expansion of healthcare services introduces challenges such as high data volume, latency, response time constraints, and security vulnerabilities. To address these issues, fog computing offers an effective solution by processing data closer to end devices, reducing latency, and enabling real-time responses. This research proposes a robust brain tumor detection framework within a fog-based smart healthcare infrastructure. The process begins with data placement leveraging an improved evolutionary technique for Image Processing (HETS-IP) to optimize fog node placement based on key parameters such as energy efficiency and latency. Specifically, the Particle Swarm Optimization (PSO) algorithm is enhanced with a direct binary encoding technique, in which solutions are represented as binary strings, making it suitable for problems where decisions are discrete. This approach allows efficient optimization in binary decision spaces and improves adaptability for complex placement problems. Once data placement is committed, the tumor detection framework is performed directly at fog nodes to enhance real-time processing. This phase will begin with preprocessing, where a bilateral filter is applied to reduce noise while preserving critical edge details. Next, feature extraction is utilized to derive statistical texture features, which capture diagnostic information essential for distinguishing between tumor types. The process continues by classification using a deep Convolutional Neural Network (CNN) with sequential architecture to classify tumors. Simulation results demonstrate that HETS-IP outperforms traditional evolutionary algorithms, including Ant Colony Optimization (ACO), Genetic Algorithm-Simulated Annealing (GASA), and Genetic Algorithm (GA). On average, HETS-IP reduces energy consumption by 5%, 9%, and 14% and decreases makespan by 4%, 6%, and 11%, respectively. Additionally, the proposed approach achieves an accuracy of 97% and a precision of 96%, ensuring highly reliable brain tumor detection.
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http://dx.doi.org/10.1038/s41598-025-16042-0 | DOI Listing |
Pathol Res Pract
September 2025
Department of Pathology, Xijing Hospital and School of Basic Medicine, Fourth Military Medical University, Xi'an, China. Electronic address:
Background: Dermal clear cell sarcoma (DCCS) is a rare malignant mesenchymal neoplasm. Owing to the overlaps in its morphological and immunophenotypic profiles with a broad spectrum of tumors exhibiting melanocytic differentiation, it is frequently misdiagnosed as other tumor entities in clinical practice. By systematically analyzing the clinicopathological characteristics, immunophenotypic features, and molecular biological properties of DCCS, this study intends to further enhance pathologists' understanding of this disease and provide a valuable reference for its accurate diagnosis.
View Article and Find Full Text PDFJCO Precis Oncol
September 2025
Cell Biology and Biotherapy Unit, Istituto Nazionale Tumori IRCCS Fondazione G. Pascale, Napoli, Italy.
Purpose: Tumor comprehensive genomic profiling (CGP) may detect potential germline pathogenic/likely pathogenic (P/LP) alterations as secondary findings. We analyzed the frequency of potentially germline variants and large rearrangements (LRs) in the RATIONAL study, an Italian multicenter, observational clinical trial that collects next-generation sequencing-based tumor profiling data, and evaluated how these findings were managed by the enrolling centers.
Patients And Methods: Patients prospectively enrolled in the pathway-B of the RATIONAL study and undergoing CGP with the FoundationOne CDx assays were included in the analysis.
JMIR Cancer
September 2025
Cancer Patients Europe, Rue de l'Industrie 24, Brussels, 1000, Belgium.
Background: Breast cancer is the most common cancer among women and a leading cause of mortality in Europe. Early detection through screening reduces mortality, yet participation in mammography-based programs remains suboptimal due to discomfort, radiation exposure, and accessibility issues. Thermography, particularly when driven by artificial intelligence (AI), is being explored as a noninvasive, radiation-free alternative.
View Article and Find Full Text PDFArq Bras Cir Dig
September 2025
Universidade de São Paulo, Faculty of Medicine, Department of Gastroenterology, Colonoscopy Division - São Paulo (SP), Brazil.
Background: Artificial intelligence (AI)-assisted colonoscopy has emerged as a tool to enhance adenoma detection rates (ADRs) and improve lesion characterization. However, its performance in real-world settings, especially in developing countries, remains uncertain.
Aims: The aim of this study was to evaluate the impact of AI on ADRs and its concordance with histopathological diagnosis.
Ann Acad Med Singap
August 2025
Division of Medical Oncology, National Cancer Centre Singapore, Singapore.
Introduction: The high prevalence and mortality rates of breast cancer and lung cancer in Singapore necessitate robust screening programmes to enable early detection and intervention for improved patient outcomes, yet 2024 uptake and coverage remain suboptimal. This narrative review synthesises expert perspectives from a recent roundtable discussion and proposes strategies to advance breast cancer and lung cancer screening programmes.
Method: A 2024 roundtable convened clinical practitioners, health policymakers, researchers and patient advocates discussed current challenges and opportunities for improving cancer screening in Singapore.