Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Monitoring the hydrazine (NH) level is essential for environmental and health safety, while traditional detection methods face challenges including low sensitivity, complex sample handling, and sophisticated operation. In this study, a novel fluorescent probe, ZNP, was designed and synthesized for tracking hydrazine in soils and river water. It was used for in situ monitoring of hydrazine generation in living cells. The optical performance guaranteed the high selectivity and reliable anti-interference. The most significant merit was a practical dynamic range for intuitive visualization. Additionally, the develop probe predominantly accumulated in lysosomes. Notably, ZNP integrated the fluorescent and visual signals, which enabled the naked-eye observation. This work acted as a significant step towards the practical tools for environmental toxicology applications.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s10895-025-04496-4 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Phasor and neural network approaches for rapid fluorophore fraction analysis in temporal-spectral multiplexed data.
J Biomed Opt
September 2025
Fraunhofer Institute for Microelectronic Circuits and Systems IMS, Duisburg, Germany.
Significance: The spatial and temporal distribution of fluorophore fractions in biological and environmental systems contains valuable information about the interactions and dynamics of these systems. To access this information, fluorophore fractions are commonly determined by means of their fluorescence emission spectrum (ES) or lifetime (LT). Combining both dimensions in temporal-spectral multiplexed data enables more accurate fraction determination while requiring advanced and fast analysis methods to handle the increased data complexity and size.
View Article and Find Full Text PDFPlasma membrane labelling efficiency, internalization and partitioning of functionalized fluorescent lipids as a function of lipid structure.
RSC Chem Biol
September 2025
Science for Life Laboratory, Department of Women's and Children's Health, Karolinska Institutet 17165 Solna Sweden
Labeling the plasma membrane for advanced imaging remains a significant challenge. For time-lapse live cell imaging, probe internalization and photobleaching are major limitations affecting most membrane-specific dyes. In fixed or permeabilized cells, many membrane probes either lose signal after fixation or fail to remain localized to the plasma membrane.
View Article and Find Full Text PDFAdvancements and perspectives on organelle-targeted fluorescent probes for super-resolution SIM imaging.
Chem Sci
September 2025
Institute of Optical Materials and Chemical Biology, Guangxi Key Laboratory of Electrochemical Energy Materials, School of Chemistry and Chemical Engineering, Guangxi University Nanning Guangxi 530004 China
As a cutting-edge super-resolution imaging technique, structured illumination microscopy (SIM) has been widely used in cell biology research, especially in the analysis of subcellular organelles and monitoring of their dynamic processes. Through multiple illumination and reconstruction processes, SIM breaks through the resolution limitations of traditional microscopes and can observe the fine structures within cells in real time with nanoscale resolution. This provides strong technical support for in-depth analyses of molecular mechanisms, organelle functions, signaling networks, and metabolic regulatory pathways within cells.
View Article and Find Full Text PDFOn-Target Photoassembly of Pyronin Dyes for Super-Resolution Microscopy.
Angew Chem Int Ed Engl
September 2025
Department of Optical Nanoscopy, Max Planck Institute for Medical Research, Jahnstrasse 29, 69120, Heidelberg, Germany.
Controlled photoactivation is an auspicious and emerging approach in super-resolution microscopy, offering virtually zero background signal from the marker prior to activation. Pyronins are well-established fluorophores, but due to their inherent intercalating tendency towards nucleic acids, their use has been mostly avoided in super-resolution microscopy. Here, we describe a new class of diaryl ether and diaryl silane molecules that upon photoactivation close into fluorescent (silicon-)pyronins and term them Pyronin Upon Light Irradiation (PULI).
View Article and Find Full Text PDFStrong Microbasicity in PVA/ChCl Eutectogels Induced by a Large Population of Bound Water.
J Phys Chem B
September 2025
School of Physics and Optoelectronic Engineering, Yangtze University, Jingzhou 434023, China.
Eutectogels have emerged as versatile materials for wearable electronics, optical sensors, and biomedical applications. This study introduced the first investigation of microenvironmental basicity in poly(vinyl alcohol)/choline chloride (PVA/ChCl) eutectogels using lumichrome as a fluorescent probe. The incorporation of ChCl was demonstrated to enhance the microbasicity of PVA films, as evidenced by the significant promotion of lumichrome deprotonation.
View Article and Find Full Text PDF