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Objective: In the 2022 match cycle preference signaling was introduced to general surgery. For 3 years (2022-2024) each applicant was able to use 5 signals to indicate a preference for a program. In 2024, the average number of ranked programs among applicants was 12 demonstrating that programs were creating their interview list beyond those who signaled. For the 2025 match cycle, the number of signals rose to 15 which allowed our program to review and offer interviews to only those applicants who signaled a preference. We compare the key demographics of applicants for the 2023, 2024 and 2025 match cycle to see if there was a difference with this approach.
Design, Setting, And Participants: At our academic medical center, to create our interview list, each year we holistically review approximately 300 applications using a scoring rubric, with each application reviewed by the PD or APD, and a second faculty member. In 2023, 761 applications were screened by a diverse group of faculty in a labor-intensive process to reach the 300 applications. In 2024, the group of 300 was created partially from those who signaled (148) with the balance selected again by a diverse group of faculty. In 2025 the entire list was created from applicants who signaled us, eliminating entirely this first step in our screening. To evaluate differences in the approaches, we looked at the following variables in each of the groups selected for holistic review: gender, race, geographic region of medical school, reviewer score and step 2 score. We performed chi squared analysis for the categorical variables and t-test for continuous variables using R. ANOVA analysis was used when comparing continuous variables for all 3 groups RESULTS: There was no significant difference in the demographics of applicants that underwent holistic review between the 3 years. In 2024, there was no difference in demographics of holistically reviewed applicants between faculty chosen applicants and applicants who preference signaled.
Conclusions: Using signals only as a method to screen applicants saved a step in the review process without affecting the demographics of applicants. Preference signaling can be a valuable tool to streamline the interview selection process with little impact on the quality and demographics of the group.
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http://dx.doi.org/10.1016/j.jsurg.2025.103656 | DOI Listing |
Neurol Res
September 2025
Department of Neurology, The First Affiliated Hospital of Jiamusi University, Jiamusi, People's Republic of China.
Background: We conducted a transcriptomic analysis to examine cerebellar transcriptional changes in a mouse model of chronic intermittent alcohol exposure.
Methods: We established a mouse model of chronic intermittent alcohol exposure and conducted a cerebellar transcriptomic analysis. After identifying differentially expressed genes, we analyzed pathway enrichment using the Kyoto Encyclopedia of Genes and Genomes and Gene Ontology.
Nucleic Acids Res
September 2025
Department of Applied Science and Technology, Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129 Torino, Italy.
Cells may exploit oscillatory gene expression to encode biological information. Temporal features of oscillations, such as pulse frequency and amplitude, are determinant for the outcome of signalling pathways. However, little effort has been devoted to unveiling the role of pulsatility in the context of post-transcriptional gene regulation, where microRNAs act by binding to RNAs and regulate their expression.
View Article and Find Full Text PDFAndrology
September 2025
Department of Urology, The Second Affiliated Hospital of Shanxi Medical University, Taiyuan, China.
Background: Drug-induced hypogonadism is an underrecognized but significant adverse effect of various medications, contributing to male sexual dysfunction and infertility. Despite its clinical significance, comprehensive studies systematically identifying high-risk drugs remain limited.
Objectives: This study aimed to investigate the potential drugs associated with hypogonadism from FDA Adverse Event Reporting System.
Food Funct
September 2025
Department of Chemical and Pharmaceutical Engineering, College of Chemical Engineering, Huaqiao University, Xiamen, Fujian Province 361021, PR China.
Depression is a widespread mental health condition associated with impaired neuroplasticity and disrupted brain-derived neurotrophic factor (BDNF)/TrkB signaling. Black mulberry, rich in anthocyanins, shows promise as a natural intervention for its anti-oxidative and anti-inflammatory profiles. This study evaluated the antidepressant-like effects of black mulberry anthocyanins in mice subjected to chronic mild stress (CMS).
View Article and Find Full Text PDFCogn Neurodyn
December 2025
School of Mathematics, Northwest University, Xi'an, China.
This study sought to enhance visual acuity assessment using steady-state visual evoked potentials (SSVEPs) through subject-specific training methods. SSVEPs were elicited from eleven subjects using the vertical sinusoidal gratings at six various spatial frequency steps, and then the classical approach of Oz single-channel, the spatial filtering method of canonical correlation analysis (CCA), and five subject-specific training methods, i.e.
View Article and Find Full Text PDF